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BACKGROUND: The COVID-19 pandemic had major impacts on the physical lives of individuals, especially on home office workers. In this way, the practice of physical activity has been identified as an ally in the reduction and prevention of musculoskeletal pain. OBJECTIVE: To investigate the association between leisure-time physical activity and musculoskeletal pain in adult workers before and during the COVID-19 pandemic. METHODS: A cross-sectional study was conducted with 374 workers of both sexes (age = 46.5±10.5 years). Leisure-time physical activity, number of pain sites, and musculoskeletal pain status were investigated using a questionnaire designed for the study. Statistical analysis was performed using Multinomial Logistic Regression. The significance level adopted was 5%. RESULTS: A significant association was found between physical activity status and the number of pain sites (p = 0.002). In addition, an inverse association was found between physical activity before and during the quarantine and the number of pain sites (two pain sites - OR = 0.40; 95% CI = 0.2-0.7; three or more pain sites - OR = 0.24; 95% CI = 0.1-0.5). Physical activity interruption during quarantine increased pain perception by 2.86 times (OR = 2.86; 95% CI = 1.0-7.5). CONCLUSIONS: The findings showed that physical activity before and during the pandemic was a protective factor for body pain during the COVID-19 pandemic.

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Trypanosoma cruzi, a flagellated protozoan, is the causative agent of Chagas disease. The parasite has developed various mechanisms to get through its intricate life cycle and adapt to different evolutionary phases. T. cruzi proliferates in the insect vector's digestive tract as an epimastigote form, encountering fluctuating nutrient availability and oxidative stress caused by the digestion of red blood cells from the mammalian host blood meal. To unravel how the parasite's metabolism adapts to these changing conditions, we conducted an analysis of the chemical species present in epimastigote forms. This involved comparing cultured parasites with those subjected to nutritional deficiency or oxidative stress using untargeted metabolomics. We looked at 21 samples: seven biological copies of parasites that were actively growing, seven samples that were put in a medium without nutrients for 3 h, and seven samples that were treated with glucose oxidase for 30 min to make H2O2 continuously. Importantly, in all conditions, parasite viability was maintained when the samples were collected. Upon nutrient removal, we observed a substantial decrease in amino acids and carbohydrate metabolites, accompanied by the accumulation of fatty acids and steroids, with the predominance of inositol and sphingolipid metabolism, along with a simultaneous decrease in the levels of H2O2. In the presence of H2O2, a significant rise in components of the pentose pathway and specific amino acids such as methionine and serine occurred, along with pathways related to an increase in antioxidant species metabolism such as ribulose 5-phosphate and glyceric acid. Conversely, fatty acid and steroid levels decrease. We found no common increase in metabolites or lipids. In contrast, eight species (succinic acid, glutamic acid, valine, 2-hydroxyisocaproic acid, alanine, indolelactic acid, proline, and lanosterol) were consumed under both stresses. These findings underscore the rapid and distinct enrichment responses in amino acids, lipids, and carbohydrates required to cope with each different environmental condition. We concluded that T. cruzi presents a flexible metabolism that rapidly adapts to variable changes in the environment.

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The objective of this study was to compare the indirect methods of obtaining digestibility with the direct method of total fecal collection to estimate the apparent digestibility of nutrients in sheep and goats supplemented with non-protein nitrogen. Five goats and five sheep with no defined racial pattern were used, distributed in two 5 × 5 Latin squares, with split plots, considering the diets as plots and the apparent digestibility determination methodologies as subplots. The diets were composed of buffelgrass hay and the addition, via ruminal infusion, of increasing amounts of nitrogen supplementation in order to gradually raise the CP level of the basal diet in intervals of 2% points, that is, + 2, +4, + 6 and + 8%. Samples of the feeds offered, and the leftovers were collected daily during the five days of collection to determine the nutrient intake, as well as the total collection of feces to determine the apparent digestibility of the nutrients. The amount of fecal dry matter excreted was estimated by the concentration of Indigestible Acid Detergent Fiber (ADFi), Indigestible Neutral Detergent Fiber (NDFi), Indigestible Dry Matter at 244 h (DMi 244 h) and Indigestible Dry Matter at 264 h (DMi 264 h). Among the evaluated markers, DMi 264 h had the lowest accuracy in estimating fecal excretion and nutrient digestibility. For the goat species, the markers ADFi and DMi 244 h proved to be able to adequately predict fecal excretion and digestibility indices, while NDFi stood out for both species. Among the evaluated markers, NDFi is the one that most accurately estimates the nutrient digestibility of the diet for goats and sheep.

