1.
Angew Chem Int Ed Engl
; 56(46): 14694-14697, 2017 11 13.
Artículo
en Inglés
| MEDLINE
| ID: mdl-28952184
RESUMEN
This investigation demonstrates that a series of biphenylenes can be easily prepared from their corresponding halobiphenyls by the cyclization of inâ situ generated 2',3'-didehydro-2-lithiobiphenyls at low temperature. Two remarkable advantages of this synthetic method include 1)â the lack of any need for transition-metal catalysts or reagents in the cyclization, and 2)â the ability to obtain C1-functionalized products by treating the reaction intermediate 1-lithiobiphenylene with an electrophilic reagent. π-Extended derivatives, such as benzobiphenylenes, dibenzobiphenylene, linear/angular [3]phenylenes, and biphenyleno[2,3-b]biphenylenes, were synthesized similarly using suitable biaryls or teraryls.