RESUMEN
CASE REPORTS: Intravitreal triamcinolone is being increasingly employed for the treatment of macular diseases. We report two cases of intraocular pressure elevation and cataract formation after intravitreal triamcinolone therapy, and wonder if these complications are more likely when this agent is used in young patients. Intravitreal triamcinolone was injected into both eyes of the two young patients with chronic posterior and intermediate uveitis refractory to peribulbar and oral corticosteroid therapy. Chronic cystoid macular edema improved in both patients, however the intraocular pressure increased, requiring topical antihypertensive therapy, and this was followed by accelerated cataract formation. DISCUSSION: Young age and chronic inflammation could be associated with an intraocular pressure rise and subsequent cataract development after intravitreal triamcinolone.
Asunto(s)
Antiinflamatorios/efectos adversos , Catarata/inducido químicamente , Hipertensión Ocular/inducido químicamente , Triamcinolona/efectos adversos , Adolescente , Femenino , Humanos , Uveítis/tratamiento farmacológicoRESUMEN
Casos clínicos: El uso de triamcinolona intravítreaestá extendiéndose como tratamiento de enfermedadesmaculares. Los efectos secundarios puedenvariar en jóvenes. Presentamos dos casos de incrementode la presión intraocular (PIO) y desarrollode cataratas. Dos pacientes jóvenes con uveítis crónicasrefractarias a glucocorticoides perioculares yorales, recibieron inyecciones intravítreas de triamcinolona.El edema macular crónico mejoró en ambos pacientes.Se produjo un incremento de PIO, seguido de laaparición acelerada de cataratas.Discusión: La juventud y la inflamación crónicapodrían estar asociadas a incrementos de PIO y elconsecuente desarrollo de cataratas tras inyecciónintravítrea de triamcinolona
Case reports: Intravitreal triamcinolone is being ;;increasingly employed for the treatment of macular ;;diseases. We report two cases of intraocular pressure ;;elevation and cataract formation after intravitreal ;;triamcinolone therapy, and wonder if these complications ;;are more likely when this agent is used in ;;young patients. ;;Intravitreal triamcinolone was injected into both ;;eyes of the two young patients with chronic posterior ;;and intermediate uveitis refractory to peribulbar ;;and oral corticosteroid therapy. Chronic cystoid ;;macular edema improved in both patients, however ;;the intraocular pressure increased, requiring topical ;;antihypertensive therapy, and this was followed by ;;accelerated cataract formation. ;;Discussion: Young age and chronic inflammation ;;could be associated with an intraocular pressure rise ;;and subsequent cataract development after intravitreal ;;triamcinolone
Asunto(s)
Femenino , Adolescente , Humanos , Antiinflamatorios/efectos adversos , Catarata/inducido químicamente , Hipertensión Ocular/inducido químicamente , Triamcinolona/efectos adversos , Uveítis/tratamiento farmacológicoRESUMEN
PURPOSE: To report the development of a cavitary choroidal melanoma in a patient with nevus of Ota and describe its magnetic resonance imaging (MRI) features. PATIENT: A 66-year-old man with right oculodermal melanocytosis and an ipsilateral choroidal cavitary melanoma was seen. Diagnosis was suspected on the clinical, ultrasonographic and MRI findings. RESULTS: T1-weighted image showed a hyperintense solid mass containing hypointense cystic-like spaces delineated by hyperintense septa with respect to the vitreous. The reverse image was observed on T2-weighted images. A choroidal melanoma comprising epithelioid and spindle cells with multilocular cavities was documented histopathologically. CONCLUSIONS: There may be an association between cavitary melanoma and nevus of Ota. Characteristic MRI findings could be helpful in the differential diagnosis of cavitary uveal melanoma.