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BACKGROUND: Disposable mechanical negative pressure wound therapy (dNPWT) can help manage lower extremity wounds in the outpatient clinic. PURPOSE: We assessed dNPWT use in 16 patients at a podiatry clinic. METHODS: Patients were treated between October 31, 2019 and December 16, 2021. All patients received dNPWT with dressing changes every 2 to 3 days. Demographics, baseline wound and subsequent wound visit data, and treatments were recorded. Wound healing outcomes were assessed. RESULTS: Average patient age was 59.6 ± 8.9 years old. Patient comorbidities included poor nutritional status, diabetes, and hypertension. Wound types consisted of 6 diabetic foot ulcers, 9 surgical wounds, and 1 pressure injury. At baseline, the average wound age was 15.6 weeks, average area was 5.5 cm2, and average volume was 3.3 cm3. The average time from presentation to end of dNPWT was 45.5 days. In this timeframe, wounds improved in granulation tissue amount (81%), reduced in area (63%), and reduced in volume (69%). By the end of treatment, a majority of patients (88%) displayed 76% to 100% wound bed coverage with healthy granulation tissue. The remaining 12% showed <76% coverage with granulation tissue. CONCLUSIONS: In this retrospective study, 14 of 16 patients displayed improvement in wound area, volume, and granulation tissue amount during dNPWT treatment.

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Sigmoid sinus diverticula are relatively rare but typically cause pulsatile tinnitus (PT) in the involved ear. Occasionally, symptoms produced by blood flowing through the diverticulum are severe enough to necessitate recontouring the sigmoid sinus. Recently, a 59-year-old female was evaluated after years of worsening unilateral PT. CT angiography identified a 5 mm sigmoid sinus diverticulum near the sinodural angle. Given the severity of symptoms, the patient's diverticulum was surgically decompressed and recontoured using hydroxyapatite bone cement.

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BACKGROUND: Several different techniques are used for wound closure. Cyanoacrylate tissue adhesives are less invasive and easy to apply, and the cosmetic results are comparable to or better than the conventional methods for wound repair. The purpose of this study is to demonstrate that Dermabond Topical Skin Adhesive, 2-octylcyanoacrylate (a registered trademark of Ethicon) is an effective barrier against the penetration of microorganisms in an in vitro model. MATERIALS AND METHODS: Octylcyanoacrylate adhesive was evaluated in vitro as a barrier to microbial penetration using a strike through test. Agar media containing pH sensitive dye was used. The dye changed color in the presence of acidic microbial metabolic products. Octylcyanoacrylate adhesive was applied to the agar surface to form uniformly thick films. A total of 300 single layered films and an additional 300 triple layered films were evaluated. A 10-microL aliquot of inoculum containing at least 1x10(3) cfu was applied to the surface of each film. Plates were incubated at 37 degrees C for 72 h and were observed for growth and color change every 24 h during the incubation period. RESULTS: A series of binomial calculations were performed, varying the level of effectiveness of the test and the level of statistical confidence. Of the 600 test articles evaluated, 598 retained their patency at the end of 72 h. One individual test film was invalidated due to extrinsic contamination. The data presented indicated that octylcyanoacrylate tissue adhesive provided a barrier to microbial penetration with 95% confidence of 99% efficacy for 72 h in this in vitro model. CONCLUSION: The results of these in vitro experiments supported the hypothesis that octylcyanoacrylate tissue adhesive is an effective barrier to microbial penetration by gram-positive and gram-negative motile and nonmotile species.

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