Asunto(s)
Ambiente , Enfermedades de la Piel/epidemiología , Adolescente , Adulto , California , Femenino , Humanos , Humedad , Masculino , Persona de Mediana Edad , Medicina Militar , Texas , VietnamRESUMEN
A 21-year-old woman developed huge atrophic striae in the axillary and inguinal areas from the topical application, with occlusion, of potent corticosteroid preparation applied to the axillary or inguinal areas. It is postulated that the mechanism is systemic absorption of enough medication to produce a state of hyperadrenalism with subsequent striae formation as a sequela.
Asunto(s)
Corticoesteroides/efectos adversos , Enfermedades de la Piel/inducido químicamente , Administración Tópica , Corticoesteroides/administración & dosificación , Corticoesteroides/metabolismo , Adulto , Axila , Femenino , Humanos , Muslo , Triamcinolona Acetonida/administración & dosificación , Triamcinolona Acetonida/efectos adversos , Triamcinolona Acetonida/metabolismoRESUMEN
Delayed hypersensitivity (DH) to seven common antigens was examined in 38 men with chronic dermatophyte infections and in 20 controls. A similar percentage of the infected and the control groups reacted to four antigens. In addition to showing a low frequency of DH to trichophytin, the infected group also showed a significant reduction in their reactions to intradermal mumps skin test antigen and to a Rhus oleoresin patch test. Two members (5%) of the infected group were anergic to all tests. Patients with chronic dermatophytosis appear to have a relatively specific defect in DH to trichophytin, but their cell-mediated responses to other antigens may also be somewhat decreased. The subjects studied did not appear to suffer excessive morbidity from infectious diseases, other than dermatophytosis.