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1.
Br J Cancer ; 101 Suppl 2: S13-7, 2009 Dec 03.
Artículo en Inglés | MEDLINE | ID: mdl-19956157

RESUMEN

OBJECTIVE: We aimed to develop and validate a measurement tool to assess cancer awareness in the general population: the cancer awareness measure (CAM). METHODS: Items assessing awareness of cancer warning signs, risk factors, incidence, screening programmes and attitudes towards help seeking were extracted from the literature or generated by expert groups. To determine reliability, the CAM was administered to a university participant panel (n=148), with a sub-sample (n=94) completing it again 2 weeks later. To establish construct validity, CAM scores of cancer experts (n=12) were compared with those of non-medical academics (n=21). Finally, university students (n=49) were randomly assigned to read either a cancer information leaflet or a leaflet with control information before completing the measure, to ensure the CAM was sensitive to change. RESULTS: Cognitive interviewing indicated that the CAM was being interpreted as intended. Internal reliability (Cronbach's alpha=0.77) and test-retest reliability (r=0.81) were high. Scores for cancer experts were significantly higher than those for non-medical academics (t(31)=6.8, P<0.001). CAM scores were higher among students who received an intervention leaflet than the control leaflet (t(47)=4.8, P<0.001). CONCLUSIONS: These studies show the psychometric properties of the CAM and support its validity as a measure of cancer awareness in the general population.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Neoplasias/diagnóstico , Adolescente , Adulto , Anciano , Femenino , Educación en Salud , Humanos , Masculino , Persona de Mediana Edad , Neoplasias/psicología , Psicometría , Reproducibilidad de los Resultados
2.
Br J Cancer ; 101 Suppl 2: S18-23, 2009 Dec 03.
Artículo en Inglés | MEDLINE | ID: mdl-19956158

RESUMEN

OBJECTIVE: To assess public awareness of cancer warning signs, anticipated delay and perceived barriers to seeking medical advice in the British population. METHODS: We carried out a population-based survey using face-to-face, computer-assisted interviews to administer the cancer awareness measure (CAM), a newly developed, validated measure of cancer awareness. The sample included 2216 adults (970 males and 1246 females) recruited as part of the Office for National Statistics Opinions Survey using stratified probability sampling. RESULTS: Awareness of cancer warning signs was low when open-ended (recall) questions were used and higher with closed (recognition) questions; but on either measure, awareness was lower in those who were male, younger, and from lower socio-economic status (SES) groups or ethnic minorities. The most commonly endorsed barriers to help seeking were difficulty making an appointment, worry about wasting the doctor's time and worry about what would be found. Emotional barriers were more prominent in lower SES groups and practical barriers (e.g. too busy) more prominent in higher SES groups. Anticipated delay was lower in ethnic minority and lower SES groups. In multivariate analysis, higher symptom awareness was associated with lower anticipated delay, and more barriers with greater anticipated delay. CONCLUSIONS: A combination of public education about symptoms and empowerment to seek medical advice, as well as support at primary care level, could enhance early presentation and improve cancer outcomes.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Neoplasias/diagnóstico , Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reino Unido
3.
Br J Cancer ; 101 Suppl 2: S24-30, 2009 Dec 03.
Artículo en Inglés | MEDLINE | ID: mdl-19956159

RESUMEN

OBJECTIVE: Little is known about ethnic differences in awareness of cancer-warning signs or help-seeking behaviour in Britain. As part of the National Awareness and Early Diagnosis Initiative (NAEDI), this study aimed to explore these factors as possible contributors to delay in cancer diagnosis. METHODS: We used quota sampling to recruit 1500 men and women from the six largest minority ethnic groups in England (Indian, Pakistani, Bangladeshi, Caribbean, African and Chinese). In face-to-face interviews, participants completed the newly developed cancer awareness measure (CAM), which includes questions about warning signs for cancer, speed of consultation for possible cancer symptoms and barriers to help seeking. RESULTS: Awareness of warning signs was low across all ethnic groups, especially using the open-ended (recall) question format, with lowest awareness in the African group. Women identified more emotional barriers and men more practical barriers to help seeking, with considerable ethnic variation. Anticipated delay in help seeking was higher in individuals who identified fewer warning signs and more barriers. CONCLUSIONS: The study suggests the need for culturally sensitive, community-based interventions to raise awareness and encourage early presentation.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Grupos Minoritarios/psicología , Neoplasias/diagnóstico , Neoplasias/etnología , Aceptación de la Atención de Salud , Adolescente , Adulto , Anciano , Diagnóstico Tardío , Inglaterra , Femenino , Humanos , Lenguaje , Masculino , Persona de Mediana Edad , Neoplasias/psicología
4.
Nucleic Acids Res ; 20(17): 4599-606, 1992 Sep 11.
Artículo en Inglés | MEDLINE | ID: mdl-1408762

RESUMEN

We describe here the integration of image analysis and robotics to produce a fully automated colony picking/plate handling system. Biological tests were performed to verify its performance in terms of sterilisation and accuracy of picking. The machine was then used by a single operative to pick a 36,000 clone cDNA library in approximately 42 hrs over 5 days.


Asunto(s)
Automatización/instrumentación , Recuento de Colonia Microbiana/instrumentación , Bacteriófago lambda/genética , Clonación Molecular , Escherichia coli/genética , Biblioteca de Genes , Procesamiento de Imagen Asistido por Computador/instrumentación , Reacción en Cadena de la Polimerasa , Robótica/instrumentación
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