Asunto(s)
Enfermedad de Chagas/congénito , Adulto , Peso al Nacer , Brasil , Enfermedad de Chagas/mortalidad , Estudios Transversales , Femenino , Humanos , Recién Nacido , EmbarazoRESUMEN
We studied the association between human incidence of Trypanosoma cruzi infection and household infestation density of Panstrongylus megistus in Castro Alves, Bahia, Brazil. During a 9-year period, 19 persons seroconverted; 17 were children, 17 lived in nonplastered houses, and 13 lived in houses infested with triatomines. Although 6 seroconverting persons lived in houses where triatomines could not be found, the risk of seroconversion was significantly greater in infested houses and 16 times greater in densely infested houses (greater than 15 bugs/person-hour of search). The highest rate of seroconversion (6/100 person-years exposure) occurred in houses containing the greatest number of bugs infected with T. cruzi (greater than 6 infected bugs/person-hour). These observations suggest that vector control measures could have a dramatic impact on transmission of T. cruzi by P. megistus.
Asunto(s)
Enfermedad de Chagas/epidemiología , Insectos Vectores/parasitología , Panstrongylus/parasitología , Triatominae/parasitología , Anticuerpos/inmunología , Brasil , Enfermedad de Chagas/transmisión , Pruebas de Fijación del Complemento , Ensayo de Inmunoadsorción Enzimática , Técnica del Anticuerpo Fluorescente , Vivienda , Humanos , Rhodnius/parasitología , Triatoma/parasitología , Trypanosoma cruzi/inmunologíaAsunto(s)
Enfermedad de Chagas/epidemiología , Vigilancia de la Población , Adolescente , Adulto , Anciano , Animales , Anticuerpos/análisis , Brasil , Enfermedad de Chagas/diagnóstico , Enfermedad de Chagas/prevención & control , Niño , Preescolar , Pruebas de Fijación del Complemento , Estudios Transversales , Estudios de Evaluación como Asunto , Humanos , Técnicas para Inmunoenzimas , Lactante , Recién Nacido , Estudios Longitudinales , Persona de Mediana Edad , Trypanosoma cruzi/inmunologíaRESUMEN
The relationship of symptoms and radiographic abnormalities suggestive of esophageal motility disorders with electrocardiographic (ECG) alterations and seroreactivity to Trypanosoma cruzi was studied in a defined population in a rural area endemic for Chagas' disease in Bahia, Brazil. Between January and June 1981, 680 individuals 5 years of age or older were examined with serologic tests, ECGs and questionnaires for esophageal motility disorder. Of these, 39.9% were seropositive for Chagas' disease. Symptoms of dysphagia occurred 2.5 times more frequently among seropositive individuals than among seronegative individuals. Radiographic esophageal abnormalities were 3.6 times more frequent among seropositive individuals than among seronegative individuals in the symptomatic group. Symptoms and radiographic abnormalities were more common in men than in women although this was not statistically significant. Among seropositive individuals the percentage with symptoms of dysphagia increased with age, with a peak prevalence rate of 23.9% in the 45- to 64-year-old age group. Also, in the seropositive group, 41.7% with X-ray abnormalities of the esophagus and 26.3% with symptoms of dysphagia presented an abnormal ECG.