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OBJECTIVE: In this study, we aimed to investigate the effects of the concurrent exercise training (CET) associated with the enalapril maleate on blood pressure variability (BPV) and renal profile in an experimental model of arterial hypertension (AH) and postmenopause. METHODS: Female ovariectomized spontaneously hypertensive rats (SHR) were distributed into 4 groups (n = 8/group): sedentary (SO), sedentary + enalapril (SOE), trained (TO) and trained + enalapril (TOE). Both enalapril (3mg/kg) and CET (3 days/week) were conducted during 8 weeks. Blood pressure (BP) was directly recorded for BPV analyses. Renal function, morphology, inflammation and oxidative stress were assessed. RESULTS: The SOE, TO e TOE groups presented decreased systolic BP compared with SO. Both trained groups (TO and TOE) presented lower BPV and increased baroreflex sensitivity (TO: 0.76 ± 0.20 and TOE: 1.02 ± 0.40 vs. SO: 0.40 ± 0.07 ms/mmHg) compared with SO group, with additional improvements in TOE group. Creatinine and IL-6 levels were reduced in SOE, TO and TOE compared with SO group, while IL-10 was increased only in TOE group (vs. SO). Enalapril combined with CET promote reduction in lipoperoxidation (TOE: 1.37 ± 0.26 vs. SO: 2.08 ± 0.48 and SOE: 1.84 ± 0.35 µmol/mg protein) and hydrogen peroxide (TOE: 1.89 ± 0.40 vs. SO: 3.70 ± 0.19 and SOE: 2.73 ± 0.70 µM), as well as increase in catalase activity (vs. sedentary groups). The tubulointerstitial injury was lower in interventions groups (SOE, TO and TOE vs. SO), with potentialized benefits in the trained groups. CONCLUSIONS: Enalapril combined with CET attenuated BPV and baroreflex dysfunctions, probably impacting on end-organ damage, as demonstrated by attenuation in the AH-induced renal inflammations, oxidative stress and morphofunctional impairments in postmenopausal rats.

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OBJECTIVE: This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ). METHODS: Female spontaneously hypertensive rats (SHR) (150-200g, 90 days old) were distributed into 5 hypertensive groups (n = 7-8 rats/group): control (C), ovariectomized (O), ovariectomized treated with HCTZ (OH), ovariectomized submitted to exercise training (OT) and ovariectomized submitted to exercise training and treated with HCTZ (OTH). Ovarian hormone deprivation was performed through bilateral ovariectomy. HCTZ (30mg/kg/day) and concurrent exercise training (3d/wk) were conducted lasted 8 weeks. Arterial pressure (AP) was directly recorded. Cardiac effort was evaluated using the rate-pressure product (RPP = systolic AP x heart rate). Vasopressin V1 receptor antagonist, losartan and hexamethonium were sequentially injected to evaluate the vasopressor systems. Inflammation and oxidative stress were evaluated in cardiac tissue. RESULTS: In addition to the reduction in AP, trained groups improved RPP, AP variability, bradycardic (OT: -1.3 ± 0.4 and OTH: -1.6 ± 0.3 vs. O: -0.6 ± 0.3 bpm/mmHg) and tachycardic responses of baroreflex sensitivity (OT: -2.4 ± 0.8 and OTH: -2.4 ± 0.8 vs. O: -1.3 ± 0.5 bpm/mmHg), NADPH oxidase and IL-10/TNF-α ratio. Hexamethonium injection revealed reduced sympathetic contribution on basal AP in OTH group (OTH: -49.8 ± 12.4 vs. O: -74.6 ± 18.1 mmHg). Furthermore, cardiac sympathovagal balance (LF/HF ratio), IL-10 and antioxidant enzymes were enhanced in OTH group. AP variability and baroreflex sensitivity were correlated with systolic AP, RPP, LF/HF ratio and inflammatory and oxidative stress parameters. CONCLUSION: The combination of HCTZ plus concurrent exercise training induced additional positive adaptations in cardiovascular autonomic control, inflammation and redox balance in ovariectomized SHR. Therefore, combining exercise and medication may represent a promising strategy for managing classic and remaining cardiovascular risks in AH.

