RESUMEN
PURPOSE: To compare patient demographics, treatment resources, practice patterns, and outcome results for squamous cell carcinoma of the uterine cervix (SCC) between the 1978 and 1983 Patterns of Care studies (PCS) in the United States of America (USA) and a nonacademic center within a developing country. METHOD AND MATERIALS: Patient details (race, age, stage, and number per year), treatment used, and treatment outcome were retrieved from the charts of the 1160 cases registered at this center with SCC of the cervix between 1976 and 1985. Demographic variables and Kaplan-Meier survival estimates were calculated and compared with results from published PCS reviews. RESULTS: There is a significant difference in the racial group presentation of cervix cancer at this center compared with the PCS reviews (p < 0.005), and median ages are significantly lower at this center (t = p < 0.001). The proportion of patients with Stage III or more was significantly higher at this center than the PCS centers (24 vs. 47%, p < 0.001). There were also vast differences in facility resources. Fewer cases at this center underwent intracavitary insertions than at PCS centers. Mean Point A doses were significantly reduced for this center compared with the PCS reviews. Kaplan-Meier estimates were similar for Stage I and II in PCS centers and this center, but were inferior for this center in Stage III patients (p < 0.05 for OS and p < 0.01 for LC). Late morbidity rates were similar for both PCS centers and this center. CONCLUSION: PCS recommendations may be applicable to nonacademic centers within developing countries, if the latter use staging techniques that are consistent with the PCS staging guidelines.
Asunto(s)
Carcinoma de Células Escamosas/radioterapia , Neoplasias del Cuello Uterino/radioterapia , Braquiterapia , Carcinoma de Células Escamosas/etnología , Carcinoma de Células Escamosas/patología , Femenino , Estudios de Seguimiento , Humanos , Estadificación de Neoplasias , Pautas de la Práctica en Medicina , Dosificación Radioterapéutica , Factores Socioeconómicos , Sudáfrica , Resultado del Tratamiento , Estados Unidos , Neoplasias del Cuello Uterino/etnología , Neoplasias del Cuello Uterino/patologíaRESUMEN
Seventeen patients who presented with stage i squamous carcinoma of the cervix between 1969 and 1974 are reviewed. Thirteen of the patients were treated by means of radical irradiation, 3 by Wertheim's hysterectomy and 1 by a simple hysterectomy and postoperative pelvic irradiation. Two patients died 2 years after presentation, 1 from metastases and 1 from unrelated causes. The remaining 15 patients were well with no evidence of malignancy 5 years after presentation.