RESUMEN
We previously demonstrated that Lactobacillus casei K17, isolated from Korean kimchi, has high antioxidant levels in vitro and in vivo. However, its effect on Micropterus salmoides is unknown. In this study, we investigated the impact of L. casei K17 supplementation on the lipid metabolism, antioxidant response, liver histology, and fillet quality of M. salmoides. We randomly assigned 450 M. salmoides (33.0 ± 0.5 g) to six diet groups for 69 days. The diets were as follows: 0.85% normal saline; 10% skim milk powder; 1 × 108 CFU/g live L. casei K17 (LB); 1 × 108 live L. casei K17 protected by skim milk powder (MB); 1 × 108 dead L. casei K17 (DB); and L. casei K17 fermentation supernatant. MB significantly improved the crude protein, total collagen, alkaline-insoluble collagen, fiber numbers, hardness, chewiness, and gumminess of M. salmoides fillets (p < 0.05). LB significantly improved crude protein and fiber numbers (p < 0.05). Furthermore, dietary supplementation with LB, MB, and DB maintained normal liver histology, preserved liver function, and increased hepatic and hemal antioxidant status by enhancing antioxidant enzyme activities. Meanwhile, the three diets also promoted lipid metabolism by increasing HDL-C effectiveness and reducing total cholesterol, triglyceride, and low-density lipoprotein cholesterol levels in serum and liver tissues, indicating that dietary supplementation with DB, LB, and MB had hypolipidemic effects on M. salmoides. MB and LB significantly improved fillet quality and LB, MB, and DB improved hemal and hepatic lipid metabolism and antioxidant response and reduced reactive oxygen species production, protecting M. salmoides hepatic cells from injury.
RESUMEN
In this paper, we experimentally demonstrate an ultra-broadband high-performance polarization beam splitter (PBS) based on silicon-on-insulator (SOI) platform. The proposed device is based on a directional coupler consisting of a 70-nm taper-etched waveguide and a slot waveguide with a compact coupling length of 11 microns, the structure of which is suitable for a commercial two-step fabrication process. Benefiting from the preferences of coupling TM mode to slot waveguide and restricting TE mode in taper-etched waveguide, the polarization extinction ratios (PER) for TE and TM polarizations can reach as high as 30 dB and 40 dB at 1550 nm based on experimental results, respectively; besides, an ultra-wide operation bandwidth with PER >20 dB is achieved as ~175 nm from 1450 nm to 1625 nm (covering S, C and L bands), or the bandwidth with PER >25 dB is over ~120 nm from 1462 nm to 1582 nm, which is the largest operation bandwidth to the best of our knowledge. At last, the insertion losses (IL) are -0.17 dB and -0.22 dB for TE and TM polarizations at 1550 nm, respectively.