RESUMEN
BACKGROUND: According to a previous study, a longer insertion time was associated with inadequate bowel cleansing, advanced age, constipation, surgical history, sex, and a low body mass index. However, there are only a few studies on the association between cecal insertion time and colonoscope length (long vs intermediate). OBJECTIVE: To assess the association of colonoscope length and cecal insertion time. DESIGN: Prospective comparative trial, with systematic assignment to colonoscope length. PATIENTS: A total of 998 colonoscopic examinations were performed by a single endoscopist, who used video colonoscopes. MAIN OUTCOME MEASUREMENTS: Cecal insertion times and their potential covariates. RESULTS: The mean (+/-SEM) age was 49.06 +/- 0.4 years, 61% were men, and the mean (+/-SEM) body mass index was 24.17 +/- 2.96. The mean (+/-SEM) cecal insertion time was 4.68 +/- 0.09 minutes. Multivariate regression analysis demonstrated that sex (female, P = .000), colonoscope length (long, P = .000), increasing age (P = .000), percentage of body fat (P = .006), and inadequate bowel cleansing (P = .002) were independent factors associated with a longer insertion time. LIMITATIONS: All procedures were performed by only one gastroenterologist, so the individual characteristics of colonoscopic procedures could be affected by a consequent bias. CONCLUSIONS: This large, cross-sectional study identified colonoscope length as a useful factor that affected cecal insertion time.
Asunto(s)
Ciego , Colonoscopios , Colonoscopía/métodos , Diseño de Equipo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de TiempoRESUMEN
BACKGROUND AND OBJECTIVES: To date, many studies have reported on the association of obesity with gastroesophageal reflux disease (GERD), although none of these have been systematic. In light of this, we conducted this study to examine the association of obesity and GERD. SUBJECTS AND METHODS: A total of 3363 patients underwent gastroscopy at Hanyang University Health Promotion Center. Among these patients, we prospectively examined patients who were diagnosed with GERD-related erosive esophagitis on endoscopy. RESULTS: Multivariate analysis showed that the significant risk factors were waist-to-hip ratio (WHR), hiatal hernia, body mass index (BMI), and smoking. As compared with patients who had a WHR less than 0.8, the multivariate odds ratio for erosive esophagitis were 4.055 for a WHR more than 1.0 and 2.316 for a WHR of 0.8 to 1.0. As compared with patients who had a BMI of 20 to 22.5, the multivariate odds ratio for erosive esophagitis was 3.308 (95% confidence interval, 1.792 to 6.107) for a BMI greater than 30. CONCLUSIONS: Obesity, especially abdominal obesity, was the significant risk factor for erosive esophagitis.
Asunto(s)
Grasa Abdominal , Esofagitis/epidemiología , Reflujo Gastroesofágico/epidemiología , Obesidad/epidemiología , Adulto , Composición Corporal , Índice de Masa Corporal , Estudios de Casos y Controles , Femenino , Reflujo Gastroesofágico/fisiopatología , Gastroscopía , Hernia Hiatal/complicaciones , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Oportunidad Relativa , Estudios Prospectivos , Factores de Riesgo , Fumar/efectos adversos , Relación Cintura-Cadera/efectos adversosRESUMEN
BACKGROUND/AIMS: Abdominal obesity and hyperinsulinemia or insulin resistance are of interest in connection with colon carcinogenesis. We conducted a prospective case controlled study for the evaluation of relationship between abdominal obesity, insulin resistance, and colorectal adenoma. METHODS: Fifty patients with colorectal adenoma and fifty healthy subjects were included in this study. Total colonoscopic examinations were performed in all the subjects. Fasting blood sugar (FBS), insulin, homeostasis model assessment (HOMA-IR), triglyceride (TG), cholesterol (CROL), BMI (body mass index), WHR (waist hip ratio), percent body fat (PBF) and obesity degree (OD) were measured. HOMA-IR was considered to represent insulin resistance. Diabetic patients were excluded from this study. RESULTS: There were no differences in sex, serum insulin, FBS, HOMA-IR, TG, CROL between adenoma and control group. Subjects with high BMI, WHR, percent body fat, and obesity were more likely to have colonic adenoma. Multiple logistic regression analysis after adjusting confounding factors, had revealed that WHR was the most important independent risk factor for colon adenoma. CONCLUSIONS: Abdominal obesity was most closely related to colonic adenoma. However, insulin resistance was not related to colonic adenoma. A larger case controlled study is needed.