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ABSTRACT Purpose: to present a scoping review protocol aimed at mapping the main characteristics of systematic reviews published in the field of Audiology, during the COVID-19 pandemic, and to evaluate the methodological quality of the studies found. Methods: a scoping review guided by the recommendations of the Joanna Briggs Institute and the PRISMA-ScR guidelines, registered on the Open Science Framework (OSF.IO/F8N7Y). The databases included PubMed, Lilacs, Scopus and Web of Science. In the first stage, two reviewers will independently evaluate the articles based on their titles and abstracts. The selected articles will be read in full based on the eligibility criteria. Any ambiguity or disagreement will be discussed and decided consensually. The results will be presented in the form of a flowchart and a narrative summary, following the PRISMA-ScR guidelines. Final Considerations: this scoping review protocol was developed in accordance with current guidelines and will seek to analyze the literature on systematic reviews in Audiology, during the pandemic, identifying gaps and existing evidence.

RESUMO Objetivo: apresentar um protocolo de revisão de escopo com o intuito de mapear as principais características das revisões sistemáticas publicadas no campo da Audiologia durante o período da pandemia da COVID-19 e avaliar a qualidade metodológica dos estudos encontrados. Métodos: trata-se de uma revisão de escopo norteada pelas recomendações do Instituto Joanna Briggs e pelo checklist PRISMA-ScR, registrada na Open Science Framework (OSF.IO/F8N7Y). As bases de dados a serem pesquisadas incluem PubMed, Lilacs, Scopus e Web of Science. Na primeira etapa, dois revisores avaliarão independentemente os artigos por títulos e resumos. Os artigos selecionados serão lidos integralmente com base nos critérios de elegibilidade. Qualquer ambiguidade ou desacordo será discutido e decidido consensualmente. Os resultados serão apresentados em forma de fluxograma e um resumo narrativo. Considerações Finais: este protocolo de revisão de escopo foi elaborado conforme diretrizes atuais e buscará analisar a literatura sobre revisões sistemáticas em Audiologia durante a pandemia, identificando lacunas e evidências existentes.

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PURPOSE: To verify the occurrence of abnormal auditory evoked potentials (AEP) tests in adult smokers. RESEARCH STRATEGIES: Systematic review of the literature according to the PRISMA guidelines, to answer the question: "Are there any changes in the AEP results in adult smokers?", PECOS strategy. Research carried out on PubMed, Embase, CINAHL, LIVIVO, Scopus, Web of Science, LILACS and Scielo databases. Additional search of gray literature: Google Scholar and ProQuest hand searching of reference lists of the included studies. SELECTION CRITERIA: Cross-sectional studies were selected, without restriction on the year of publication and language. DATA ANALYSIS: First, the titles and abstracts of all the studies were analyzed, followed by the full reading of the eligible studies. RESULTS: 898 articles were collected, after the duplicate studies were removed and after blind analysis by three researchers, 8 studies of the observational type were selected. Most studies have found an association between active smoking and changes in electrophysiological tests. CONCLUSION: Normal hearing adult smokers present alterations in short and long AEP. In the auditory brainstem response, the main altered components were the increase in waves latencies of I and III and in the interpeaks I - III and III - V, as well as a decrease in the amplitude of the waves. In Mismatch Negativity, there was a significant increase in wave amplitude and latency. In the long latency potential, P300, there was an increase in latencies and decreased amplitudes in the components N1 (in Fz) and P3.

OBJETIVO: Verificar a ocorrência de alterações nos exames de potencial evocado (PEA) auditivo em adultos fumantes normo-ouvintes. ESTRATÉGIA DE PESQUISA: Revisão sistemática da literatura de acordo com recomendações do PRISMA, buscando responder à pergunta: "Há alterações nos resultados do exame de PEA em adultos fumantes?", estratégia PECOS. Pesquisa realizada nas bases de dados PubMed, Embase, CINAHL, LIVIVO, Scopus, Web of Science, LILACS e Scielo. Busca adicional da literatura cinzenta: Google Scholar e ProQuest e busca manual das referências dos estudos incluídos. CRITÉRIOS DE SELEçÃO: Foram selecionados estudos com delineamento transversal, sem restrição do ano de publicação e idioma. ANÁLISE DOS DADOS: Primeiramente foram analisados os títulos e resumos de todos os estudos encontrados, seguido da leitura na íntegra dos estudos elegíveis. RESULTADOS: Foram obtidos 898 artigos, que após remoção dos duplicados e análise cega por três pesquisadores, foram selecionados oito trabalhos. Grande parte dos estudos encontrou uma associação entre tabagismo ativo e alterações nos testes eletrofisiológicos. CONCLUSÃO: Adultos fumantes normo-ouvintes apresentam alterações nos exames de PEA de curta e longa latência. No potencial evocado auditivo de tronco encefálico, os principais componentes alterados foram o aumento das latências das ondas I e III e nos interpicos I - III e III - V, bem como diminuição da amplitude das ondas. No Mismatch Negativity, houve aumento significativo da amplitude da onda e da latência. No potencial de longa latência, P300, houve aumento das latências e redução das amplitudes nos componentes N1 (em Fz) e P3.

