RESUMEN
BACKGROUND: The cardinal signs and symptoms of adult-onset Still's disease (AOSD) include periodic fever, arthralgia and arthritis, lymphadenopathy, hepatosplenomegaly, an evanescent rash accompanied by neutrophilic granulocytosis, and a negative rheumatoid factor and antinuclear antibody test. OBJECTIVE: To alert clinicians and dermatologists to internal diseases such as AOSD when assisting patients with urticarial eruptions and systemic symptoms. METHODS: A case report of a 52-year-old white woman who received conventional therapy for urticaria for 3 years, with no improvement. Following this period, a diagnosis of AOSD was performed based on the presence of systemic symptoms. RESULTS: The inflammatory activity markers decreased by the second month of methotrexate therapy; however, the cutaneous lesions failed to disappear. Thalidomide was initiated, and total improvement of the cutaneous lesions was observed after 2 weeks. CONCLUSION: Urticarial rash is an uncommon presentation of AOSD, and clinicians must be alert to the possibility of a misdiagnosis in these cases.
Asunto(s)
Enfermedad de Still del Adulto/diagnóstico , Urticaria/diagnóstico , Diagnóstico Diferencial , Femenino , Humanos , Persona de Mediana Edad , Enfermedad de Still del Adulto/complicaciones , Urticaria/etiologíaRESUMEN
Relatamos um caso raro de paciente do sexo feminino, 32 anos com diagnóstico de Artrite Psoriásica que na evoluçäo apresentou Hiperprolactinemia e conseqüente galactorréia e amenorréia. Esta associaçäo mostrou um caso raro na literatura médica nos últimos dez anos