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1.
Nat Prod Res ; 33(18): 2600-2608, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29656659

RESUMEN

Cupuassu (Theobroma grandiflorum Schum.) is a popular Amazonian fruit because of its intense aroma and nutritional value, whose lipid fraction is alternatively used in cosmetics. To preserve active principles and ensure their controlled release, extract was microencapsulated by spray drying. Influence of spray-drying conditions on microencapsulation of cupuassu seed by-product extract was investigated according to a 33-Box Behnken factorial design, selecting inlet temperature, maltodextrin concentration and feed flowrate as independent variables, and total polyphenol and flavonoid contents, antiradical power, yields of drying and microencapsulation as responses. Fitting the results by second-order equations and modelling by Response Surface Methodology allowed predicting optimum conditions. Epicatechin and glycosylated quercetin were the major microencapsulated flavonoids. Microparticles showed satisfactory antiradical power and stability at 5 °C or under simulated gastrointestinal conditions, thus they may be used to formulate new foods or pharmaceuticals.


Asunto(s)
Cacao/química , Composición de Medicamentos/métodos , Extractos Vegetales/química , Semillas/química , Desecación , Digestión , Flavonoides/análisis , Hidrólisis , Extractos Vegetales/análisis , Extractos Vegetales/farmacocinética , Polifenoles/análisis , Polisacáridos/química , Quercetina/análisis , Temperatura
2.
Crit Rev Biotechnol ; 35(1): 75-81, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23855523

RESUMEN

Phenolic compounds have recently been recognized for their influence on human metabolism, acting in the prevention of some chronic diseases as well as proving to be important antioxidants in food. Nevertheless, the extraction and concentration processes are usually carried out by organic solvent extraction from natural sources and can generate some drawbacks like phenolic compound degradation, lengthy process times and low yields. As a solution, some eco-friendly technologies, including solid-state fermentation (SSF) or enzymatic-assisted reaction, have been proposed as alternative processes. This article reviews the extraction of phenolic compounds from agro-industrial co-products by solid-state fermentation, even as friendly enzyme-assisted extractions. It also discusses the characteristics of each bioprocess system and the variables that affect product formation, as well as the range of substrates, microorganisms and enzymes that can be useful for the production of bioactive phenolic compounds.


Asunto(s)
Bacterias/enzimología , Bacterias/metabolismo , Fenoles/metabolismo , Agricultura , Antioxidantes/metabolismo , Biotransformación , Residuos
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