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1.
Artículo en Inglés | MEDLINE | ID: mdl-38791761

RESUMEN

BACKGROUND: Women and girls account for more than 50% of the global HIV population. In Nigeria, the proportion of women living with HIV on long-term antiretroviral therapy (ART) has been on the rise. Despite this, little research exists on their experiences regarding antiretroviral therapy use, especially for women living with HIV (WLHIV) in Plateau State, Nigeria. This study investigates the barriers and facilitators influencing antiretroviral therapy use among women living with HIV. METHODS: This study employed a qualitative research design, using focus groups, and included women (female sex workers, pregnant and non-pregnant women living with HIV) and the male partners of serodiscordant couples. Eligibility criteria were being 18 years of age or older, on antiretroviral therapy for more than one year/on pre-exposure prophylaxis (PrEP) for more than one month, and speaking English, Hausa, or both. Data coding utilized both inductive and deductive approaches, and standard content analysis was applied to develop emerging themes. RESULTS: Of the 106 participants, 88 were women living with HIV, and 18 were men in serodiscordant couples. The first facilitator shared by the participants was feeling healthier and stronger due to the antiretroviral therapy, which was also expressed by the male participants on PrEP as feeling good while taking the drug. Additional facilitators shared by the participants included weight gain and having a more positive outlook on life. Participants also disproportionately described barriers to using antiretroviral therapy, including experiences with emotional challenges, physical discomfort, and side effects of ART. Such barriers were linked to feelings of past regret, frustration, and disappointment. CONCLUSION: This study underscores the significance of maintaining a positive perspective on ART use, demonstrated by the connection between a positive outlook and weight gain, and highlights the hurdles that Plateau State's women living with HIV face in adhering to antiretroviral therapy. Policymakers and healthcare providers can utilize these findings to formulate targeted strategies aimed at minimizing identified barriers and enhancing antiretroviral therapy utilization among this population via peer- support groups, economic empowerment, and psychosocial support.


Asunto(s)
Infecciones por VIH , Humanos , Nigeria , Femenino , Infecciones por VIH/tratamiento farmacológico , Infecciones por VIH/psicología , Adulto , Masculino , Persona de Mediana Edad , Adulto Joven , Grupos Focales , Antirretrovirales/uso terapéutico , Fármacos Anti-VIH/uso terapéutico , Embarazo
2.
Sci Robot ; 9(86): eadi2746, 2024 Jan 17.
Artículo en Inglés | MEDLINE | ID: mdl-38232146

RESUMEN

Versatile programmable materials have long been envisioned that can reconfigure themselves to adapt to changing use cases in adaptive infrastructure, space exploration, disaster response, and more. We introduce a robotic structural system as an implementation of programmable matter, with mechanical performance and scale on par with conventional high-performance materials and truss systems. Fiber-reinforced composite truss-like building blocks form strong, stiff, and lightweight lattice structures as mechanical metamaterials. Two types of mobile robots operate over the exterior surface and through the interior of the system, performing transport, placement, and reversible fastening using the intrinsic lattice periodicity for indexing and metrology. Leveraging programmable matter algorithms to achieve scalability in size and complexity, this system design enables robust collective automated assembly and reconfiguration of large structures with simple robots. We describe the system design and experimental results from a 256-unit cell assembly demonstration and lattice mechanical testing, as well as a demonstration of disassembly and reconfiguration. The assembled structural lattice material exhibits ultralight mass density (0.0103 grams per cubic centimeter) with high strength and stiffness for its weight ( 11.38 kilopascals and 1.1129 megapascals, respectively), a material performance realm appropriate for applications like space structures. With simple robots and structure, high mass-specific structural performance, and competitive throughput, this system demonstrates the potential for self-reconfiguring autonomous metamaterials for diverse applications.

