1.
Org Lett
; 23(11): 4168-4172, 2021 06 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-34014099
RESUMEN
An umpolung reaction with α-hydrazonoesters was investigated, and it was found that α-N,N-dialkylaminoamides could be directly synthesized in yields up to 92% via a concomitant rearrangement of dialkylamino groups. As an application, a short synthesis of an inhibitor of glycine type-1-transporter was accomplished via subsequent functional group transformations in 28% overall yield.