RESUMEN
Carotid artery web (CaW) is a rare focal fibromuscular dysplasia, which is an underappreciated risk factor for transient ischemic attack. This case illustrates the dynamic evolution of secondary thrombus and plaque in CaW, and the importance of carotid doppler ultrasound in early detection and follow-up.
Asunto(s)
Displasia Fibromuscular , Ataque Isquémico Transitorio , Accidente Cerebrovascular , Humanos , Ataque Isquémico Transitorio/etiología , Ataque Isquémico Transitorio/complicaciones , Arterias Carótidas , Displasia Fibromuscular/complicaciones , Displasia Fibromuscular/diagnóstico por imagen , Accidente Cerebrovascular/complicacionesRESUMEN
OBJECTIVE: Our study aimed to confirm whether coagulation function of patients presenting with intracerebral hemorrhage (ICH) was associated with onset of cerebral microbleeds (CMBs). METHODS: A total of 174 patients with basal ganglia ICH were divided into CMBs and non-CMBs groups. Indicators of coagulation function and other clinical data that included fibrinogen (FBI), prothrombin time (PT), activated partial thromboplastin time (APTT), and the international normalized ratio (INR) were compared by univariate and multivariate analysis between the two groups. A receiver operating characteristic (ROC) curve was plotted to determine the predictive value of coagulation function indicators for CMBs. RESULTS: Univariate analysis showed that APTT levels was significantly higher in the CMBs group than the non-CMBs group (30.20 ± 5.18 vs. 27.95 ± 4.19; p = .004), while there was no significant difference between PT, INR, and FBI. The proportion of male patients in the CMBs group was significantly higher than the non-CMBs group (76.58% vs. 52.38%, p = .001). Multifactor logistic regression analysis demonstrated that APTT and male gender were independent risk factors for CMBs in patients with ICH (OR 1.100, 95% CI: 1.026-1.180, p = .008; OR 2.957, 95% CI: 1.500-5.826, p = .002; respectively). ROC curve analysis indicated that the area under the curve of APTT and male gender for CMBs in patients with ICH was 0.641 and 0.621, respectively (p = .002 and .008; respectively). CONCLUSION: APTT was an independent risk factor for CMBs in patients with ICH.