3.
Poult Sci ; 102(8): 102723, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37406598

RESUMEN

The poultry industry has not been spared from the prevalent incidence of diseases caused by invasive pathogens, especially Salmonella. Due to the pressing need to identify a suitable antibiotic alternative for use in poultry production, this study investigated the efficacy of red osier dogwood (ROD) extract on the growth, blood parameters, gut morphology, and Salmonella excretion in broiler chickens orally challenged with Salmonella Enteritidis (SE). A 4 × 2 factorial experiment was conducted based on 2 main factors, namely dietary treatments, and SE challenge. A total of 404, one-day-old male Ross broiler chicks were randomly assigned to 4 dietary treatments; 1) Negative control (NC), 2) NC + 0.075 ppm of Trimethoprim-sulfadiazine (TMP/SDZ)/kg of diet, 3) NC + 0.3% ROD extract, and 4) NC + 0.5% ROD extract. The absence of SE in the fecal samples obtained from chick delivery boxes was confirmed on d 0. On d 1, half of the birds were orally gavaged with 0.5 mL of phosphate-buffered saline each (noninfected group) and the remaining with 0.5 mL of 3.1 × 105 CFU/mL SE (infected group) in all treatment groups. Dietary treatments were randomly assigned to 8 replicate cages at 6 birds/cage. On 1-, 5-, 12-, and 18-day postinfection (DPI), cloacal fecal samples were collected on the 6 birds/cage to assess SE excretion. Average weight gain (AWG), average feed intake (AFI), feed conversion ratio (FCR), and mortality were determined weekly. On d 21, 10 chickens/treatment were euthanized to perform hematology, gut histomorphometry, serum immunoglobulins G and M (IgG and IgM), and superoxide dismutase measurements. Both ROD extract levels did not affect (P > 0.05) growth performance; however, the SE-infected birds showed increased (P < 0.05) AFI and FCR throughout the experimental period. Regardless of the SE-infection, both ROD extract levels improved (P < 0.05) duodenal villus height: crypt depth compared to other treatments. 0.5% ROD extract improved (P < 0.05) ileal villus width (VW) of noninfected birds and ileal crypt depth of infected birds, but it decreased (P < 0.05) the ileal VW of infected birds, compared to other treatments. The SE-infected birds showed lower (P < 0.05) lymphocytes (L) but increased (P < 0.05) heterophils (H), H:L, and monocytes (MON). Both ROD extract levels did not affect (P > 0.05) white blood cell differential, while dietary 0.3% ROD extract increased (P < 0.05) MON of the birds, regardless of infection model. Regardless of infection model, both TMP/SDZ and 0.5% ROD extract reduced the concentration of IgM in the serum, compared to the control and 0.3% ROD (P = 0.006). Conclusively, both ROD extract levels improved duodenal histomorphology and body defense against SE infection in broiler chickens; however, the 0.3% ROD extract was better.


Asunto(s)
Cornus , Enfermedades de las Aves de Corral , Salmonelosis Animal , Animales , Masculino , Pollos , Salmonella enteritidis , Trimetoprim , Sulfadiazina , Dieta/veterinaria , Inmunoglobulina M , Alimentación Animal/análisis , Enfermedades de las Aves de Corral/tratamiento farmacológico , Suplementos Dietéticos , Salmonelosis Animal/tratamiento farmacológico
4.
Poult Sci ; 102(4): 102550, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-36854216

RESUMEN

With the subsisting restrictions on the use of antibiotics in poultry production, the use of plant extracts has shown some promising antimicrobial capacity similar to antibiotics; however, such capacity is largely dependent on their total polyphenol concentration and profile. Given the emerging antimicrobial potential of red osier dogwood (ROD) extract, the study aimed to investigate the pharmacodynamic effect of ROD extract on the ileal and cecal microbiota of broiler chickens challenged orally with Salmonella Enteritidis (SE). A 21 d 4 × 2 factorial experiment was conducted based on 2 main factors, including diets and SE challenge. A total of 384 one-day-old mixed-sex Cobb-500 broiler chicks were randomly allotted to 4 dietary treatments; Negative control (NC), NC + 0.075 mg trimethoprim-sulfadiazine (TMP/SDZ)/kg of diet, and NC containing either 0.3 or 0.5% ROD extract. On d 1, half of the birds were orally challenged with 0.5 mL of phosphate-buffered saline (Noninfected group) and the remaining half with 0.5 mL of 3.1 × 105 CFU/mL SE (Infected group). Dietary treatments were randomly assigned to 8 replicate cages at 6 birds/cage. On d 21, 10 birds/treatment were euthanized and eviscerated to collect ileal and cecal digesta for gut microbiota analysis. The ileal and cecal microbiota was dominated by phyla Firmicutes, Proteobacteria, and Actinobacteriota. The SE infection decreased (P < 0.05) the relative abundance of Proteobacteria and Actinobacteriota in the ileum and ceca, respectively, however, it increased (P < 0.05) Proteobacteria in the ceca. Both 0.3 and 0.5% ROD extracts (P < 0.05) depressed the relative abundance of Actinobacteriota in the ileum but marginally improved (P < 0.05) it in the ceca compared to the TMP/SDZ treatment. Dietary TMP/SDZ increased (P < 0.05) genus Bifidobacterium at the ileal and cecal segments compared to other treatments. Dietary 0.3 and 0.5% marginally improved (P < 0.05) Bifidobacterium in the ceca and depressed (P < 0.05) Weissella and was comparably similar to TMP/SDZ in the ileum. Regardless of the dietary treatments and SE infection, alpha diversity differed (P < 0.05) between ileal and cecal microbiota. Beta diversity was distinct (P < 0.05) in both ileal and cecal digesta along the SE infection model. Conclusively, both ROD extract levels yielded a pharmacodynamic effect similar to antibiotics on ileal and cecal microbiota.


