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1.
Cureus ; 16(1): e51571, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38313940

RESUMEN

This comprehensive document explores the intersection of Sustainable Development Goals (SDGs) and the global transition to renewable energy, with a particular focus on solar energy. The text emphasizes the critical role of reliable and sustainable energy, especially solar power, in achieving health-related SDGs, particularly in low- and middle-income countries (LMICs). It discusses the challenges faced by healthcare facilities in these regions, emphasizing the importance of uninterrupted electricity for critical medical equipment and services. The document highlights the increasing significance of solar energy globally and its potential to address challenges in the healthcare sector. The International Energy Agency's (IEA) estimation that solar photovoltaic (PV) energy has become the cheapest source of electricity is discussed, along with the World Bank's active role in supporting solar energy projects in developing countries. The document presents the current status of solarization, emphasizing the exponential growth of solar capacity and generation. It also discusses global initiatives such as Mission Innovation and the contribution of various international aid organizations, including Sustainable Energy for All (SEforALL), Power Africa, Lighting Global, SolarAid, UNDP - Solar for Health (S4H), and the World Bank. A significant portion of the document focuses on the role of solar energy in healthcare, detailing successful solarization projects in India, sub-Saharan Africa, and other regions. It addresses the challenges of implementing solar PV projects in healthcare facilities, emphasizing the importance of maintenance and proper management. The document also provides insights into the contributions of United Nations Children's Fund (UNICEF) in advancing solar-powered health systems, emphasizing its support to over 80 countries in solarization and off-grid energy solutions for healthcare. In conclusion, this article emphasizes the need for collaboration among international aid organizations, governments, and development partners to ensure universal access to reliable and sustainable electricity, particularly in healthcare facilities. It underscores the importance of long-term planning, sustainability, innovative business models, and awareness campaigns to achieve scalable and impactful results in the intersection of solar energy and healthcare delivery.

2.
Indian J Exp Biol ; 43(12): 1156-60, 2005 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-16359127

RESUMEN

The ethanolic extracts, various fractions and two pure compounds isolated from the plant N. arbortris were tested against Encephalomyocarditis Virus (EMCV) and Semliki Forest Virus (SFV). Pronounced in vitro virus inhibitory activity was observed with the ethanolic and n-butanol fractions as well as with the pure compounds arbortristoside A and arbortristoside C. In addition, ethanolic extracts and n-butanol fraction protected EMCV infected mice to the extent of 40 and 60% respectively against SFV at a daily dose of 125 mg/kg body weight.


Asunto(s)
Virus de la Encefalomiocarditis/efectos de los fármacos , Oleaceae , Semillas , Virus de los Bosques Semliki/efectos de los fármacos , 1-Butanol/administración & dosificación , 1-Butanol/farmacología , Administración Oral , Infecciones por Alphavirus/tratamiento farmacológico , Infecciones por Alphavirus/mortalidad , Animales , Infecciones por Cardiovirus/tratamiento farmacológico , Infecciones por Cardiovirus/mortalidad , Chlorocebus aethiops , Relación Dosis-Respuesta a Droga , Glicósidos/administración & dosificación , Glicósidos/farmacología , Inyecciones Intraperitoneales , Iridoides/administración & dosificación , Iridoides/farmacología , Ratones , Fitoterapia/métodos , Extractos Vegetales/farmacología , Células Vero
3.
J Ethnopharmacol ; 71(1-2): 89-92, 2000 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-10904150

RESUMEN

Products of certain plants given to mothers after child birth or to invalids were studied for immunostimulant activity using the macrophage migration index (MMI) as a parameter of macrophage activation and cell-mediated immunity and haemagglutinating antibody (HA) titres and plaque-forming cell (PFC) counts as parameters of humoral immunity. Feeding of Prunus amygdalus (Almond(1)) and Buchanania lanzan (Chirronji(1)) significantly stimulated both CMI and humoral immunity in BALB/c mice as evidenced by the enhancement of MMI, HA titres, and PFC counts. Euryale ferox (Tel makhana(1)), Phoenix dactylifera (Chhohara(1)) and Zingiber officinale (Sonth(1)), however, stimulated humoral immunity to a greater extent than CMI. The observation provides scientific basis for feeding the products of above plants to mothers after child birth and to invalids with a relatively poor immune status.