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Alzheimer's Disease (AD) is a neurodegenerative condition characterized by progressive memory loss and other affected cognitive functions. Pharmacological therapy of AD relies on inhibitors of the enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), offering only a palliative effect and being incapable of stopping or reversing the neurodegenerative process. However, recent studies have shown that inhibiting the enzyme ß-secretase 1 (BACE-1) may be able to stop neurodegeneration, making it a promising target. Considering these three enzymatic targets, it becomes feasible to apply computational techniques to guide the identification and planning of molecules capable of binding to all of them. After virtually screening 2119 molecules from a library, 13 hybrids were built and further screened by triple pharmacophoric model, molecular docking, and molecular dynamics (t = 200 ns). The selected hybrid G meets all stereo-electronic requirements to bind to AChE, BChE, and BACE-1 and offers a promising structure for future synthesis, enzymatic testing, and validation.

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The inverse relationship between exercise intensity and affective valence is well established for continuous exercise but not for high-intensity interval exercise (HIIE). The objective was to verify the dose-response relationship between exercise intensity and affective valence in HIIE sessions. Eleven young men underwent a vigorous-intensity continuous exercise (VICE) and three HIIE sessions at the same average intensity (70% of peak power-WPeak) and duration (20 min) but with different amplitudes: 10 × [1 min at 90% WPeak/1 min at 50% WPeak]-HIIE-90/50; 10 × [1 min at 100% WPeak/1 min at 40% WPeak]-HIIE-100/40; 10 × [1 min at 110% WPeak/1 min at 30% WPeak]-HIIE-110/30. During the exercise sessions, psychophysiological variables were recorded (VO2, VCO2, heart rate, perceived exertion CR10, and Feeling Scale (FS)). Higher correlations were found between CR10 and FS for all conditions (VICE = -0.987; HIIE-90/50 = -0.873; HIIE-100/40 = -0.908; HIIE-110/30 = -0.948). Regarding the physiological variables, the %HRMax presented moderate inverse correlations with FS for all exercise conditions (VICE = -0.867; HIIE-90/50 = -0.818; HIIE-100/40 = -0.837; HIIE-110/30 = -0.828) while the respiratory variables (%VO2Peak and %VCO2Peak) presented low-to-moderate correlations only for VICE, HIIE-90/50, and HIIE-100/40 (ranging from -0.523 to -0.805). Poor correlations were observed between the %VO2Peak (r = -0.293) and %VCO2Peak (r = -0.020) with FS. The results indicated that perceived exertion is more sensible than physiological variables to explain the intensity-affective valence relationship in HIIE sessions. RPE should be used for HIIE prescription with a focus on affect.

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The growth of videos in our digital age and the users' limited time raise the demand for processing untrimmed videos to produce shorter versions conveying the same information. Despite the remarkable progress that summarization methods have made, most of them can only select a few frames or skims, creating visual gaps and breaking the video context. This paper presents a novel weakly-supervised methodology based on a reinforcement learning formulation to accelerate instructional videos using text. A novel joint reward function guides our agent to select which frames to remove and reduce the input video to a target length without creating gaps in the final video. We also propose the Extended Visually-guided Document Attention Network (VDAN+), which can generate a highly discriminative embedding space to represent both textual and visual data. Our experiments show that our method achieves the best performance in Precision, Recall, and F1 Score against the baselines while effectively controlling the video's output length.

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Acute myeloid leukemia (AML) comprises a heterogeneous group of hematopoietic cell neoplasms of myeloid lineage that arise from the clonal expansion of their precursors in the bone marrow, interfering with cell differentiation, leading to a syndrome of bone marrow failure. AML is a consequence of genetic and epigenetic changes (point mutations, gene rearrangements, deletions, amplifications, and arrangements in epigenetic changes that influence gene expression) in hematopoietic precursor cells, which create a clone of abnormal cells that are capable of proliferating but cannot differentiate into mature hematopoietic cells or undergo programmed cell death. The diagnosis requires more than 20% myeloid blasts in the bone marrow and certain cytogenic abnormalities. Treatment will depend on age, comorbidities, and cytogenetic risk among the most frequent.