Asunto(s)
Microbioma Gastrointestinal , Extractos Vegetales , Sulfadiazina , Trimetoprim , Animales , Antibacterianos/farmacología , Ciego/efectos de los fármacos , Ciego/microbiología , Pollos/microbiología , Cornus , Dieta/veterinaria , Íleon/efectos de los fármacos , Íleon/microbiología , Salmonella enteritidis/efectos de los fármacos , Sulfadiazina/farmacología , Trimetoprim/farmacología , Extractos Vegetales/farmacología , Combinación de Medicamentos , Microbioma Gastrointestinal/efectos de los fármacos , Masculino , Femenino
5.
Dialogues Health ; 2: 100105, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38515464

RESUMEN

Background: The attendant long-term mental health consequence of the conflict of various kinds in Nigeria is yet to be thoroughly investigated. The Tiv-Fulani farmer-herdsmen crisis is one such conflict that occurred in 2013/2014 in Guma local government in Benue state. Aims: This study seeks to find out some years after the crisis, the prevalence difference in posttraumatic stress disorder (PTSD) between a community (Uikpiam) with direct exposure to the conflict and another (Daudu) with indirect exposure, the pattern of distribution of PTSD symptoms and the associate factors of PTSD. Methods: It is a cross-sectional one that employed a multi-stage cluster sampling method to select 413 participants; 135 from Uikpiam and 278 from Daudu. The study instruments administered included a questionnaire with some socio-demographic variables and an extract from the PTSD module of the Composite International Diagnostic Interview. Results: The prevalence rate of PTSD was higher in Uikpiam (16.3%) when compared to Daudu (4.3%). A high proportion of sub-threshold symptoms of PTSD was recorded in both communities. An association was found between a lower educational qualification and PTSD (χ2 = 8.373; p = 0.039). Conclusion: PTSD can be a prolonged mental ill-effect of crisis and proximity to trauma sites increases vulnerability including lower education. This study looked at PTSD only as an outcome of this crisis, but mental health adverse outcomes of the crisis may not be limited to this alone, hence the need for further investigations for relevant stakeholders to act.

6.
Ann Ib Postgrad Med ; 21(3): 39-45, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-38706621

RESUMEN

Objective: To compare the effectiveness of sodium perborate mixed with distilled water and sodium perborate mixed with 30% hydrogen peroxide as non-vital bleaching agent of anterior discolored teeth. Materials and methods: A randomized controlled trial was undertaken among 61 patients who presented with 70 discolored anterior teeth at the Conservative and Family Dentistry Clinics of the University College Hospital, Ibadan, Nigeria. The 70 teeth were randomly allocated into two groups of treatments. In Group A, the test group, the coronal part of endodontically treated teeth was further treated with sodium perborate mixed with distilled water while group B, the control group, the coronal part of endodontically treated teeth were also further treated with sodium perborate mixed with 30% hydrogen peroxide. Information on study participants biodata and satisfaction with treatment were obtained. Tooth shade assessment was done using shade guide units of the vitapan shade guide at baseline and during recall visits on days 7, 14, and 21. Frequencies, means, and standard deviations were generated. The Chi-squared test was used to determine the association between two categorical variables at p < 0.05. Results: In the control group, the mean ± SD tooth shade was 12.5 ± 3.2, 8.7 ± 3.8, 4.9 ± 2.8, and 3.1 ± 2.2 at baseline, Day 7, Day 14, and Day 21, respectively. In the test group, the corresponding values were 12.8 ± 3.2, 9.6 ± 3.9, 5.6 ± 3.0, and 4.0 ± 2.9. The mean ± SD tooth shade scores of the control and test groups were 12.5 ± 3.2 and 12.8 ± 3.2, respectively (p = 0.15). Twenty-two (62.9%) and 19 (54.3%) of the study participants in the control and test groups, respectively, reported that they were extremely satisfied (p = 0.60). Conclusion: The effectiveness of sodium perborate mixed with distilled water and sodium perborate mixed with 30% hydrogen peroxide in lightening the coronal part of endodontically treated non-vital discolored anterior teeth was similar. Both bleaching agents demonstrated similar patient satisfaction.

7.
Anim Nutr ; 9: 357-377, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35600557

RESUMEN

The ever-growing human population, coupled with the exigent need to meet the increasing demand for poultry meat and egg, has put the onus on poultry nutritionists and farmers to identify alternative feed ingredients that could assure the least-cost feed formulation. In addition, the public desire for non-antibiotic-treated poultry products has also necessitated the ultimate search for potent antibiotic alternatives for use in poultry production. While some identified alternatives are promising, their cost implications and technical know-how requirements may discourage their ease of adoption in poultry. The use of plants and/or their by-products, like fruit pomaces, present a pocket-friendly advantage and as a result, are gaining much interest. This is traceable to their rich phytochemical profile, nutritional composition, ready availability, and relatively cheap cost. The fruit juice and wine pressing industries generate a plethora of fruit wastes annually. Interestingly, fruit pomaces contain appreciable dietary fibre, protein, and phenolic compounds, and thus, their adoption could serve the poultry industry in dual capacities including as substitutes to antibiotics and some conventional feedstuff. Thus, there is a possibility to reduce fruit wastes produced and feed-cost in poultry farming from environmental and economical standpoints, respectively. This review seeks to provide reinforcing evidence on the applicability and impact of fruit pomaces in poultry nutrition.