Asunto(s)
Adyuvantes Inmunológicos/farmacología , Frutas/química , Medicina Ayurvédica , Plantas Medicinales/química , Animales , Inhibición de Migración Celular , Femenino , Hemaglutininas/análisis , Técnica de Placa Hemolítica , India , Trabajo de Parto , Masculino , Ratones , Ratones Endogámicos BALB C , Extractos Vegetales/química , Extractos Vegetales/farmacología , Embarazo
4.
Indian J Matern Child Health ; 10(1): 13-5, 1999.
Artículo en Inglés | MEDLINE | ID: mdl-12295282

RESUMEN

PIP: This study was conducted during 1991-93 to determine the effects of various maternal factors on fetal birth weight. 219 pregnant women aged 15-44 years and their children participated. Data pertaining to maternal and fetal anthropometry were collected. Results revealed that birth weight seemed to be affected by many variables. Maternal height could affect fetal weight either genetically or by environmental mechanism. It was also observed that the mean birth weight increased significantly with increasing maternal prepregnancy weight and height. In addition, maternal weight gain during pregnancy was a major determinant of fetal outcome and was found to be a primary indicator of infant morbidity and mortality. Newborn infants with birth weights of 2500 g and gestational ages of more than 34 weeks had a 99.8% survival rate, whereas babies born earlier than 26 weeks of gestation usually did not survive. In general, maternal prepregnancy weight and weight gain during pregnancy (P 0.0001) had a greater effect on birth weight than did maternal height and gestational age (P 0.01).^ieng


Asunto(s)
Peso al Nacer , Estatura , Peso Corporal , Edad Gestacional , Lactante , Resultado del Embarazo , Embarazo , Mujeres , Adolescente , Factores de Edad , Asia , Biología , Demografía , Países en Desarrollo , Feto , India , Fisiología , Población , Características de la Población , Reproducción
5.
Neurol India ; 46(4): 316-318, 1998.
Artículo en Inglés | MEDLINE | ID: mdl-29508831

RESUMEN

Adult presentation in diastematomyelia is very rare. The common location is from first to third lumbar vertebrae. Lumbosacral adult diastematomyelia is even rarer. A 42 years male with lumbosacral diastematomyelia is described. Combined myelographic-CT scan study demonstrated lumbar canal stenosis and bony spur attached to vertebral bodies of the fifth lumbar and first sacral vertebra. Surgery with decompression of neural elements and removal of bony spur resulted in complete relief of symptoms. Detailed case representation and a review of 74 cases of adult diastematomyelia is reported.

6.
Neurol India ; 43(3): 168-170, 1995.
Artículo en Inglés | MEDLINE | ID: mdl-29542516

RESUMEN

Corpus callossal lipoma is a rare benign congenital disorder. These lesions may be associated with various congenital and acquired disorders. Lipoma of the corpus callosum with frontal encephalocele has not been described in the literature so far. We are reporting one such case and the relevant literature is reviewed.

7.
Neurol India ; 43(3): 161-164, 1995.
Artículo en Inglés | MEDLINE | ID: mdl-29542514

RESUMEN

Primary spinal melanoma is uncommon, with only 36 cases reported in the available literature. These lesions usually occur as diffuse melanomatosis. Solitary lesions are rare. Extradural locations is extremely rare, with only tow case reports in the literature. One such patient is reported and relevant literature reviewed.