La leucemia mieloide aguda (LMA) comprende un grupo heterogéneo de neoplasias de células hematopoyéticas de linaje mieloide que surgen de la expansión clonal de sus precursores en la médula ósea, interfiriendo con la diferenciación celular, lo que conlleva a un síndrome de falla medular. La LMA es una consecuencia de cambios genéticos y epigenéticos (mutaciones puntuales, rearreglos de genes, deleciones, amplificaciones y arreglos en cambios epigenéticos que influyen en la expression del gen) en las células hematopoyéticas precursoras, la cual crea una clona de células anormales que son capaces de proliferar, pero no se pueden diferenciar en células hematopoyéticas maduras ni sufrir una muerte celular programada. El diagnostic requiere más del 20% de blastos mieloides en médula ósea y ciertas anormalidades citogénicas. El tratamiento dependerá de la edad, comorbilidades, riesgo citogenético entre las más frecuentes.

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Abstract Acute myeloid leukemia (AML) comprises a heterogeneous group of hematopoietic cell neoplasms of myeloid lineage that arise from the clonal expansion of their precursors in the bone marrow, interfering with cell differentiation, leading to a syndrome of bone marrow failure. AML is a consequence of genetic and epigenetic changes (point mutations, gene rearrangements, deletions, amplifications, and arrangements in epigenetic changes that influence gene expression) in hematopoietic precursor cells, which create a clone of abnormal cells that are capable of proliferating but cannot differentiate into mature hematopoietic cells or undergo programmed cell death. The diagnosis requires more than 20% myeloid blasts in the bone marrow and certain cytogenic abnormalities. Treatment will depend on age, comorbidities, and cytogenetic risk among the most frequent.

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BACKGROUND: Chronic kidney disease is commonly found in patients with aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR) and has marked impact in their prognosis. It has been shown however that TAVR may improve renal function by alleviating the hemodynamic barrier imposed by AS. Nevertheless, the predictors of and clinical consequences of renal function improvement are not well established. Our aim was to assess the predictors of improvement of renal function after TAVR. METHODS: The present work is an analysis of the Brazilian Registry of TAVR, a national non-randomized prospective study with 22 Brazilian centers. Patients with baseline renal dysfunction (estimated glomerular filtration rate [eGFR] < 60mL/min/1.73m2) were stratified according to renal function after TAVR: increase >10% in eGFR were classified as TAVR induced renal function improvement (TIRFI); decrease > 10% in eGFR were classified as acute kidney injury (AKI) and stable renal function (neither criteria). RESULTS: A total of 819 consecutive patients with symptomatic severe AS were included. Of these, baseline renal dysfunction (estimated glomerular filtration rate [eGFR] < 60mL/min/1.73m2) was present in 577 (70%) patients. Considering variance in renal function between baseline and at discharge after TAVR procedure, TIRFI was seen in 197 (34.1%) patients, AKI in 203 (35.2%), and stable renal function in 177 (30.7%). The independent predictors of TIRFI were: absence of coronary artery disease (OR: 0.69; 95% CI 0.48-0.98; P = 0.039) and lower baseline eGFR (OR: 0.98; 95% CI 0.97-1.00; P = 0.039). There was no significant difference in 30-day and 1-year all-cause mortality between patients with stable renal function or TIRFI. Nonetheless, individuals that had AKI after TAVR presented higher mortality compared with TIRFI and stable renal function groups (29.3% vs. 15.4% vs. 9.5%, respectively; p < 0.001). CONCLUSIONS: TIRFI was frequently found among baseline impaired renal function individuals but was not associated with improved 1-year outcomes.