8.
Poult Sci ; 101(7): 101861, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-35544959

RESUMEN

As we advance in the search for antibiotic-alternatives, harnessing plant materials with high total polyphenol concentration (TPC) would be quintessential. Given the high TPC in red osier dogwood (ROD) extract, the current study aimed to determine its efficacy on the growth performance, intestinal health, blood biochemistry, and antioxidant capacity of broiler chickens. A 21-day 4x2 factorial feeding trial was conducted based on two main factors namely, dietary treatments and Salmonella Enteritidis Lipopolysaccharides SE-LPS) challenge. A total of 384 one-day-old mixed-sex Cobb-500 broiler chicks were randomly allotted to four dietary treatments - Negative control (NC), NC + 0.05% bacitracin methylene disalicylate (BMD), NC + 0.3%ROD, and NC+0.5% ROD. Each treatment was assigned to eight replicates with six birds/replicate. On d 13 and 20, half of the birds were intraperitoneally injected with 1mL phosphate-buffered-saline /kg BW of birds (Unchallenged-group) and the remaining half with 1mg SE-LPS /kg BW of birds (Challenged-group). Average weight gain (AWG), average feed intake (AFI), feed conversion ratio (FCR), and mortality were determined weekly. On d 21, ten chickens/treatment were euthanized for measuring blood biochemical parameters, immune organ weights, caecal SCFA, and caeca microbiota. The SE-LPS decreased (P < 0.05) AWG and FCR on d 14 and 21, respectively. On d 14, 21, and overall basis, both ROD extract levels marginally improved (P < 0.05) the AWG of unchallenged birds compared to other treatments in the unchallenged-group. Challenged and unchallenged birds fed ROD extract had deeper (P < 0.05) crypt depth (CD) and higher villus height:CD, respectively, in the ileum. Globulin (GLB) and albumin:GLB were increased and reduced (P < 0.05), respectively, among birds fed 0.3%ROD compared to other treatments. There was no treatment effect on caeca SCFA, relative weight of immune organs, and serum antioxidants. Birds fed ROD extract had a higher (P < 0.05) relative abundance of caecal Lactobacillus and Streptococcus genera compared to the antibiotic treatment. Conclusively, incorporating 0.3% and 0.5%ROD extract into broiler chickens' nutrition improved growth performance and ileal morphology, and modified caecal microbiota of broiler chickens, regardless of the intraperitoneal SE-LPS challenge.


Asunto(s)
Pollos , Cornus , Alimentación Animal/análisis , Animales , Dieta/veterinaria , Suplementos Dietéticos , Lipopolisacáridos , Extractos Vegetales/farmacología , Salmonella enteritidis , Aumento de Peso
9.
Gerontol Geriatr Med ; 8: 23337214221097750, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35478850

RESUMEN

Objectives: To investigate the levels and interrelationships between fear of falling (FOF), physical activity (PA), social support (SS), and general self-efficacy (GSE) among older adults in a Nigerian community. Methods: This was a cross-sectional survey involving 100 older adults (65.0% females; mean age = 74.25 ± 8.01 years) consecutively recruited from Nnewi community. Participants' FOF, PA, GSE, and SS were assessed using standardized questionnaires. Data were analyzed using descriptive statistics, Spearman rank order correlation, and structural equation modeling at a 0.05 level of significance. Results: The participants' mean FOF, PA, GSE, and SS scores were 15.22 ± 7.43 (fearful), 114.76 ± 90.18 (low), 21.64 ± 8.25 (low) and 5.72 ± 1.19 (high) respectively. There were significant correlations between each pair of FOF, PA, GSE, and SS scores of the participants (p < .05). FOF and GSE were significant predictors of PA while GSE and SS were significant predictors of FOF. Conclusion: FOF and SS were high while PA and GSE were low in this sample of Nigerian older adults. Significant correlations existed between FOF, SS, GSE, and PA, with FOF and GSE being predictors of PA while GSE and SS significantly predicted FOF. Measures should be geared towards reducing FOF and improving PA, GSE, and SS in this group.

