Asunto(s)

Bases de Datos Genéticas , Genética de Población , Repeticiones de Microsatélite/genética , Frecuencia de los Genes , Humanos , Eslovaquia

RESUMEN

The genotype polymorphism studies were carried out on two different populations: Eastern Slovak Caucasian (138) and Romany (Gypsy) (138), both from the town of Presov, at 15 highly polymorphic short tandem repeats (STRs) loci. The selected kit PowerPlex 16 system (Promega) included amelogenin, two penta-nucleotide repeats and 13 tetra-nucleotide repeats. The comparison of the allele frequencies between Eastern Slovak Caucasians and Romanies has shown significant differences in the majority of the focused loci. The P-values of exact test for Hardy-Weinberg equilibrium probabilities, observed and expected heterozygosity, matching probability, power of discrimination and exclusion, polymorphic information content, typical paternity index, genetic diversity and the other population-genetic indices were calculated.

Asunto(s)

Variación Genética , Repeticiones de Microsatélite/genética , Población Blanca/genética , Amelogenina/genética , ADN/genética , ADN/aislamiento & purificación , Etnicidad/genética , Tamización de Portadores Genéticos , Humanos , Pérdida de Heterocigocidad , Mucosa Bucal , Oligodesoxirribonucleótidos/química , Oligodesoxirribonucleótidos/genética , Reacción en Cadena de la Polimerasa , Polimorfismo Genético , Valores de Referencia , Eslovaquia