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RESUMO Objetivo Verificar a ocorrência de alterações nos exames de potencial evocado (PEA) auditivo em adultos fumantes normo-ouvintes. Estratégia de pesquisa Revisão sistemática da literatura de acordo com recomendações do PRISMA, buscando responder à pergunta: "Há alterações nos resultados do exame de PEA em adultos fumantes?", estratégia PECOS. Pesquisa realizada nas bases de dados PubMed, Embase, CINAHL, LIVIVO, Scopus, Web of Science, LILACS e Scielo. Busca adicional da literatura cinzenta: Google Scholar e ProQuest e busca manual das referências dos estudos incluídos. Critérios de seleção Foram selecionados estudos com delineamento transversal, sem restrição do ano de publicação e idioma. Análise dos dados Primeiramente foram analisados os títulos e resumos de todos os estudos encontrados, seguido da leitura na íntegra dos estudos elegíveis. Resultados Foram obtidos 898 artigos, que após remoção dos duplicados e análise cega por três pesquisadores, foram selecionados oito trabalhos. Grande parte dos estudos encontrou uma associação entre tabagismo ativo e alterações nos testes eletrofisiológicos. Conclusão Adultos fumantes normo-ouvintes apresentam alterações nos exames de PEA de curta e longa latência. No potencial evocado auditivo de tronco encefálico, os principais componentes alterados foram o aumento das latências das ondas I e III e nos interpicos I - III e III - V, bem como diminuição da amplitude das ondas. No Mismatch Negativity, houve aumento significativo da amplitude da onda e da latência. No potencial de longa latência, P300, houve aumento das latências e redução das amplitudes nos componentes N1 (em Fz) e P3.

ABSTRACT Purpose To verify the occurrence of abnormal auditory evoked potentials (AEP) tests in adult smokers. Research strategies Systematic review of the literature according to the PRISMA guidelines, to answer the question: "Are there any changes in the AEP results in adult smokers?", PECOS strategy. Research carried out on PubMed, Embase, CINAHL, LIVIVO, Scopus, Web of Science, LILACS and Scielo databases. Additional search of gray literature: Google Scholar and ProQuest hand searching of reference lists of the included studies. Selection criteria Cross-sectional studies were selected, without restriction on the year of publication and language. Data analysis First, the titles and abstracts of all the studies were analyzed, followed by the full reading of the eligible studies. Results 898 articles were collected, after the duplicate studies were removed and after blind analysis by three researchers, 8 studies of the observational type were selected. Most studies have found an association between active smoking and changes in electrophysiological tests. Conclusion Normal hearing adult smokers present alterations in short and long AEP. In the auditory brainstem response, the main altered components were the increase in waves latencies of I and III and in the interpeaks I - III and III - V, as well as a decrease in the amplitude of the waves. In Mismatch Negativity, there was a significant increase in wave amplitude and latency. In the long latency potential, P300, there was an increase in latencies and decreased amplitudes in the components N1 (in Fz) and P3.

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PURPOSE: To compare the air-conduction hearing thresholds obtained with different acoustic transducers and verify the users' preferences regarding them. METHODS: This is a cross-sectional, analytical, observational study with 26 participants aged 18 to 30 years, with normal hearing and no history of exposure to high sound pressure levels or complaints of tinnitus at the time of the assessment. We surveyed their medical history and performed meatoscopy, pure-tone threshold audiometry, speech audiometry, and acoustic immittance. The auditory thresholds were surveyed twice, each time with a different type of acoustic transducer: insert (E-A-RTONE) and circumaural earphones (HDA200). The assessments were performed in a random order, with 5-minute intervals. In the end, we asked the participants which earphones they found more comfortable in the tests. The data were submitted to nonparametric statistical analysis. RESULTS: Assessing the medians in the auditory threshold survey, the circumaural earphones obtained better results at 250, 500, 2000, and 6000 Hz, while the insert earphones were better at 3000 and 4000 Hz; there were no statistical differences at 1000 and 8000 Hz. The circumaural was elected the most comfortable earphone. CONCLUSION: The circumaural earphones had better auditory thresholds at 250, 500, 2000, and 6000 Hz than the insert earphones and were reported by the patients as the most comfortable type of transducer.

