Asunto(s)
Programas Controlados de Atención en Salud/tendencias , Servicio de Patología en Hospital/tendencias , Patología Clínica/tendencias , Ahorro de Costo , Costos de la Atención en Salud/tendencias , Programas Controlados de Atención en Salud/economía , Programas Controlados de Atención en Salud/organización & administración , Patología Clínica/economía , Patología Clínica/organización & administración , Sociedades Médicas , Estados UnidosRESUMEN
A patient with gastric ulceration and hemorrhage due to multiple antral gastric submucosal lipomas is presented. The number and close apposition of the lipomas resulted in loss of the usual gastroscopic and radiologic findings associated with these benign tumors. Complications arising from both singly occurring and multiple gastric lipomas are discussed.
Asunto(s)
Lipomatosis/diagnóstico , Neoplasias Primarias Múltiples/diagnóstico , Neoplasias Gástricas/diagnóstico , Gastrectomía , Hemorragia Gastrointestinal/etiología , Gastroscopía , Humanos , Lipomatosis/patología , Masculino , Persona de Mediana Edad , Neoplasias Primarias Múltiples/patología , Neoplasias Gástricas/patologíaRESUMEN
The advent of the radioimmunoassay of Beta subunit chorionic gonadotropin (BhCG) has eliminated a major problem in following the patient with gestational trophoblastic neoplasia (GTN). Whole hCG cross reacts with luteinizing hormone (hLH) causing difficulties when GTN patient titers fall to levels coincidental with pituitary levels of hLH. The use of the Beta subunit of hCG in radioimmunoassay has eliminated this problem because there is essentially no cross reaction between the B-subunit of the hCG and hLH. A review of the use of this sensitive assay in the management of patients with GTN is presented.
Asunto(s)
Gonadotropina Coriónica/sangre , Neoplasias Trofoblásticas/diagnóstico , Gonadotropina Coriónica/inmunología , Reacciones Cruzadas , Femenino , Humanos , Hormona Luteinizante/inmunología , Sustancias Macromoleculares , Embarazo , Radioinmunoensayo , Neoplasias Trofoblásticas/sangreRESUMEN
The persistent infection of embryonic chicken tracheal organ cultures with Newcastle disease virus (NDV) is described. Tracheal explants remained morphologically intact and were able to support the replication of NDV for 6 months. Peak titers of released virus occurred at 1 week postinfection, whereas maximal immunofluorescence was not observed until 30 days postinfection. The inoculum titer was not critical, and viral persistence resulted with either of two strains of NDV tested. Serum was not required in the medium for explant viability or to maintain the persistent infection. The presence of a contaminating virus morphologically resembling a leukovirus neither altered the course of infection nor affected the survivability of explants. Although interferon was not detected in the culture medium, persistently infected explants were resistant to heterologous viral challenge, and a similar resistant state could be induced in uninfected explants with exogenous interferon or ultraviolet light-inactivated NDV. No evidence was found to implicate antibody as a regulatory factor in the establishment or maintenance of persistence. The results from electron microscopy and immunofluorescence suggest the cells of the subepithelial connective tissue as the site of NDV persistence.
Asunto(s)
Enfermedad de Newcastle/inmunología , Virus de la Enfermedad de Newcastle/inmunología , Tráquea/inmunología , Animales , Embrión de Pollo , Pollos/inmunología , Cilios/inmunología , Medios de Cultivo , Técnicas de Cultivo , Técnica del Anticuerpo Fluorescente , Caballos/inmunología , Sueros Inmunes , Inmunodifusión , Interferones/biosíntesis , Microscopía Electrónica , Poli I-C , Rayos Ultravioleta , Virus de la Estomatitis Vesicular Indiana/inmunología , Ensayo de Placa ViralAsunto(s)
Carcinoma de Células Escamosas/patología , Regresión Neoplásica Espontánea , Neoplasias de la Vulva/patología , Adolescente , Carcinoma de Células Escamosas/microbiología , Pruebas de Fijación del Complemento , Femenino , Humanos , Microscopía Electrónica , Embarazo , Simplexvirus/inmunología , Simplexvirus/aislamiento & purificación , Neoplasias de la Vulva/microbiologíaAsunto(s)
Adenocarcinoma/microbiología , Herpesviridae/crecimiento & desarrollo , Neoplasias Renales/microbiología , Rana pipiens , Temperatura , Adenocarcinoma/veterinaria , Animales , Cámara Anterior , Técnicas de Cultivo , Neoplasias Renales/veterinaria , Microscopía Electrónica , Trasplante de Neoplasias , Estaciones del Año , Replicación ViralRESUMEN
A herpes-type virus was induced in explants of "summer-phase" Lucké tumor maintained on agar slants at 7.5 C for 13 to 14 weeks.