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BACKGROUND: During the SARS-CoV-2 pandemic, in order to protect the patient and to save hospital beds, cancelation of elective surgeries has become a great challenge. Considering that obesity is a chronic disease and the possible effect imposed by quarantine on weight gain with worsening rates of obesity and metabolic comorbidities, the creation of a protocol for a safe return to bariatric surgery became essential. OBJECTIVE: The aim of this study was to identify the incidence of new-onset severe acute respiratory syndrome coronavirus (SARS-CoV-2) symptoms in patients who underwent bariatric procedures during the declining curve period. SETTING: Private practice METHODS: A prospective observational cohort study was conducted and included patients with indications for bariatric surgery during the decreasing curve period of the SARS-CoV-2 pandemic who underwent surgery under a hospital security protocol. Patients were asked to answer a questionnaire and had a swab PCR test for SARS-CoV-2 detection. The primary outcome measure was the presence of 14-day and 30-day postoperative symptoms associated with COVID-19. Mortality was also analyzed. RESULTS: Three hundred patients with negative RT-PCR were operated on from May to June 2020. Seventeen patients had their surgery postponed because of a positive RT-PCR test or close contact. None of the patients developed new-onset SARS-CoV-2 symptomatic infection after 30 days of observation. No deaths were reported. Eleven had complications not related to SARS-CoV-2. CONCLUSIONS: Even though this population may have a poorer outcome when infected with SARS-CoV-2, this security protocol has shown that the procedure can be safely performed during the outbreak.

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Technological advances in sensors have paved the way for digital cameras to become increasingly ubiquitous, which, in turn, led to the popularity of the self-recording culture. As a result, the amount of visual data on the Internet is moving in the opposite direction of the available time and patience of the users. Thus, most of the uploaded videos are doomed to be forgotten and unwatched stashed away in some computer folder or website. In this paper, we address the problem of creating smooth fast-forward videos without losing the relevant content. We present a new adaptive frame selection formulated as a weighted minimum reconstruction problem. Using a smoothing frame transition and filling visual gaps between segments, our approach accelerates first-person videos emphasizing the relevant segments and avoids visual discontinuities. Experiments conducted on controlled videos and also on an unconstrained dataset of First-Person Videos (FPVs) show that, when creating fast-forward videos, our method is able to retain as much relevant information and smoothness as the state-of-the-art techniques, but in less processing time.

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Cardiovascular autonomic dysfunction is associated with end organ damage and increased risk of mortality. Menopause and metabolic syndrome increase the risk for cardiorenal complications. In this study, we investigated the effects of aerobic or resistance exercise training on autonomic control of circulation and renal oxidative stress in a model of menopause and metabolic syndrome. Female Wistar rats and spontaneously hypertensive rats (SHR) were divided into 5 groups (n = 8): control (C), hypertensive (H), and sedentary (FHO), aerobic trained (FHOTa) and resistance trained (FHOTr) oophorectomized hypertensive treated with fructose (100 mg/mL drink water for 19 weeks). The FHO group presented increased vascular sympathetic modulation (LF-SBP), impaired baroreflex sensitivity (BRS) associated with increased blood pressure (BP) when compared to the H group. Aerobic exercise training enhanced tachycardic responses, while resistance training improved bradycardic responses to BP changes, thus ameliorating BRS. Moreover, despite unchanged BP, both exercise training protocols were effective in preventing increase in LF-SBP, reduction in systemic nitric oxide bioavailability (NOx), and increase in oxidative stress in the renal tissue, by decreasing lipid and protein oxidation in renal tissue. Positive correlation between LF-SBP and renal lipoperoxidation (r = 0.63, p < 0.05), as well as a negative correlation between NOx and renal lipoperoxidation (r = -0.66, p < 0.05) were observed. In conclusion, both aerobic and resistance exercise training were effective in improving autonomic control of circulation and reducing renal oxidative stress, thus attenuating the deleterious effects induced by arterial hypertension and fructose overload in female rats after ovarian hormone deprivation.