OBJETIVO: Comparar os limiares auditivos por via aérea obtidos em diferentes transdutores acústicos e verificar a preferência do usuário. MÉTODO: Trata-se de um estudo observacional, analítico, transversal, realizado em 26 participantes de 18 a 30 anos, com audição dentro dos padrões de normalidade, sem histórico de exposição a altos níveis de pressão sonora ou queixa de zumbido no momento da avaliação. Realizou-se anamnese, meatoscopia, audiometria tonal liminar, logoaudiometria, e imitanciometria. Os limiares auditivos foram pesquisados duas vezes, cada uma com um tipo de transdutor acústico diferente: fone de inserção (E-A-R Tone) e fone circum-aural (HDA200). A ordem de realização foi aleatória, com intervalos de cinco minutos. Ao final, o participante foi questionado quanto ao conforto dos fones durante os testes. Os dados foram submetidos à análise estatística não paramétrica. RESULTADOS: Na pesquisa dos limiares auditivos, ao avaliar as medianas, o fone circum-aural apresentou resultados melhores em 250, 500, 2000 e 6000 Hz e o fone de inserção foi melhor em 3000 e 4000 Hz, sem diferença estatística para as frequências de 1000 e 8000 Hz. O fone circum-aural foi eleito o mais confortável. CONCLUSÃO: O fone circum-aural apresentou melhores limiares auditivos em 250, 500, 2000 e 6000Hz quando comparado ao fone de inserção, além de ser o tipo de transdutor mais confortável relatado pelos pacientes.

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RESUMO Objetivo Comparar os limiares auditivos por via aérea obtidos em diferentes transdutores acústicos e verificar a preferência do usuário. Método Trata-se de um estudo observacional, analítico, transversal, realizado em 26 participantes de 18 a 30 anos, com audição dentro dos padrões de normalidade, sem histórico de exposição a altos níveis de pressão sonora ou queixa de zumbido no momento da avaliação. Realizou-se anamnese, meatoscopia, audiometria tonal liminar, logoaudiometria, e imitanciometria. Os limiares auditivos foram pesquisados duas vezes, cada uma com um tipo de transdutor acústico diferente: fone de inserção (E-A-R Tone) e fone circum-aural (HDA200). A ordem de realização foi aleatória, com intervalos de cinco minutos. Ao final, o participante foi questionado quanto ao conforto dos fones durante os testes. Os dados foram submetidos à análise estatística não paramétrica. Resultados Na pesquisa dos limiares auditivos, ao avaliar as medianas, o fone circum-aural apresentou resultados melhores em 250, 500, 2000 e 6000 Hz e o fone de inserção foi melhor em 3000 e 4000 Hz, sem diferença estatística para as frequências de 1000 e 8000 Hz. O fone circum-aural foi eleito o mais confortável. Conclusão O fone circum-aural apresentou melhores limiares auditivos em 250, 500, 2000 e 6000Hz quando comparado ao fone de inserção, além de ser o tipo de transdutor mais confortável relatado pelos pacientes.

ABSTRACT Purpose To compare the air-conduction hearing thresholds obtained with different acoustic transducers and verify the users' preferences regarding them. Methods This is a cross-sectional, analytical, observational study with 26 participants aged 18 to 30 years, with normal hearing and no history of exposure to high sound pressure levels or complaints of tinnitus at the time of the assessment. We surveyed their medical history and performed meatoscopy, pure-tone threshold audiometry, speech audiometry, and acoustic immittance. The auditory thresholds were surveyed twice, each time with a different type of acoustic transducer: insert (E-A-RTONE) and circumaural earphones (HDA200). The assessments were performed in a random order, with 5-minute intervals. In the end, we asked the participants which earphones they found more comfortable in the tests. The data were submitted to nonparametric statistical analysis. Results Assessing the medians in the auditory threshold survey, the circumaural earphones obtained better results at 250, 500, 2000, and 6000 Hz, while the insert earphones were better at 3000 and 4000 Hz; there were no statistical differences at 1000 and 8000 Hz. The circumaural was elected the most comfortable earphone. Conclusion The circumaural earphones had better auditory thresholds at 250, 500, 2000, and 6000 Hz than the insert earphones and were reported by the patients as the most comfortable type of transducer.