10.
Poult Sci ; 101(1): 101519, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-34794081

RESUMEN

The search for alternatives to antibiotics in poultry production is still on-going and has been directed towards investigation of the efficacy of different potential alternatives. However, it is important that the sought alternatives are cost-efficient and have no negative impact on meat quality, for ease of adoption and profit maximization. This study aimed at exploiting an agro-industrial waste, grape pomace (GP) as an alternative to in-feed antibiotics and assessing the effects on growth, intestinal morphology, ceca microbiota, ceca short-chain fatty acid (SCFA) concentration, blood biochemical parameters, and breast muscle myopathies of broiler chickens. A total of 576 one-day-old Cobb-500 broiler chicks were randomly allotted to 3 dietary treatments - Negative control (NC, a corn-wheat soybean-based diet), NC + 0.05% bacitracin methylene disalicylate (BMD), and NC + 2.5% GP. Each treatment was assigned to 8 replicate pens with 25 birds per pen. Body weight (BW), feed intake (FI), and feed conversion ratio (FCR) were determined weekly. On d 36, 2 chickens/pen were euthanized for measuring blood biochemical parameters, ceca SCFA, and ceca microbiota. White striping (WS) and wooden breast (WB) incidence were assessed in 4 chickens/pen on d 42. The GP diet increased (P < 0.05) average FI throughout the feeding phases compared to the other treatments, but overall FCR was similar. Birds in the GP treatment had higher (P < 0.05) villus height (VH) and increased VH:crypt depth ratio in the duodenum and jejunum compared to other treatments. The level of ceca SCFA and the incidence of WS and WB was the same for all treatments. Plasma Ca and P were significantly higher (P < 0.05) in birds fed GP and BMD, compared to the NC. Birds in the GP treatment had significantly reduced (P < 0.05) plasma aspartate transaminase than other treatments. Birds receiving GP had a higher (P < 0.05) relative abundance of the phylum Bacteroidetes and reduced (P < 0.05) Firmicutes compared to other treatments. The relative abundance of Bacteroides and Lactobacillus genera were higher (P < 0.05) among birds fed GP compared to other treatments. Inclusion of 2.5% GP in broiler chicken diets improved gut morphology and modified the cecal bacterial community and blood biochemical profiles with no adverse effect on growth performance and meat quality.


Asunto(s)
Enfermedades Musculares , Vitis , Animales , Pollos , Dieta/veterinaria , Músculos , Enfermedades Musculares/veterinaria
11.
Bioinform Biol Insights ; 15: 11779322211010703, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-35173424

RESUMEN

Breast cancer has consistently been a global challenge that is prevalent among women. There is a continuous increase in the high number of women mortality rates because of breast cancer and affecting nations at all modernization levels. Women with high-risk factors, including hereditary, obesity, and menopause, have the possibility of developing breast cancer growth. With the advent of radiotherapy, chemotherapy, hormone therapy, and surgery in breast cancer treatment, breast cancer survivors have increased. Also, the design and development of drugs targeting therapeutic enzymes effectively treat the tumour cells early. However, long-term use of anticancer drugs has been linked to severe side effects. This research aims to develop potential drug candidates from Moringa oleifera, which could serve as anticancer agents. In silico analysis using Schrödinger Molecular Drug Discovery Suite and SWISS ADME was employed to determine the therapeutic potential of phytochemicals from M oleifera against breast cancer via molecular docking, pharmacokinetic parameters, and drug-like properties. The result shows that rutin, vicenin-2, and quercetin-3-O-glucoside have the highest binding energy of -7.522, -6.808, and -6.635 kcal/mol, respectively, in the active site of BRCA-1. The essential amino acids involved in the protein-ligand interaction following active site analysis are ASN 1678, ASN 1774, GLY 1656, LEU 1657, GLN 1779, LYS 1702, SER 1655, PHE 1662, ARG 1699, GLU 1698, and VAL 1654. Thus, we propose that bioactive compounds from M oleifera may be potential novel drug candidates in the treatment of breast cancer.

