RESUMEN

It has been shown that inclusion of the specialized product containing 50% from recommended daily consumption of calcium, 20% of protein, 17-60% of 11 mineral substances and 11 vitamins in the diet of patients suffering from diseases of gastroenteric tract and osteopenia within 6 months lead to increasing of bone mineral density while it has not liquidated the existing vitamin B2 and vitamin D deficiency. The data obtained confirm the expediency of the development of specialized products of the set chemical composition intended for a concrete category of patients, and their inclusion in the diet.

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The data on of alimentary risk factors of osteoporosis have been observed. The frequency of decreased bone mineral density, vitamin and calcium diet content and sufficiency with vitamins evaluated by means of blood serum level determination among patients suffering from chronic diseases (of cardiovascular system, gastrointestinal tract, osteopenia and osteoporosis).

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RESUMEN

It has been shown that inclusion of the specialized product containing 50% from recommended daily consumption of calcium, 20%--of protein, 17-60%--of 11 mineral substances and 11 vitamins in the diet of patients suffering from diseases of gastroenteric tract and osteopenia within 6 months lead to increasing of bone mineral density while it has not liquidated the existing vitamin B2 and vitamin D deficiency. The data obtained confirm the expediency of the development of specialized products of the set chemical composition intended for a concrete category of patients, and their inclusion in the diet.

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With the purpose of a choice of optimal biochemical parameters for individual diagnostics of bone tissue mineralization disturbances bone mineral density (T-criterion), a blood serum level of the transport form of vitamin D (25-OH D), osteocalcin and calcitonin, and also calcium daily urine excretion and calcium excretion in morning urinary portion per creatinin has been determined. The most informative parameters have appeared T-criterion, blood serum level of 25-OH D3) or osteocalcin due their interchangeability, and also calcium urine excretion per creatinin.

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It has been shown that among patients suffering from adiposity and cardiovascular diseases and osteopenia deficiency of vitamins C, E and D, estimated on their blood serum level, and also raised daily urinary excretion of vitamin B2 take place more often, than among patients with the same pathologies, but without osteopenia. The data obtained confirm the important role of these vitamins in the maintenance of a normal bone function.

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It has been shown that among patients suffering from diseases of a gastroenteric tract and osteopenia the calcium insufficiency estimated on daily calcium urinary excretion and the lowered level of the transport form of vitamin D in blood serum take place more often, than among patients with the same pathologies, but without osteopenia. The most significant risk factors of bone mass decrease at the patients who have transferred operations on organs of digestion are insufficient supply with calcium and vitamin D and the body weight loss.

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Two groups of patients were studied. Group 1: patients with cardiovascular diseases. Group 2: patients with diseases of a gastro-intestinal path. Half of group has weight less than 56 kg. The study reported that distinct changes of bone tissue (mineral density as well as a high rate of bone tissue resorption) expose more often by patient 2 group than patient 1 group. In the both groups, patients were sufficiently supplied with vitamin D; however, in group 1 the concentration of 25-OH D3 was 1.9 fold lower and was close to the lower norm bound.

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The analysis of a diet of patients with cardiovascular atherosclerosis diseases, suffering from obesity, and with a pathology of a gastroenteric path has not revealed authentic differences on nutrient consumption between subgroups of patients with normal and lowered bone mineral density. It has been demonstrated that for patients with cardiovascular diseases values of an index of osteopathy risk, corresponding to the minimal risk, and for gastric patients--the values reflecting the maximal risk, are typical.

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RESUMEN

It has been shown that inclusion of the specialized product containing 50% from recommended daily consumption of calcium, 20% of protein, 17-60% of 11 mineral substances and 11 vitamins in the diet of patients with cardiovascular diseases, adiposity and osteopenia within 6 months has prevented seasonal deterioration of vitamin D sufficiency and age reduction of mineral bone density while it has not liquidated the existing vitamin B2 deficiency. The data obtained confirm the expediency of the development of specialized products of the set chemical composition intended for a concrete category of patients, and their inclusion in the diet.

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