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RESUMO Objetivo Avaliar os achados audiológicos de recém-nascidos expostos à sífilis materna, tratada adequadamente na gestação. Métodos Estudo de coorte única não concorrente, realizado em um hospital público. Fizeram parte da amostra recém-nascidos filhos de mães que apresentaram sorologia positiva para sífilis e que realizaram o tratamento adequado durante a gestação, compondo o grupo estudo, e recém-nascidos sem indicadores de risco para deficiência auditiva, grupo comparação. Resultados Participaram do estudo 90 recém-nascidos, sendo 41 do grupo estudo e 49 do grupo comparação. No exame de emissões otoacústicas por estímulo transiente, todos apresentaram presença de resposta bilateralmente e, na comparação das amplitudes de respostas nas bandas de frequências de 3,0 kHz, 3,5 kHz e 4,0 kHz observou-se menor amplitude de resposta no grupo exposto, com diferença estatisticamente significativa para a frequência de 4 kHz à direita. Na análise das respostas do exame de potencial evocado auditivo de tronco encefálico, não se observou assimetria de resposta entre as orelhas que sugerisse alteração retrococlear e nem diferenças nos valores das latências absolutas ou intervalos interpicos, entre os grupos. Conclusão As respostas eletroacústicas foram discretamente inferiores nos recém-nascidos exposto à sífilis materna, enquanto que as respostas eletrofisiológicas foram semelhantes às encontradas na população de baixo risco para deficiência auditiva.

ABSTRACT Purpose To evaluate the audiological findings of newborns exposed to maternal syphilis, properly treated during pregnancy. Methods This was a single, non-concurrent cohort study conducted in a public hospital. The sample included newborns whose mothers had positive syphilis serology and who underwent adequate treatment during pregnancy, composing the study group, and newborns without risk indicators for hearing loss, as a comparison group. Results Ninety newborns participated in the study, 41 were the study group and 49 were the comparison group. In the transient evoked otoacoustic emissions test, all newborns showed a bilateral response, and when comparing the amplitudes of responses in the 3.0 kHz, 3.5 kHz and 4.0 kHz frequency bands, a smaller amplitude of response in the studied group with a statistically significant difference for the frequency of 4 kHz on the right was observed. An analysis of the response of the brainstem auditory evoked potential test showed no asymmetry of response between the ears that suggest a retrocochlear alteration, nor difference in the values of absolute latencies or interpeak intervals between groups. Conclusion The electroacoustic responses were slightly lower in newborns exposed to maternal syphilis, whereas their electrophysiological responses were similar to those found in the population at low risk for hearing loss.

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ABSTRACT Purpose: to survey the national and international literature on the impacts of the coronavirus infection on the auditory system. Methods: an integrative review with search in the BIREME, PubMed, Scopus, and Web of Sciences databases. Inclusion criteria: articles in Portuguese and English whose subject was the coronavirus infection and its effects on the auditory system. Exclusion criteria: information from books and/or chapters, letters to editors, review articles, experience reports. The search strategy was based on the following combined descriptors, respectively in Portuguese and English: "Infecções por coronavírus", "Audição", "Perda auditiva", "Coronavirus infections", "Hearing", "Hearing Loss". Results: out of 43 articles found, two approached the issue. The first study assessed 20 patients that tested positive for COVID-19, though asymptomatic, who underwent pure-tone threshold audiometry and otoacoustic emissions. A significant increase in the auditory thresholds at high frequencies and a smaller response amplitude in the transient evoked otoacoustic emissions of those who tested positive for COVID-19 were observed when compared to that of controls. The second study reported the case of an asymptomatic 35-year-old COVID-19 female patient, who complained of otalgia and tinnitus, after being contaminated. The pure-tone threshold audiometry and tympanometry indicated mild unilateral (right ear) conductive hearing loss, with a type B tympanometric curve on that side. Conclusion: the studies included in this review showed different consequences of COVID-19 on hearing, with possible impairments on the sensory and mechanical structures of the auditory system. The knowledge of COVID-19 is limited, and further studies on its real impact on the auditory system are necessary.