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We open the black box of the monetary policy transmission mechanism with a granular model that considers the balance-sheet composition and network relationships of each economic agent. Though there are several well-documented channels through which monetary policy operates, we focus on the overlooked trading book channel, which arises because of adjustments in the accounting value of trading book exposures on banks' balance sheets that have to be marked to market when interest rates change. Variations in banks' net worth due these adjustments are used as input to a network model that incorporates the financial and corporate sectors. The framework permits us to determine the effects of interest rate changes on every bank and firm in the economy and any second-round (contagion) effects in the short run. We apply the model to a comprehensive database of Brazilian banks and firms from 2015 to 2020. We find that interest rate shocks affect more strongly financial stability in periods of monetary policy tightening. We also find notable asymmetric effects of positive and negative interest rate shocks in the Brazilian economy, with positive interest rate shocks affecting more financial stability. Finally, our results also suggest a non-linear relationship between interest rate changes and financial stability, reinforcing the need to mitigate monetary policy shocks through interest rate smoothing and adequate communication and transparency to society.

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The muscle co-contraction is a phenomenon characterized by the simultaneous contraction of two or more muscles around a joint. The objective of this study was to compare the antagonist co-contraction of the local and global trunk muscles during side bridge exercise, in four situations: (a) stable; (b) instability in the upper limbs with bosu; (c) instability in the upper limbs with disc and (d) double instability. The sample consisted of 20 male volunteers and data collection was performed with simple differential surface electrodes. The electromyographic activity was collected from the Rectus Abdominis (RA), Internal Oblique Abdominis (IO), Multifidus (MF) and Erector Spinae (ES). Were utilized specific routines developed in the Matlab program (Mathworks Natick, USA) to calculate the percentage of antagonist co-contraction between local (IO/MF) and global muscles (RA/ES). The collected data were submitted to parametric statistical analysis (repeated measures ANOVA) or non-parametric (Friedman). The results demonstrated that no significant differences were observed in the pattern of global and local co-contraction in the different side bridge exercises with and without unstable surface. It is concluded that the use of unstable surface in the side bridge stabilization exercise does not increase the level of co-contraction of the trunk flexor and extensor muscles compared to normal stability. However, future studies should use a longer time ofisometric contraction in trunk stabilization exercises to optimize the understanding of the effects of different unstable equipment on global and local levels of co-contraction of the trunk muscles

A cocontração muscular é um fenômeno caracterizado pela contração simultânea de dois ou mais músculos em torno de uma articulação. Objetivou-se comparar a cocontração antagonista da musculatura local e global do tronco durante o exercício prancha lateral, em quatro situações: (a) estável; (b) instabilidade no membro superior com bosu; (c) instabilidade no membro superior com disco e (d) instabilidade dupla. A amostra foi composta por 20 voluntários do gênero masculino e a coleta de dados foi realizada com eletrodos de superfície diferenciais simples. A atividade eletromiográfica foi coletada dos músculos Reto do Abdome (RA), Oblíquo Interno do Abdome (OI), Multifido (MU) e Eretor da Espinha (EE). Foram utilizadasrotinas específicas desenvolvidas no programa Matlab (Mathworks Natick, EUA) para calcular a porcentagem de cocontração antagonista entre os músculos locais (OI / MU) e globais (RA / ES). Os dados obtidos foram submetidos à análise estatística paramétrica (ANOVA medidas repetidas) ou não paramétrica (Friedman). Os resultados demonstraram que não foram observadas diferenças significativas no padrão de cocontração global e local nos distintos exercícios de prancha lateral com e sem superfície instável. Conclui-se que a utilização de superfície instável no exercício de estabilização de prancha lateral não aumenta o nível de cocontração dos músculos flexores e extensores do tronco em comparação a estabilidade normal. Todavia, futuros estudosdevem utilizar um tempo maior de contração isométrica nos exercícios de estabilização do tronco para otimizar a compreensão dos efeitos dos diferentes equipamentos instáveis sobre os níveis de cocontração global e local dos músculos do tronco.

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Resumo O trabalho recorre a depoimentos dos idosos a fim de compreender as transformações sociais ocorridas a partir da interação desse grupo populacional com os meios de comunicação. Por intermédio da dinâmica "Minha primeira vez", cada participante da Uati rememora seu primeiro contato com o aparelho celular, o computador, a TV, o cinema e o rádio. A oficina foi desenvolvida na perspectiva da educomunicação, que se trata de um campo de intervenção social nascido a partir da inter-relação comunicação e educação.

