Asunto(s)

Neoplasias Meníngeas/patología , Tumor Rabdoide/patología , Teratoma/patología , Niño , Humanos , Imagen por Resonancia Magnética/métodos , Masculino , Neoplasias Meníngeas/complicaciones , Tumor Rabdoide/complicaciones , Teratoma/complicaciones , Tomógrafos Computarizados por Rayos X

RESUMEN

CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mIns concentration, pointing to gliosis and astrocytic proliferation.

Asunto(s)

Ácido Aspártico/análogos & derivados , Espectroscopía de Resonancia Magnética , Xantomatosis Cerebrotendinosa/metabolismo , Xantomatosis Cerebrotendinosa/patología , Adulto , Ácido Aspártico/metabolismo , Cerebelo/metabolismo , Cerebelo/patología , Colina/metabolismo , Humanos , Inositol/metabolismo , Ácido Láctico/metabolismo , Masculino , Persona de Mediana Edad , Adulto Joven