RESUMEN
PURPOSE: To describe visual performance in high myopia. METHODS: In this cross-sectional study, 148 emmetropes [spherical equivalent (SE) - 0.50 to + 1.00 D] and 564 high myopes [SE ≤ - 6.00 D] were categorised into three groups (Group 1: SE - 6.00 to > - 8.00 D; Group 2: SE - 8.00 to > - 10.00 D; and Group 3: SE ≤ - 10.00 D). Multivariate regression analyses adjusting for age and ethnicity examined the relationship between corrected distance visual acuity (CDVA) [photopic, mesopic and super vision test-night vision goggles (SVT-NVG)] and contrast sensitivity (CS)] (mesopic and SVT-NVG) with SE and axial length (AL). RESULTS: Mean age of subjects was 21.07 ± 1.17 years, and majority were Chinese (91.9%). Mean SE was 0.10 ± 0.23 D (emmetropes) and - 8.76 ± 2.04 D (high myopes), p < 0.001. Higher degrees of myopia were associated with reduced CDVA and CS, and increased AL (all p < 0.001). Among high myopes, Group 1 had the highest proportion of subjects with good CDVA (photopic ≤ 0.00 LogMAR, mesopic ≤ 0.00 LogMAR and NVG ≤ 0.10 LogMAR) and CS (mesopic ≥ 0.75 LogCS and NVG ≥ 0.35 LogCS) compared with Groups 2 and 3 (all p < 0.001). Among high myopes with good VA (photopic ≤ 0.00 LogMAR, mesopic ≤ 0.00 LogMAR and NVG ≤ 0.10 LogMAR), Group 1 also had the highest proportion of subjects who achieved mesopic ≥ 0.75 LogCS and NVG ≥ 0.35 LogCS (both p < 0.001). Multivariate analyses demonstrated that reduced VA and CS were associated with decreased SE and increased AL (all p < 0.001). CONCLUSIONS: High myopia is associated with reduced VA and reduced CS.
Asunto(s)
Miopía , Adulto , Sensibilidad de Contraste , Estudios Transversales , Humanos , Miopía/diagnóstico , Refracción Ocular , Pruebas de Visión , Agudeza Visual , Adulto JovenRESUMEN
Diabetic retinopathy and diabetic macular edema (DME) are leading causes of blindness throughout the world, and cause significant visual morbidity. Ocular imaging has played a significant role in the management of diabetic eye disease, and the advent of advanced imaging modalities will be of great value as our understanding of diabetic eye diseases increase, and the management options become increasingly varied and complex. Color fundus photography has established roles in screening for diabetic eye disease, early detection of progression, and monitoring of treatment response. Fluorescein angiography (FA) detects areas of capillary nonperfusion, as well as leakage from both microaneurysms and neovascularization. Recent advances in retinal imaging modalities complement traditional fundus photography and provide invaluable new information for clinicians. Ultra-widefield imaging, which can be used to produce both color fundus photographs and FAs, now allows unprecedented views of the posterior pole. The pathologies that are detected in the periphery of the retina have the potential to change the grading of disease severity, and may be of prognostic significance to disease progression. Studies have shown that peripheral ischemia may be related to the presence and severity of DME. Optical coherence tomography (OCT) provides structural detail of the retina, and the quantitative and qualitative features are useful in the monitoring of diabetic eye disease. A relatively recent innovation, OCT angiography, produces images of the fine blood vessels at the macula and optic disc, without the need for contrast agents. This paper will review the roles of each of these imaging modalities for diabetic eye disease.