12.
J Contemp Dent Pract ; 20(3): 370-376, 2019 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-31204331

RESUMEN

AIM: To determine and compare salivary fluoride retention after the use of different fluoride-containing chewing sticks and a non-herbal fluoridated toothpaste. MATERIALS AND METHODS: This double-blind cross-over experimental study was undertaken among twenty randomly selected senior secondary students in Ibadan, Nigeria. Saliva samples were collected to establish baseline fluoride concentration before the use of chewing sticks and non-herbal fluoridated toothpaste. Four commonly used chewing sticks and one non-herbal fluoridated toothpaste were each used at two days interval, and saliva samples were collected at 0, 10, 30, 45 and 60 minutes after each use. These samples were stored and transported in Gio'Style coolers to the laboratory, where they were analyzed for fluoride concentration using a spectrophotometer at a wavelength of 620 nm. Data were analyzed using descriptive and inferential statistics at p < 0.05. RESULT: At baseline mean (± SD) salivary fluoride concentration of participants was 25.95 (± 4.58) ppm. The mean (± SD) salivary fluoride concentration at 0 minutes was 228.0 (± 032.80) ppm, 427.65 (± 122.85) ppm, 413.45 (± 78.08) ppm, 329.05 (± 83.12) ppm and 323.80 (± 66.41) ppm corresponding to Alchornea laxiflora, Zanthoxylum zanthoxyloides, Anogeissus leocarpus, Masularia acuminate and non-herbal toothpaste respectively. At 60 minutes Zanthoxylum zanthoxyloides had the highest mean (± SD) fluoride concentration of 44.75 (± 13.32) ppm. The differences in mean (± SD) salivary fluoride concentrations amongst these tooth cleaning aids at 60 minutes were statistically significant (p < 0.001). CONCLUSION: Zanthoxylum zanthoxyloides had the highest mean (± SD) salivary fluoride retention followed by the non-herbal fluoridated toothpaste. CLINICAL SIGNIFICANCE: The use of chewing sticks can be a cost-effective and efficient means of caries prevention if used properly at regular interval.


Asunto(s)
Cariostáticos , Fluoruros , Pastas de Dientes , Método Doble Ciego , Humanos , Masticación , Nigeria
13.
Ann Ib Postgrad Med ; 16(2): 150-156, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-31217773

RESUMEN

BACKGROUND: Adopting good oral health practices such as regular tooth brushing and flossing; healthy nutritional habits and regular visits to the dentist, play a vital role in the wellbeing of an individual by preventing oral diseases such as dental caries and periodontal disease. Adequate knowledge of factors related to oral health may influence oral health practices leading to improved oral health. OBJECTIVE: The objective of this study was to assess the oral health knowledge and practice of a group of adults in Ibadan, Nigeria to enable planning of oral health services. METHODOS: A cross sectional survey involving 400 randomly selected traders at the Bola Ige Modern Market, Gbagi, Ibadan. A semi-structured interviewer-administered questionnaire was used to obtain information on socio-demographics, oral health knowledge and practice. Data was analyzed using descriptive statistics at p < 0. 05. RESULTS: The mean age of participants was 36.9 ±1.2, 37.0% had adequate knowledge that tooth decay was related to sweet food substances, but the majority (61.9%) consumed carbonated drinks at least once a week. Only 22.8% had ever visited a dentist in their life time and 5.8% in the last six months. Knowledge of who a dentist was associated with their level of education, with more participants who had tertiary education (83%) having greater knowledge (χ2= 38.3, p < 0. 001). About 70.3% of the study participants used a toothbrush and toothpaste to clean their teeth. CONCLUSION: There is poor oral health knowledge amongst adult Nigerians and they utilize oral health practices that do not engender good oral health.

14.
Niger J Clin Pract ; 20(5): 634-636, 2017 05.
Artículo en Inglés | MEDLINE | ID: mdl-28513526

RESUMEN

Carcinoid tumors are rare neuroendocrine tumors that have been reported in a wide range of organs but most commonly involve the gastrointestinal tract (stomach, ileum, appendix, and colon), and rarely ovary and thymus. We present a case of a 56-year-old Nigerian man with a cecal carcinoid tumor that was surgically removed. A 56-year-old Nigerian man, presented to our hospital with a year history of right-sided lower abdominal fullness, audible bowel sounds, occasional diarrhea, nausea, vomiting, and epigastric pain. There was no history of hematochezia or passage of melena stool. Colonoscopy revealed a cecal mass occupying more than two-thirds of the cecal lumen. Histology confirmed carcinoid tumor (well-differentiated neuroendocrine tumor), which was surgically removed. Carcinoid tumors are slow growing rare neuroendocrine tumors. Mortality is low if it is diagnosed early.


Asunto(s)
Tumor Carcinoide , Neoplasias del Ciego , Ciego/cirugía , Neoplasias Intestinales , Tumor Carcinoide/diagnóstico , Tumor Carcinoide/cirugía , Neoplasias del Ciego/diagnóstico , Neoplasias del Ciego/cirugía , Humanos , Neoplasias Intestinales/diagnóstico , Neoplasias Intestinales/cirugía , Masculino , Persona de Mediana Edad , Nigeria
15.
Artículo en Inglés | AIM (África) | ID: biblio-1262838