8.
J Ethnopharmacol ; 42(1): 31-7, 1994 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-8046941

RESUMEN

Nyctanthes arbor-tristis L. (Oleaceae), a plant widely used in the traditional medicinal systems of India, has recently been reported to possess hepatoprotective, antileishmanial, antiviral and antifungal activities. In the present study strong stimulation of antigen specific and non-specific immunity, as evidenced by increases in humoral and delayed type hypersensitivity (DTH) response to sheep red blood cells (SRBC) and in the macrophage migration index (MMI), has been demonstrated in mice fed with 50% ethanolic extract of seeds, flowers and leaves of this plant. Maximum activity was found in the seeds in which the active principle(s) appear to be mainly associated with lipids. In flowers and leaves, however, the major activity was found in the aqueous fraction of the 50% ethanol extract. The immunostimulant substance(s) found in N. arbor-tristis L. are likely to play a role in its antiamoebic, antileishmanial, antiviral and certain other activities.


Asunto(s)
Adyuvantes Inmunológicos/farmacología , Extractos Vegetales/farmacología , Administración Oral , Animales , Formación de Anticuerpos/efectos de los fármacos , Inhibición de Migración Celular , Eritrocitos/inmunología , Etanol , Femenino , Pruebas de Hemaglutinación , Hipersensibilidad Tardía/inmunología , Masculino , Ratones , Ratones Endogámicos BALB C , Plantas Medicinales , Ovinos
9.
J Nat Prod ; 56(7): 995-9, 1993 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-8377022

RESUMEN

EtOH extract and purified diterpene andrographolides of Andrographis paniculata (Acanthaceae) induced significant stimulation of antibody and delayed type hypersensitivity (DTH) response to sheep red blood cells (SRBC) in mice. The plant preparations also stimulated nonspecific immune response of the animals measured in terms of macrophage migration index (MMI) phagocytosis of 14C-leucine labelled Escherichia coli and proliferation of splenic lymphocytes. The stimulation of both antigen specific and nonspecific immune response was, however, of lower order with andrographolide than with the EtOH extract, suggesting thereby that substance(s) other than andrographolide present in the extract may also be contributing towards immunostimulation.


Asunto(s)
Adyuvantes Inmunológicos/farmacología , Diterpenos/farmacología , Plantas Medicinales/química , Adyuvantes Inmunológicos/administración & dosificación , Adyuvantes Inmunológicos/aislamiento & purificación , Administración Oral , Animales , Diterpenos/administración & dosificación , Diterpenos/aislamiento & purificación , Eritrocitos/inmunología , Femenino , Pruebas de Hemaglutinación , Técnica de Placa Hemolítica , Hipersensibilidad Tardía/inmunología , India , Inyecciones Intraperitoneales , Activación de Linfocitos/efectos de los fármacos , Macrófagos/efectos de los fármacos , Macrófagos/inmunología , Masculino , Ratones , Ratones Endogámicos BALB C , Fagocitosis/efectos de los fármacos , Extractos Vegetales/administración & dosificación , Extractos Vegetales/farmacología , Ovinos/inmunología
10.
Indian Pediatr ; 30(6): 765-9, 1993 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-8132256

RESUMEN

Out of 5031 children admitted to S.N. Hospital, Agra during one year, there were 716 cases (14.2%) of accidents. Most cases were in the age group of 4-9 years; boys were affected more commonly than girls. The maximum cases occurred due to fall (44.4%), followed by road traffic accidents (26.4%) and burns (11.5%). The consequences in terms of morbidity and mortality was also high. Kerosene oil ingestion was the most common encountered form of poisoning. Incriminating environmental factors could be identified in 51.8% cases and included poorly protected roofs (23.7%), poor state of roads (10.0%), defective vehicles (7.5%), and houses opening directly on the streets (7.3%). More than half of the accidents took place at home (58.7%), followed by those on streets (30.3%) or at farmhouses (57%). Injuries caused by sharp and blunt objects were more common in villages. Only 21.4% children had received first aid, often by the family, before reaching the hospital. The overall mortality rate was 53.1/1000, but in cases of burns the mortality was (146.3/1000). This study suggests that falls and traffic accidents have the highest incidence and mortality in childhood accidents and modification of the home environment can be an effective measure to prevent such incidents.


