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Indian J Lepr ; 82(2): 85-9, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-21434511

RESUMEN

Atypical presentations can be expected when leprosy, a mycobacterial disease is associated with HIV. We report a case of a 28 year old male driver with a high risk behavior, who came for evaluation of hypoaesthetic, scaly erythematous plaques over face, trunk, upper extremity; verrucous lesions over elbows and necrotic lesions over the neck and lower extremities since 6 months. No other systemic complaints were present. Nerve examination showed grossly thickened left greater auricular nerve and cord like thickening of bilateral ulnar and lateral popliteal nerves. His investigations revealed anemia, a reactive ELISA for HIV-1 and CD4 of 400 cell/cmm. Ultrasonography of the thickened nerves revealed an abscess in the left ulnar nerve whereas the left greater auricular nerve showed neuritis. Histopathology from an erythematous plaque was suggestive of borderline tuberculoid leprosy in reaction. Final diagnosis was borderline tuberculoid leprosy in type 1 reaction with atypical and varied morphology in an immunocompromised male with neuritis of the left greater auricular nerve, a silent left ulnar nerve abscess with early left ulnar nerve palsy. Our case highlights the atypical morphology of leprosy lesions and the unexpected protective cellular response as suggested by formation of nerve abscess in a HIV positive patient.


Asunto(s)
Infecciones por VIH/complicaciones , VIH-1/aislamiento & purificación , Lepra Dimorfa/diagnóstico , Lepra Tuberculoide/diagnóstico , Nervios Periféricos/patología , Absceso/complicaciones , Absceso/patología , Adulto , Diagnóstico Diferencial , Infecciones por VIH/diagnóstico , Infecciones por VIH/patología , VIH-1/inmunología , Humanos , Lepra Dimorfa/complicaciones , Lepra Dimorfa/patología , Lepra Tuberculoide/complicaciones , Lepra Tuberculoide/patología , Masculino , Neuritis/complicaciones , Neuritis/patología , Nervios Periféricos/diagnóstico por imagen , Piel/patología , Nervio Cubital/patología , Ultrasonografía
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