RESUMEN
This study is to introduce waste collagen into an unfigured islands-in-sea microfiber nonwoven material, replacing the polyurethane impregnation section of the traditional manufacturing process with the collagen impregnation process. The modified collagen was first impregnated in polyamide/low-density polyethylene (PA/LDPE) fiber nonwoven to form a film. Then the low-density polyethylene component was extracted and dissolved in toluene, resulting in a collagen-based microfiber nonwoven substrate. Waste collagen was first modified to introduce C=C into the molecular chain to obtain vinyl collagen (CMA), and then the following film formation conditions for CMA were studied: 73% degree of substitution (DS), 3 h cross-linking time, and 0.005-0.01 wt % initiator concentration. Then, the preparation of CMA-PA/LDPE and toluene extraction processes were investigated. The optimum toluene extraction conditions were obtained as an extraction temperature of 85 °C and an extraction time of 110 min. The properties of the nonwoven materials were compared before (CMA-PA/LDPE) and after (PA-CMA) extraction. It was found that the homogeneity, tensile strength, and static moisture permeability of the PA-CMA materials prepared by CMA with 50 and 73% DS were all superior to those of PA/LDPE. In particular, the static moisture permeability of PA-CMA (691.6 mg/10 cm2·24 h) increased by 36.2% compared to the microfiber synthetic leather substrate currently in the market. Using scanning electron microscopy (SEM), the continuity of a film of PA-CMA with 73% DS was observed to be better and the fibers were differentiated and relatively tighter fiber-to-fiber gap. The studied novel green process can eliminate the large amount of dimethylformamide (DMF) pollution caused by the current solvent-based polyurethane impregnation process.
RESUMEN
Polybromininated diphenyl ethers (PBDEs) are widely used as flame-retardant additives. Previous studies have demonstrated that PBDEs exposure can lead to neurotoxicity. However, little is known about the effects of PBDE 209 on synaptic plasticity. This study investigated the effect of decabrominated diphenyl ether (PBDE 209), a major PBDEs product, on synaptic plasticity in the dentate gyrus of rats at different developmental periods. We examined the input/output functions, paired-pulse reactions, and the long-term potentiation of the field excitatory postsynaptic potential slope and the population spike amplitude in vivo. Rats were exposed to PBDE 209 during five different developmental periods: pregnancy, lactation via mother's milk, lactation via intragastric administration, after weaning, and prenatal to life. We found that exposed to PBDE 209 during different developmental periods could impair the synaptic plasticity of adult rats in different degrees. The results also showed that PBDE 209 might cause more serious effects on the postsynaptic cell excitability in synaptic plasticity, and the lactation period was the most sensitive time of development towards PBDE 209.