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1.
J Environ Radioact ; 222: 106352, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-32892906

RESUMEN

This paper presents the levels and distribution of 210Po in different compartments of a coastal lagoon on the east coast of Uruguay (South America). Activity concentrations of 210Po have been obtained in different matrices, such as water, superficial sediments, clams (Diplodon sp.), freshwaters snails (Pomacea sp.), zooplankton, and fishes (Jenynsia sp.), collected at different points of the lagoon and during several sampling campaigns. In addition, the organic matter content of the sediment was determined to study the variation of 210Po along the lagoon. The activity concentrations of 210Po in the water samples are in the range between 1.1 ± 0.2-3.5 ± 0.4 mBq/L while in the sediment samples vary between 17.1 ± 1.4 and 540 ± 12 Bq/kg, DW. In the case of biota, the ranges obtained were 182 ± 5-265 ± 6 Bq/kg, DW in clams and 134 ± 4-1245 ± 16 Bq/kg, DW in snail samples. A good correlation of 210Po with the organic fractions of the sediment was observed (r = 0.8798, p-value < 0.001), being obtained high values for the distribution coefficient Kd (104 -105). In the biota samples, a clear difference was observed in the 210Po concentration values in both species, mainly due to the different feeding habits of both aquatic organisms, as it is reflected in the associated concentration ratios (CR). In this paper, a good set of results of 210Po, Kd, and CR have been obtained in different matrices, enhancing the limited archives available for modelers concerning these parameters for 210Po and freshwater systems.


Asunto(s)
Polonio , Monitoreo de Radiación , Animales , Monitoreo del Ambiente , Sedimentos Geológicos , Polonio/análisis , Uruguay
3.
Appl Radiat Isot ; 117: 91-95, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26867693

RESUMEN

Salamanca is the centre of a large industrial complex associated with the production and refining of oil-derived products in the state of Guanajuato, Mexico. The city also hosts a large chemical industry, and in past years a major fertilizer industry. All of them followed NORM (naturally occurring radioactive materials) industrial activities, where either raw materials or residues enriched in natural radionuclides are handled or generated, which can have an environmental radiological impact on their environmental compartments (e.g. soils and aquatic systems). In this study, activity concentrations of radionuclides from the 238U and 232Th natural series present in superficial urban soils surrounding an industrial complex in Salamanca, México, have been determined to analyse the possible environmental radiological impact of some of the industrial activities. The alpha-particle and gamma-ray spectrometry is used for the radiometric characterization. The results revealed the presence of 10-42, 11-51 and 178-811Bq/kg of 238U, 232Th and 40K, respectively, without any clear anthropogenic increment in relation to the values normally found in unaffected soils. Thus, the radioactive impact of the industrial activities on the surrounding soils can be evaluated as very low, representing no radiological risk for the health of the population.


Asunto(s)
Radiación de Fondo , Ambiente , Residuos Industriales/análisis , Monitoreo de Radiación/métodos , Residuos Radiactivos/análisis , Radioisótopos/análisis , Contaminantes Radiactivos del Suelo/análisis , México , Radioisótopos/química , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Contaminantes Radiactivos del Suelo/química
4.
J Environ Radioact ; 137: 79-87, 2014 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-25014882

RESUMEN

After the recent closure of certain phosphoric acid plants located in the South-West of Spain, it has been decided to restore a big extension (more than six hundred hectares) of salt-marshes, where some million tonnes of phosphogypsum (PG), the main by-product generated by these plants, had been disposed of. This PG is characterized by its content of high activity concentrations of several radionuclides from the uranium series, mainly (226)Ra, (210)Pb, and (210)Po and, to a lesser extent, U-isotopes. The PG disposal area can be considered as a potential source of radionuclides into their nearby environment, through the waters which percolate from them and through the efflorescences formed in their surroundings. For this reason, a detailed radioactive characterization of the mentioned waters and efflorescences has been considered essential for a proper planning of the restoration tasks to be applied in the near future in the zone. To this end, U-isotopes, (234)Th, (230)Th, (226)Ra, (210)Pb and (210)Po activity concentrations have been determined by applying both alpha-particle and gamma-ray spectrometric techniques to selected water and efflorescence aliquots collected in the area. The analysis of the obtained results has enabled to obtain information about the geochemical behaviour in the area of the different radionuclides analyzed; and the conclusion to be drawn that, in the restoration plan under preparation, both the prohibition of outflowing waters from the disposal area to the neighbouring salt-marshes, and the removal of all the efflorescences now disseminated in their surroundings are essential.


