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Org Chem Front ; 7(7): 913-918, 2020 Apr 07.
Artículo en Inglés | MEDLINE | ID: mdl-32368346

RESUMEN

A metal-free aromative cascade has been developed for the synthesis of diverse heterocycles from readily accessible hydroxy/aminochalcones and acid/alkyl halides. The cascade being by a base-mediated intramolecular aldol cyclization/dehydration sequence to provide a triene, which sets the stage for a 6π-electrocyclization/oxidative aromatization to access diverse heterocyclic scaffolds.

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