Asunto(s)
Accidentes/estadística & datos numéricos , Hospitalización/estadística & datos numéricos , Vigilancia de la Población , Heridas y Lesiones/epidemiología , Accidentes/mortalidad , Distribución de Chi-Cuadrado , Niño , Preescolar , Femenino , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Estudios Prospectivos , Factores de Riesgo , Distribución por Sexo , Heridas y Lesiones/etiología
11.
Mutat Res ; 283(4): 233-5, 1992 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-1383794

RESUMEN

Sister-chromatid exchange (SCE) frequency has been studied from peripheral blood lymphocyte cultures of 21 patients with epilepsy on sodium valproate, 20 patients who had not started therapy (untreated) and 20 normal healthy controls. Treated and untreated patients with epilepsy were observed to have higher SCE frequencies (mean 9.05 and 9.82 respectively) than healthy controls (mean 4.8; P < 0.001). There was no significant difference in SCE frequency between treated and untreated patients. This suggests that the disease itself may be associated with an increased frequency of SCEs.


Asunto(s)
Epilepsia/genética , Mutágenos/toxicidad , Intercambio de Cromátides Hermanas , Ácido Valproico/toxicidad , Adolescente , Adulto , Anciano , Análisis de Varianza , Niño , Epilepsia/tratamiento farmacológico , Humanos , Leucocitos/citología , Leucocitos/efectos de los fármacos , Persona de Mediana Edad , Ácido Valproico/uso terapéutico
12.
Indian J Med Res ; 96: 302-5, 1992 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-1459674

RESUMEN

The mutagenic potential of phenytoin (PHT) was studied using the sister chromatid exchange (SCE) assay. Twenty nine PHT treated epileptics, 32 untreated and 32 normal healthy controls were analysed. Similar SCE frequencies were observed in untreated patients and patients on PHT monotherapy. Both groups had significantly increased SCE frequency as compared to controls. No positive correlation of SCE frequency with sex and duration of therapy was observed. The results of the present study suggest the role of the disease condition in inducing genetic damage as assessed by increased SCE frequencies.


Asunto(s)
Epilepsia/genética , Fenitoína/efectos adversos , Intercambio de Cromátides Hermanas/efectos de los fármacos , Adolescente , Adulto , Epilepsia/tratamiento farmacológico , Femenino , Humanos , Masculino , Pruebas de Mutagenicidad , Fenitoína/uso terapéutico
13.
Indian J Public Health ; 35(4): 113-6, 1991.
Artículo en Inglés | MEDLINE | ID: mdl-1821883

RESUMEN

The study was conducted to identify some of the managerial gaps that affect utilization of Antenatal services. Fifty two women aged 15-39 yrs., drawn from 22 households were studied in depth. This article identifies some of the demographic and socio-cultural factors affecting utilization pattern. The degree of utilization was significantly related to education of the woman and her husband's occupation, caste, parity and cultural factors. All women lived within 1 Km from the Health Centre, did not use the services at all, thereby indicating the presence of other factors influencing their attitude towards use of services.


Asunto(s)
Servicios de Salud Materna/organización & administración , Atención Prenatal , Población Rural , Cultura , Demografía , Escolaridad , Femenino , Humanos , India , Servicios de Salud Materna/provisión & distribución , Ocupaciones , Embarazo , Factores Socioeconómicos
14.
J Nat Prod ; 54(4): 1102-4, 1991.
Artículo en Inglés | MEDLINE | ID: mdl-1791475

RESUMEN

Iridoid glucosides (arbortristosides A [I], B [2], C [3], and 6beta-hydroxy-loganin [4] isolated from the traditional plant Nyctanthes arbortristis show antileishmanial activity in both in vitro (against amastigotes in macrophage cultures) and in vivo (in hamsters) test systems.