Asunto(s)
Sulfato de Calcio/análisis , Fósforo/análisis , Radioisótopos/análisis , Instalaciones de Eliminación de Residuos , Contaminantes Radiactivos del Agua/análisis , Humedales , Minería , Salud Pública , Monitoreo de Radiación , España , Espectrometría gamma
5.
Appl Radiat Isot ; 92: 58-72, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25005051

RESUMEN

The Constant Flux: Constant Sedimentation (CF:CS) and Constant Rate of Supply (CRS) of unsupported⧸excess (210)Pb models have been applied to a (210)Pb data set providing of eighteen sediments profiles sampled at four riverine systems occurring in Brazil, South America: Corumbataí River basin (S1=Site 1, São Paulo State), Atibaia River basin (S2=Site 2, São Paulo State), Ribeirão dos Bagres basin (S3=Site 3, São Paulo State) and Amazon River mouth (S4=Site 4, Amapá State). These sites were chosen for a comparative evaluation of the performance of the CF:CS and CRS models due to their pronounced differences on the geographical location, geological context, soil composition, biodiversity, climate, rainfall, and water flow regime, among other variable aspects. However, all sediments cores exhibited a common denominator consisting on a database built from the use of the same techniques for acquiring the sediments major chemical composition (SiO2, Al2O3, Na2O, K2O, CaO, MgO, Fe2O3, MnO, P2O5, TiO2 and LOI-Loss on Ignition) and unsupported/excess (210)Pb activity data. In terms of sedimentation rates, the performance of the CRS model was better than that of the CF:CS model as it yielded values more compatible with those expected from field evidences. Under the chronological point of view, the CRS model always provided ages within the permitted range of the (210)Pb-method in the studied sites, whereas the CF:CS model predicted some values above 150 years. The SiO2 content decreased in accordance with the LOI increase in all cores analyzed and such inverse relationship was also tracked in the SiO2-LOI curves of historical trends. The SiO2-LOI concentration fluctuations in sites S1 and S3 also coincided with some Cu and Cr inputs in the drainage systems.

6.
Braz J Med Biol Res ; 43(2): 139-49, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19893994

RESUMEN

Toxoplasma, which infects all eukaryotic cells, is considered to be a good system for the study of drug action and of the behavior of infected host cells. In the present study, we asked if thiosemicarbazone derivatives can be effective against tachyzoites and which morphological and ultrastructural features of host cells and parasites are associated with the destruction of Toxoplasma. The compounds were tested in infected Vero cell culture using concentration screens (0.1 to 20 mM). The final concentration of 1 mM was chosen for biological assay. The following results were obtained: 1) These new derivatives decreased T. gondii infection with an in vitro parasite IC50% of 0.2-0.7 mM, without a significant effect on host cells and the more efficient compounds were 2, 3 (thiosemicarbazone derivatives) and 4 (thiazolidinone derivative); 2) The main feature observed during parasite elimination was continuous morphological disorganization of the tachyzoite secretory system, progressive organelle vesiculation, and then complete disruption; 3) Ultrastructural assays also revealed that progressive vesiculation in the cytoplasm of treated parasites did not occur in the host cell; 4) Vesiculation inside the parasite resulted in death, but this feature occurred asynchronously in different intracellular tachyzoites; 5) The death and elimination of T. gondii was associated with features such as apoptosis-like stage, acidification and digestion of parasites into parasitophorous vacuoles. Our results suggest that these new chemical compounds are promising for the elimination of intracellular parasites by mainly affecting tachyzoite development at 1 mM concentration for 24 h of treatment.


