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1.
Adv Differ Equ ; 2021(1): 228, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33968144

RESUMEN

For a stochastic COVID-19 model with jump-diffusion, we prove the existence and uniqueness of the global positive solution. We also investigate some conditions for the extinction and persistence of the disease. We calculate the threshold of the stochastic epidemic system which determines the extinction or permanence of the disease at different intensities of the stochastic noises. This threshold is denoted by ξ which depends on white and jump noises. The effects of these noises on the dynamics of the model are studied. The numerical experiments show that the random perturbation introduced in the stochastic model suppresses disease outbreak as compared to its deterministic counterpart. In other words, the impact of the noises on the extinction and persistence is high. When the noise is large or small, our numerical findings show that COVID-19 vanishes from the population if ξ < 1 ; whereas the epidemic cannot go out of control if ξ > 1 . From this, we observe that white noise and jump noise have a significant effect on the spread of COVID-19 infection, i.e., we can conclude that the stochastic model is more realistic than the deterministic one. Finally, to illustrate this phenomenon, we put some numerical simulations.

2.
Adv Med ; 2020: 5317352, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32566691

RESUMEN

BACKGROUND: Though there is an effective intervention, pain after surgical intervention is undermanaged worldwide. A systematic implementation is required to increase the utilization of available evidence-based intervention to manage the inevitable pain after surgery. The aim of this research project is to develop a scalable model for managing pain after cesarean section by implementing the World Health Organization's (WHO) pain management guidelines through a combination of implementation research and quality improvement methods. METHODS: We implemented the World Health Organization (WHO) pain management guidelines using effective implementation strategies. First, we conducted a formative qualitative exploration to identify enablers and obstacles. In addition, we took base-line assessment on pain management implementation process and outcome using a checklist prepared from the guideline and an adapted American Pain Outcome assessment tool version 2010, respectively. Then, we integrated the guidelines into the existing practice by using collaborative iterative learning strategy. We analyzed the data by Statistical Packages for Social Sciences (SPSS) version 21. We compared the before and after data using chi-squared and Fischer's exact test. A change in any measurement was considered as significant at p value 0.05. RESULT: We collected data from 106 mothers before and 110 mothers after intervention implementation. We successfully integrated pain as a fifth vital sign in more than 87% (p value <0.001) of patient, and fidelity was approximately 59% (p value <0.001). In addition, we significantly improved pain outcome measures after the implementation of the intervention. Conclusion and Recommendations. A systematic approach to implement pain management guidelines was successful. We recommend the ward sustain these gains and that hospital, the region, and the nation to replicate the success.

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