RESUMEN

Among the causes of the nephrotic syndrome in renal allografts, minimal change disease is a rarity with only few cases described in the medical literature. Most cases described have occurred early in the post-transplant course. There is no established treatment for the condition but prognosis is favorable. We describe a case of minimal change disease that developed 8 years after a successful transplantation of a renal allograft in a middle-aged woman. The nephrotic syndrome was accompanied by deterioration of allograft function. Treatment with mycophenolate mofetil was successful in inducing remission and stabilizing allograft function.

Asunto(s)

Fallo Renal Crónico/cirugía , Trasplante de Riñón/patología , Nefrosis Lipoidea/patología , Biopsia , Diagnóstico Diferencial , Femenino , Estudios de Seguimiento , Humanos , Inmunosupresores/uso terapéutico , Glomérulos Renales/patología , Persona de Mediana Edad , Ácido Micofenólico/análogos & derivados , Ácido Micofenólico/uso terapéutico , Nefrosis Lipoidea/sangre , Nefrosis Lipoidea/tratamiento farmacológico , Profármacos , Inducción de Remisión/métodos , Factores de Tiempo , Trasplante Homólogo