RESUMEN
The purpose of this paper was to present 2 cases of green pigmentation in primary teeth caused by hyperbilirubinemia, from different pathologies during the neonatal period. Medical history revealed systemic problems during the neonatal period of an infectious, neurological, renal, respiratory, and cardiological nature, as well as a high amount of bilirubin in both cases and hepatitis in the first. The staining in the teeth was due to hyperbilirubinemia, caused by these systemic conditions. The clinical characteristics of teeth may help in the diagnosis of present current or past systemic diseases. The reported cases confirm the relevance of past medical history in establishing the diagnosis of the etiology of green pigmentation as a result of high levels of bilirubin serum.