RESUMO Objetivo: realizar um levantamento da literatura nacional e internacional sobre os impactos da infecção por coronavírus no sistema auditivo. Métodos: revisão integrativa com pesquisa nas bases de dados Bireme, PubMed, Scopus e Web of Sciences. Critérios de inclusão: artigos em português e em inglês que tinham como tema a infecção por coronavírus e seus efeitos no sistema auditivo. Critérios de exclusão: informações de livros e/ou capítulos, cartas ao editor, artigos de revisões e de relatos de experiência. Para a estratégia de busca, utilizou-se a combinação dos descritores em português e em inglês, respectivamente: "Infecções por coronavírus", "Audição", "Perda auditiva", "Coronavirus infections", "Hearing", "Hearing Loss". Resultados: dos 43 artigos encontrados, dois abordaram o tema proposto. O primeiro estudo avaliou 20 pacientes que testaram positivo para COVID-19, porém assintomáticos, esses realizaram audiometria tonal liminar e emissões otoacústicas. Observou-se como resultado um aumento significativo dos limiares auditivos nas altas frequências e menor amplitude de resposta no exame de emissões otoacústicas evocadas por estímulo transiente, quando comparados ao grupo controle. O segundo estudo relatou o caso de uma paciente de 35 anos de idade com COVID-19 assintomática, que apresentou queixa de otalgia e zumbido após a contaminação. A audiometria tonal liminar e timpanometria indicaram perda auditiva do tipo condutiva de grau leve unilateral à direita com curva timpanométrica do tipo B deste lado. Conclusão: os estudos incluídos mostraram diferentes repercussões da COVID-19 na audição, com possíveis acometimentos nas estruturas sensoriais e mecânicas do sistema auditivo. O conhecimento sobre a COVID-19 é limitado e mais estudos primários sobre seu real impacto no sistema auditivo são necessários.

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ABSTRACT Purpose: to survey the national literature after the universal neonatal hearing screening became compulsory, addressing aspects related to its territorial distribution, the screening procedures employed, and verify whether the internationally proposed quality indicators have been achieved. Methods: an integrative review of articles indexed in the BIREME, PubMed, and Scopus databases. Inclusion criteria: Articles in Portuguese and English published after Law 12,303/2010 was passed, whose theme was the neonatal hearing screening in Brazil. Exclusion criteria: Information from books and/or chapters, integrative review articles or reflexive articles, studies conducted in other countries, and studies approaching a specific subpopulation. The search strategy combined the following descriptors in Portuguese and English, respectively: "Triagem Neonatal", "Perda auditiva", "Recém-nascido", "Brasil", "Neonatal Screenings", "Hearing Loss", "Newborn", "Brazil". Results: of the 224 articles found, 26 were duplicates, 38 were books or book chapters, three were integrative reviews, 20 were studies conducted in other countries, and 120 were either reflexive articles or studies approaching a specific subpopulation. The final sample comprised 17 articles that addressed the proposed theme. Conclusion: the South and Southeast Regions of Brazil concentrated most of the programs, and the main technique employed was the evoked otoacoustic emissions. Two quality indicators were achieved: performance rates within the first month of life, and diagnosis referral rates. However, the coverage rates remained below the expectation, and there were still high retest referral rates, high nonattendance rates in the subsequent stages, low satisfactory retest result rates, and a large number of "fail" in the two screening stages.

RESUMO Objetivo: realizar um levantamento da literatura nacional após a obrigatoriedade da triagem auditiva neonatal universal abordando aspectos relacionados à sua distribuição territorial, aos procedimentos adotados para a triagem, assim como verificar se os indicadores de qualidade sugeridos internacionalmente foram alcançados. Métodos: revisão integrativa com pesquisa de artigos indexados nas bases de dados Bireme, PubMed e Scopus. Critérios de inclusão: artigos em português e em inglês publicados após a sanção da Lei 12.303/2010 e que apresentassem como tema a Triagem Auditiva Neonatal no Brasil. Critérios de exclusão: informações de livros e/ou capítulos, artigos de revisões integrativas ou artigos de reflexão, estudos feitos em outros países e estudos referentes a uma subpopulação específica. Para a estratégia de busca, foi utilizada a combinação dos seguintes descritores em português e em inglês, respectivamente: "Triagem Neonatal", "Perda auditiva", "Recém-nascido", "Brasil", "Neonatal Screenings", "Hearing Loss", "Newborn", "Brazil". Resultados: dos 224 artigos encontrados, 26 eram duplicatas, 38 eram livros ou capítulos de livros, três eram revisões integrativas, 20 eram estudos realizados em outros países e 120 eram artigos de reflexão ou estudos referentes a uma subpopulação específica. A amostra final, foi composta de 17 artigos que abordaram o tema proposto. Conclusão: as regiões Sul e Sudeste concentram o maior número de programas, e a principal técnica foi a das emissões otoacústicas evocadas. Em se tratando dos indicadores de qualidade, os dois alcançados foram os índices de realização em até um mês de vida e o de encaminhamento para o diagnóstico. Entretanto, as taxas de cobertura continuam aquém do esperado, e ainda há índices elevados no encaminhamento para reteste, grande evasão nas etapas subsequentes, baixo índice de resultado satisfatório no reteste e grande número de "falha" nas duas etapas da triagem.