Abstract The article calls upon the elderly's testimonies in order to understand the social transformations that occurred from the interaction between this population group and the communication means. Through the workshop called "My first time", each UATI (Universidade Aberta da Terceira Idade - Open University for the Elderly) participant recalls his/her first contact with the cell phone, the computer, the TV, the cinema and the radio. The workshop was developed from the education-communication perspective, which is a field of social intervention that emerged from the interrelationship between communication and education.

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RESUMO: O objetivo deste trabalho foi determinar o número de dias e de graus-dia em que a iniciação da panícula (IP) antecede a diferenciação da panícula (DP) para cultivares de arroz de diferente duração de ciclo. Um experimento de campo foi conduzido em área de várzea, em Santa Maria, RS, e foi composto de três datas de semeadura e quatro cultivares ('IRGA 421', 'BRS Querência', 'IRGA 424' e 'SCSBRS Tio Taka') em dois anos agrícolas (2011/12 e 2012/13), no delineamento de blocos acaso, com quatro repetições. A data de ocorrência da DP foi estimada a partir das tabelas contidas em STEINMETZ et al. (2010) e, aproximadamente 14 dias antes da data estimada da DP, foram realizadas amostragens diárias de 10 plantas para determinar a IP em laboratório sob lupa de aumento de 45 vezes. Após a data de ocorrência da IP, 10 plantas foram coletadas diariamente para a análise da DP através do "ponto de algodão". A soma térmica foi calculada considerando a temperatura basal de 11ºC. As maiores diferenças entre as datas de ocorrência da IP e DP foram de 8 e 6 dias, e de 116,4 e 73,7ºC dia. Na maior parte dos resultados, as diferenças variaram entre 2 e 8 dias, e entre 23,8 e 116,4ºC dia. Concluiu-se que o período máximo que a IP antecede a DP é de oito dias, correspondendo a 116,4ºC dia, não sendo influenciado pela época de semeadura nem pelo comprimento de ciclo das cultivares.

ABSTRACT: The objective of this study was to determine the number of days and degree-days in which panicle initiation (PI) takes place before panicle differentiation (PD) for rice cultivars with different developmental cycle duration. A field experiment was carried out in a lowland area, in Santa Maria, RS, Brazil. The experiment consisted of three sowing dates and four rice cultivars ('IRGA 421', 'BRS Querência', 'IRGA 424' and 'SCSBRS Tio Taka') during two growing seasons (2011/12 and 2012/13), in a complete randomized block design with four replications. The date of PD was estimated from the tables contained in STEINMETZ et al. (2010) and around 14 days before the estimated date of PD. Ten plants were sampled daily to determine PI in a laboratory under a 45 times magnifying glass. After PI, 10 plants were sampled daily to determine PD using the "cotton ball" stage as a marker. Thermal sum was calculated considering the basal temperature of 11ºC. The greatest differences between the dates of occurrence between PI and PD were 8 and 6 days, and 116.4 and 73.7ºC day. Most of the differences varied between 2 and 8 days, and between 23.8 and 116.4ºC day. It was concluded that the maximum period that PI takes place before the PD is eight days, corresponding to 116.4ºC day, being influenced neither by sowing date nor by the length of cultivars cycle.

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Objetivo: elencar os principais diagnósticos de enfermagem em receptores de medula óssea. Metodologia: trata-se de um estudo de revisão integrativa de literatura realizada nas bases de dados indexadas a Biblioteca Virtual em Saúde, Lilacs, SciELO e nas bases PubMED, CINAHL, utilizando descritores controlados. A amostra da pesquisa foi composta por 04 artigos que utilizaram a taxonomia da NANDA para a construção dos diagnósticos, com um total de 25 inferências diagnósticas. Resultados: a partir dos achados da pesquisa foi elencado os diagnósticos de enfermagem ditos como prioritários aos receptores de medula óssea, sendo estes: Hipertermia; Risco de integridade da pele prejudicada; Medo; Débito Cardíaco Diminuído; Dor Aguda e categorizados conforme o domínio da NANDA, 02 Segurança/ Proteção; 01 Enfrentamento e tolerância ao estresse; 01 Conforto; 01 Atividade/Repouso. Conclusão: os achados da pesquisa evidenciam que a articulação dos diagnósticos de enfermagem, constitui um instrumento essencial para qualificar e direcionara assistência para as necessidades humana básicas, e assim solidificar cada vez mais o status de ciência da enfermagem.