RESUMEN

Background: Postpartum depression is a problem of public health interest and impacts negatively on the perception of quality of lifer of sufferers. Quality of life' (QoL) as an outcome measure, is scantly used on women with postpartum depression in Nigeria. The current study was designed to assess the QoL of women with postpartum depression (PPD) in a tertiary hospital in North-Central, Nigeria.Method: A two-stage cross sectional procedure was used to recruit 550 participants 6 to 8 weeks postpartum in Jos, Northcentral, Nigeria. The Edinburgh Postnatal Depression Scale (EPDS), the World Health Organization Quality of Life-BREF-26 (WHOQoL-BREF-26) questionnaire and the Depression Module of the Structured Clinical Interview for DSM-IV axis I Diagnosis (SCID) were used.Results: The studied participants were 531 out which 21.8% with postpartum depression had significantly poor perception in all the four domains of the WHOQoL-BREF-26 i.e., in the physical health (p<0.001), psychological (p<0.001), social relationships (p<0.001) and environmental (p<0.001) domains. On the whole, the overall rating of quality of life (p=0.002) and satisfaction with general health (p<0.001) were also perceived to be poor when compared to those without depression. However, regression model analysis showed that the presence of postpartum depression in a participant predicts a significant negative perception on physical and environmental domains of quality of life, but a positive prediction on the general satisfaction with health. Conclusion: Postpartum depression as a disorder of public health importance impacts on the perception of quality of life of women who suffer from it. Early detection and treatment will improve the quality of life of women with postpartum depression


Asunto(s)
Depresión Posparto , Diagnóstico Precoz , Nigeria , Calidad de Vida , Mujeres
16.
Ann Ib Postgrad Med ; 14(1): 35-40, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-27721684

RESUMEN

BACKGROUND: Access to dental services improves oral health and thereby, overall general health. For people with limited or no access to oral health care services, outreach dental services may be used to reduce oral health inequality. There is however paucity of information on the economic analysis of outreach dental services in sub Saharan Africa. OBJECTIVE: To report a cost minimization analysis of an outreach dental service as compared with a primary oral health clinic. METHOD: A comparative analysis of the costs expended in the treatment of patients at an outreach dental service of the University College Hospital, Ibadan was done versus the costs that would have been incurred if the patients had been treated at a Primary Oral Health Clinic of the same institution. RESULTS: A total of three hundred and forty two (342) participants were attended to at the outreach dental service. More than 80% of the 123 participants examined had an unmet oral health need. The procedures carried out were in keeping with the basic package of oral care. The average cost of the outreach per participant was ₦530 (~$2.50) only versus an estimate of ₦868 (~$4.13) per participant if the programme had been clinic based. The total cost savings was ₦115,344 (~$549.26). CONCLUSION: Outreach dental services provide similar dental treatment to services in a primary oral health clinic at a reduced cost.

17.
Afr J Med Med Sci ; 45(2): 143-149, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-29465857

RESUMEN

BACKGROUND: There is sparse information about oral health seeking behaviour of children in rural areas of developing countries. The aim of the Study was to determine the dental care seeking-behaviour of children attending the first rural based community oral health centre in Nigeria. METHODS: A retrospective review of records of patients aged 16 years or younger treated at the Primary Oral Health Care Centre in Ibarapa, Nigeria over six years was conducted. Data on sociodemographic characteristics of the patients, pattern of presentation and their oral hygiene practices were collected and processed using SPSS. RESULTS: A total of 239 paediatric patients were seen during the period with a mean age of 9.7 ± 4.4 years and 132 (55.2%) were males. The majority, 225 (94.1%), were presenting for the first time. All the children sought dental care for one problem or the other and the most common reasons for seeking care were: tooth ache in 105 (43.9%), trauma in 30 (12.6%) and perceived unclean mouth in 20 (8.4%) patients. Older children were more likely to seek dental care because of pain (p < 0.00 1), while younger children sought care principally on account of trauma (p < 0.001) and the under 5 years were seen more often for gum ache (p =0.006). The majority, 175 (73.2%), used toothbrush and 182 (76.2%) cleaned their teeth once daily. CONCLUSION: None of the children presented for routine check-up, rather, consultation was as a result of dental problems with toothache being the most common reason.


Asunto(s)
Atención Odontológica , Higiene Bucal , Aceptación de la Atención de Salud , Adolescente , Niño , Preescolar , Femenino , Humanos , Masculino , Nigeria , Medicina Preventiva , Estudios Retrospectivos , Población Rural , Odontalgia
18.
Niger J Med ; 22(3): 212-7, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-24180150

RESUMEN

BACKGROUND: Although, the association between oral health care practices and sociodemographic characteristics of populations have been documented, information is sparse on sociodemographic indices influencing oral health practices of residents of traditional communities. The study aimed to describe the oral health practices of adult inhabitants of a traditional community in Nigeria. METHODS: A descriptive, cross-sectional study involving adult residents in randomly selected houses in Idikan, Ibadan, Nigeria. Data on their oral health care practices was obtained with the use of structured interviewer administered questionnaires. Data was analysed with SPSS and test of association carried out using Chi square. RESULTS: A total of 390 adult residents participated in the study, of which 56.2% were males. A total of 196 (50.3%) participants used toothbrush solely to clean their teeth, 72 (18.5%) used chewing sticks alone while 119 (30.5%) used both tooth brush and chewing stick. Older residents of the community, those with no formal education and in lower occupational classes were more likely to use chewing stick (p < 0.05). The majority (68.7%) cleaned their teeth once daily, 30% cleaned twice while 1.3% cleaned infrequently. Educational level attained and occupational class were significantly related to frequency of oral hygiene. Nearly all (95.4%) of the participants knew that oral health services are available in most hospitals, yet only 35.9% had ever visited a dental centre with a significantly higher proportion being males (p < 0.05). CONCLUSION: The study showed that the oral health practices of a typical traditional community in Nigeria are highly influenced by socioeconomic considerations.