Asunto(s)
Antiprotozoarios , Glucósidos/farmacología , Leishmania donovani/efectos de los fármacos , Leishmaniasis Visceral/tratamiento farmacológico , Plantas Medicinales , Piranos/farmacología , Animales , Antiprotozoarios/química , Antiprotozoarios/aislamiento & purificación , Cricetinae , Glucósidos/aislamiento & purificación , Masculino , Mesocricetus , Estructura Molecular , Piranos/aislamiento & purificación , Sigmodontinae
16.
J Inorg Biochem ; 39(3): 237-45, 1990 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-2203880

RESUMEN

Synthetic, structural and biochemical aspects of some organoboron complexes of sulphur containing ligands having ONS and SNNS donor systems have been described. The ligands were prepared by the condensation of 1-phenyl-1,3-butanedione, 2,4-pentanedione, diphenylethanedione, 2,3-butanedione, ethanedial and 1,4-benzenedialdehyde with 2-mercaptoaniline. The unimolar reactions between phenylboronic acid and these thio-ligands have produced Ph.B (ONS) and Ph.B. (SNNS) type of biologically active complexes. These have been characterized by elemental analysis, molecular weight determinations, and conductivity measurements. Based on UV, IR, 1H NMR, 13C NMR and 11B NMR spectral studies, a tetracoordinated state of boron has been established in all the derivatives. The ligands and their corresponding organoboron complexes have been tested in vitro against a number of pathogenic fungi and bacteria and found to possess remarkable fungicidal and bactericidal properties.


Asunto(s)
Antiinfecciosos , Antifúngicos , Boro/farmacología , Azufre/farmacología , Antibacterianos , Candida albicans/efectos de los fármacos , Fenómenos Químicos , Química , Escherichia coli/efectos de los fármacos , Lactobacillus/efectos de los fármacos , Ligandos , Espectroscopía de Resonancia Magnética , Staphylococcus aureus/efectos de los fármacos
17.
J Inorg Biochem ; 38(1): 57-67, 1990 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-2332764

RESUMEN

Synthesis, characterization, and structural aspects of a new class of dioxomolybdenum(VI) complexes with biologically active benzothiazolines, 2-(2-pyridyl) benzothiazoline, 2-(2-thienyl) benzothiazoline, 2-(2-furyl) benzothiazoline, 2-(3-indolyl) benzothiazoline, glyoxal benzothiazoline, biacetylbenzothiazoline, benzil benzothiazoline, and terphthaldehyde benzothiazoline have been described. The newly synthesized complexes, [MoO2(Bzt)2] and [MoO2(Bzt')] (where BztH and Bzt'H2 represent benzothazoline molecules) have been characterized by elemental analysis, conductance measurements, molecular weight determinations, and magnetic studies. Based on IR, 1H NMR, 13C NMR, and electronic spectral studies, distorted octahedral geometry with cis-MoO2 group has been indicated for the resulting complexes. Two benzothiazolines and their corresponding metal complexes were screened for their antifungicidal and antibacterial activity on several fungi and bacteria and found to be quite active in this respect. In addition, antifertility activity of representative ligands and their molybdenum complexes was also evaluated and discussed in male mice.


Asunto(s)
Antibacterianos , Antifúngicos , Fertilidad/efectos de los fármacos , Molibdeno/farmacología , Compuestos Organometálicos/farmacología , Tiazoles/farmacología , Animales , Fenómenos Químicos , Química , Espectroscopía de Resonancia Magnética , Masculino , Ratones , Estructura Molecular , Compuestos Organometálicos/síntesis química , Análisis Espectral , Recuento de Espermatozoides , Motilidad Espermática/efectos de los fármacos , Tiazoles/síntesis química
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