RESUMEN
The paper reports a rare clinical case of congenital hypoproconvertinemia in an elderly woman repeatedly admitted to the Cardiological Department for the management of coronary heart disease and arterial hypertension. The detection of low prothrombin index in a series of analysis requiredfurther hematological examination that revealed the history of postoperative and postnatal hemorrhage along with markedly reduced factor VII level. These results were interpreted as evidence of a rare congenital pathology, hypoproconvertinemia.
Asunto(s)
Deficiencia del Factor VII/congénito , Deficiencia del Factor VII/diagnóstico , Anciano de 80 o más Años , Femenino , HumanosAsunto(s)
Antiinflamatorios no Esteroideos/efectos adversos , Planificación en Salud , Servicios Preventivos de Salud/normas , Gastropatías/inducido químicamente , Hemorragia Gastrointestinal/inducido químicamente , Hemorragia Gastrointestinal/epidemiología , Infecciones por Helicobacter/epidemiología , HumanosRESUMEN
Effect of acute lethal blood loss on character and frequency of cardiac arrhythmias in postresuscitation period has been studied. Experiments were carried out on mongrel male rats resuscitated after 4- and 6-min clinical death caused by acute blood loss. Electric cardiac instability was found in early postresuscitation period. Pacemaker migration, paroxysmal ventricular tachycardia, blockades and extrasystole that lead to ventricular fibrillation were observed in 20 percent of cases. Supported by correlative analysis it has been established that the main arrhythmogenic factors are abundance of catecholamines, free fatty acids, dienic conjugates, lactate and inhibition of Ca dependent ATPase. Antiarrhythmogenic effects of antihypoxant gutimin, the beta-adrenoreceptor blocker inderal, antioxidant oxypiridin-6 were noticed after their separate administration before clinical death. The same effect of carnosine and phosphocreatine administered during resuscitation also was noticed.