Asunto(s)
Conductas Relacionadas con la Salud , Salud Bucal/estadística & datos numéricos , Higiene Bucal/estadística & datos numéricos , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Nigeria , Factores Socioeconómicos , Encuestas y Cuestionarios , Salud Urbana/estadística & datos numéricos
19.
Niger J Clin Pract ; 16(1): 5-11, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23377461

RESUMEN

BACKGROUND: The quality of healthcare has become a topical issue in recent years and the introduction of quality assurance that constitute some of the tools for change is now an important development in healthcare practice. OBJECTIVES: This study aims at evaluating the quality of care provided at the Paediatric Dental Clinic of the University College Hospital (UCH), Ibadan. MATERIALS AND METHODS: A descriptive study was conducted among 141 parents of children who attended the clinic over a 3-month period using a modified quality of care questionnaire by Ygge and Arnetz (2001). RESULTS: Majority of the parents (93.6%) were pleased with the registration process, while 81.6% and 66.7% were satisfied with the waiting arrangements and social amenities such as light and water respectively. Ratings of the quality of care indices revealed that 50.4% and 41.1% of the parents were happy with the information process and accessibility respectively. Over 80.0% of the respondents were pleased to a great degree with the dental treatment their children received. However, 44 (31.2%) said that they felt that they could not especially/not at all contact their dentist by telephone. About a fifth, (21.2%), felt they had not especially/not at all received information about how to prevent their child's dental problem. Inability of the dentists to introduce themselves was reported by 56.8% of the parents. The mean waiting time spent before being attended was 64.9 minutes while the desired average waiting time was 20.1 minutes. CONCLUSION: Parents were extremely satisfied with the dental treatment their children received at the UCH and had great confidence in staff competence even though they complained of long waiting time. However, there is a communication gap between the dentist, patients, and parents, since some of the dentists failed to introduce themselves and give information on prevention of dental diseases. For this reason, patients' appointments should be spread out to reduce waiting time. Furthermore, staff should introduce themselves and efforts must be made to improve health education given to parents. The dental curriculum should emphasize patient-dentist relationships.


Asunto(s)
Clínicas Odontológicas/normas , Pediatría , Garantía de la Calidad de Atención de Salud , Indicadores de Calidad de la Atención de Salud/normas , Adulto , Actitud del Personal de Salud , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Nigeria , Encuestas y Cuestionarios
20.
Ann Ib Postgrad Med ; 11(1): 18-21, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25161418

RESUMEN

BACKGROUND: School teachers play key roles in imparting appropriate and up-to-date knowledge to pupils and students. However, most teachers in developing countries like Nigeria have poor knowledge and motivation about oral health which may be due to inadequate training in the area of oral health. This might be one of the reasons for the poor oral hygiene among them and their students. OBJECTIVES: To evaluate the effectiveness of an oral health care training programme organized for teachers in Eruwa, Oyo state, Nigeria. METHODS: An intervention study was conducted among 40 school teachers who attended a two day oral health training workshop at Eruwa, headquarters of Ibarapa East Local Government Area. Training methods included lectures and demonstrations on aetiology, clinical features, treatment and prevention of common oral diseases. Pre- and post- evaluation written tests were administered to the participants to assess the effectiveness of the training. The knowledge scores were rated as poor, fair and good knowledge scoring <50.0%, 50.0-60.0% and > 60.0% respectively. Frequencies, percentages and means of relevant variables were generated. Paired t-test was used to compare means at P<0.05. RESULT: The mean age of the teachers was 40.13 ±7.24 years. There were 16 (40.0%) males and 24 (60.0%) females. Twenty (50.0%) of the participants had poor pre-training knowledge as compared to 7 (17.5%) after the training. Thirteen (32.5%) had fair pre-training knowledge as compared to 17 (42.5%) post training. Only (2.5%) of the participants had good pre-training knowledge as compared to 18 (45.0%) post training. The mean scores of the pre- and post-evaluation tests were 31.70 ±11.31 and 48.20 ±11.16 respectively. There was a statistically significant difference between the mean scores of the pre and post evaluations P<0.05. CONCLUSIONS: The training workshop improved the knowledge of school teachers regarding oral health.

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