Objective: to list the main nursing diagnoses in bone marrow recipients. Methodology: this is a study of integrative literature review conducted in indexed databases Virtual Health Library, Lilacs, SciELO and in PubMed, CINAHL, using controlled descriptors. The research sample consisted of 04 articles that used the NANDA taxonomy for building diagnostics, with a total of 25 diagnostic inferences. Results: from the findings of the research was part listed diagnoses of nursing as a priority to said bone marrow recipients, namely: Hyperthermia; Risk for impaired skin integrity; fear; Decreased cardiac output; Acute Pain and categorized according to the field of NANDA, 02 Security / Protection; 01 Coping and stress tolerance; 01 Comfort; 01 Activity / Sleep. Conclusion: the findings of the research show that the articulation of nursing diagnoses, is an essential tool to qualify and direct assistance for basic human needs, and thus increasingly solidify the status of science in nursing.

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A presente pesquisa buscou investigar o efeito de diferentes situações de estresse térmico (WBGT) sobre a frequência cardíaca (FC), gasto energético (GE), perda hídrica (PH) e consumo de água (CA) em jovens atletas de voleibol. Participaram do estudo 09 indivíduos (16,5±0,9 anos) integrantes da equipe masculina juvenil de voleibol de Umuarama. As variáveis FC, GE, PH e CA foram mensuradas durante duas sessões de treinamento (S1, S2) de volume (85min) e intensidade semelhantes, porém, com diferentes situações de estresse térmico (S1: WBGT:22,62°C; S2: WBTG: 26.55°C). O estresse térmico (WBGT) do ambiente foi determinado por um termômetro de globo modelo ITWTG2000. A FC e o GE foram mensurados por meio do equipamento Sunnto Team Pod. A PH foi calculada pela diferença entre o peso corporal no início e final das sessões de treinamento. O CA foi ?ad libitum?, porém, o volume total ingerido foi calculado usando copos descartáveis de 180ml. Para análise dos dados foi utilizado o teste T pareado (amostras dependentes). O índice de significância adotado foi de p<0,05. Após análise dos dados, observou-se similar FC (S1: 135,5±16,3bpm vs. S2: 141,5±21,5bpm), GE (S1 :994,44±267,4Kcal vs. S2: 881,2±259,6Kcal), PH (S1: 0,6±0,2Kg vs. S2: 0,4±0,3Kg) e CA (S1 :1120±345mL vs. S2: 760±429mL) nas duas sessões de treinamento. Os resultados indicam que uma pequena variação no estresse térmico do ambiente não afeta de forma marcante a FC, GE, PH e CA durante o treinamento de voleibol.

This paper sought to investigate the effect of different thermal stress situations (WBTG) on heart rate (FC), energy expenditure (GE), water loss (PH) and water intake (CA) in young volleyball players. For such, 09 young male volleyball players from Umuarama Volleyball participated of this research (16.5±0.9 years). The variables FC, GE, PH and CA were measured during two training sessions (S1, S2) with similar volume (85 min) and intensity but, with different thermal stress situations (S1: WBTG: 22.62ºC and S2 WBGT: 26.55ºC). The thermal stress (WBGT) in the training environment was determined by a globe thermometer model ITWTG2000. The FC and the GE were measured by a Suunto Team Pod. PH was calculated by the difference between the body weight at the beginning and at the end of the training sessions. The CA during the training sessions was ?ad libitum? but the total volume ingested was calculated using 180-ml plastic cups. For the data analysis, the paired T test (dependent samples) was used. The significance index adopted was p <0.05. After the analysis of the data, similar FC (S1: 135.5 ±16.3bpm vs. S2: 141.5±21.5bpm), GE (S1: 994.44±267.4 Kcal vs. S2: 881.2±259.6 Kcal), PH (S1: 0.6±0.2 Kg vs. S2: 0.4±0.3 Kg) and CA (S1: 1120±345ml vs. S2: 760±429 ml) were observed in both training sessions. The results indicate that a little variation in the environmental thermal stress does not markedly affect the FC, GE, PH and CA during volleyball training sessions.

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