Asunto(s)
Antiprotozoarios/farmacología , Tiazoles/farmacología , Tiosemicarbazonas/farmacología , Toxoplasma/efectos de los fármacos , Animales , Antiprotozoarios/química , Chlorocebus aethiops , Interacciones Huésped-Parásitos , Microscopía Electrónica de Transmisión , Pruebas de Sensibilidad Parasitaria , Tiazoles/química , Tiosemicarbazonas/química , Toxoplasma/ultraestructura , Células Vero/parasitología
7.
J Environ Radioact ; 77(2): 205-19, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-15312704

RESUMEN

High-resolution gamma spectrometry was used to determine the concentration of 40K, 238U and 232Th series in soil samples taken from areas surrounding the city of Aldama, in Chihuahua. Results of indoor air short-time sampling, with diffusion barrier charcoal detectors, revealed relatively high indoor radon levels, ranging from 29 to 422 Bq/m3; the radon concentrations detected exceeded 148 Bq/m3 in 76% of the homes tested. Additionally, liquid scintillation counting showed concentrations of radon in drinking water ranging from 4.3 to 42 kBq/m3. The high activity of 238U in soil found in some places may be a result of the uranium milling process performed 20 years ago in the area. High radon concentrations indoor and in water may be explained by assuming the presence of uranium-bearing rocks underneath of the city, similar to a felsic dike located near Aldama. The estimated annual effective dose of gamma radiation from the soil and radon inhalation was 3.83 mSv.


Asunto(s)
Contaminantes Radiactivos del Aire/análisis , Radioisótopos de Potasio/análisis , Monitoreo de Radiación , Radón/análisis , Contaminantes Radiactivos del Suelo/análisis , Torio/análisis , Uranio/análisis , Contaminantes Radiactivos del Agua/análisis , Contaminación del Aire Interior/análisis , Humanos , México , Dosis de Radiación , Suelo/análisis , Espectrometría gamma , Abastecimiento de Agua/análisis
8.
Ginecol Obstet Mex ; 67: 295-9, 1999 Jul.
Artículo en Español | MEDLINE | ID: mdl-10496049

RESUMEN

The consensus of the world literature shows that the prematurity is the first cause of perinatal morbidity and mortality. In this period several are the complications to short and long term that they can be presented, but seems be that it is the respiratory distress syndrome (RDS) the principal cause of this problems. This syndrome is frequent in the neonate of mothers with severe preeclampsia of early appearance in which exists the need of interruption the pregnancy. There are some articles, that show that preeclampsia by itself or the steroids given antenatally to the mother may accelerated the fetal lung maturity. The objective of the present study was analyze the behavior of the phospholipids responsible for the fetal lung maturity in amniotic fluid, with the administration of steroids to mothers with preeclampsia, and its correlation with the presentation of the RDS in the RDS in the newborn. 31 patients were included in the study, all of them with severe preeclampsia without complications, between 28 and 33 weeks of pregnancy. Twenty one patients received 12 mg of betametasone i.m. in 2 doses one each day (Group 1) and 10 patients who did not receive the steroid (Group 2). All the births were by cesarean section, amniocentesis was done during this procedure. The relation L/E > or = were observed in 81% of the patients of group 1. In the group 2 the relation L/E < or = 2 were observed in 80% of the cases. The RDS was present in 47% of the neonates in Group 1 and in 100% of the group that did not receive betametasone (p 0.004). The perinatal mortality (20%) was present only in the that did not receive betametasone. The findings of the present paper shows that the administration of betametasone in patients with severe preeclampsia accelerated the fetal lung maturity more the disease in consequence the frequency and severity of the RDS were less.


Asunto(s)
Pulmón/embriología , Preeclampsia/fisiopatología , Enfermedad Aguda , Líquido Amniótico/química , Líquido Amniótico/efectos de los fármacos , Puntaje de Apgar , Betametasona/administración & dosificación , Femenino , Madurez de los Órganos Fetales/efectos de los fármacos , Glucocorticoides/administración & dosificación , Humanos , Recién Nacido , Pulmón/efectos de los fármacos , Masculino , Embarazo , Síndrome de Dificultad Respiratoria del Recién Nacido/prevención & control , Estimulación Química
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