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INTRODUÇÃO: Diversos são os indicadores de risco para deficiência auditiva. O índice de Apgar, quando menor que quatro no primeiro minuto e/ou menor que seis no quinto minuto de vida, é considerado um indicador de risco para surdez. Tais valores estão associados à ocorrência de asfixia, que é uma das causas mais comuns de lesão e morte celular e, desta forma, algum dano ao sistema auditivo pode ocorrer. OBJETIVO: Verificar a influência do indicador de risco para deficiência auditiva, Apgar baixo, na primeira avaliação auditiva do neonato. MÉTODOS: Estudo clínico transversal, realizado em hospital público no período de janeiro de 2012 a dezembro de 2016. Os neonatos realizaram a avaliação audiológica por meio do exame de emissões otoacústicas evocadas por estímulo transiente (EOE-t). A relação entre Apgar baixo e "falha" nas EOE-t foi analisada por regressão logística simples. RESULTADOS: Foram avaliados 6.301 neonatos, desses 15,82% (n=996) tinham indicadores de risco para deficiência auditiva e 6,57% (n=415) obtiveram Apgar baixo. Apresentaram falha no exame de EOE-t, uni ou bilateral, 6,5% (n=415) dos neonatos triados. Outros indicadores de risco aumentaram as chances de "falha" na EOE-t, porém o Apgar baixo, isoladamente, aumentou as chances de "falha" em neonatos com peso ao nascimento maior que 1.500 g (OR: 1,58; p=0,02) e sem hemorragia peri-intraventricular (OR: 1,56; p=0,01). CONCLUSÃO: O índice de Apgar baixo foi o principal causador de "falha" na primeira avaliação auditiva dentre os neonatos com peso maior de 1.500 g e sem hemorragia peri-intraventricular.

INTRODUCTION: There are several risk indicators for hearing loss. The Apgar score, when less than four in the first minute and/or less than six in the fifth minute of life, is considered an indicator of risk for hearing loss. Such values are associated with the occurrence of asphyxia, which is one of the most common causes of cell death and injury and, therefore, some damage to the auditory system may occur. OBJECTIVE: To check the influence of risk indicator for hearing loss, low Apgar, in the first neonatal hearing evaluation. METHODS: Cross-sectional study conducted in a public hospital from January 2012 to December 2016. The neonates underwent hearing evaluation by examining transient-evoked otoacoustic emissions (TEOAE). The relation between low Apgar and "refer" in the TEOAE was analyzed by simple logistic regression. RESULTS: A total of 6,301 newborns were evaluated, of which 15.82% (n=996) had risk indicators for hearing loss and 6.57% (n=415) had with low Apgar. 6.5% (n=415) of the neonates screened showed failure of the EOE-t test, uni or bilateral. Others risk indicators increased the chances of "refer"; however, the presence of low Apgar alone increased the chances of "refer" in the TEOAE in newborns with birth weight greater than 1,500 g (OR: 1.58; p=0.02) and without peri-intraventricular hemorrhage (OR: 1.56; p=0.01). CONCLUSION: The low Apgar score was the mainly cause of "refer" on the first hearing evaluation among neonates with with birth weight greater than 1,500 g and without peri-intraventricular hemorrhage.

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Abstract Introduction For the population with risk factors for hearing loss, the first option to assess the hearing status is the performance of the automated brainstem auditory evoked potential (BAEP) test because of its efficacy in identifying retrocochlear hearing loss. Objective To verify the outcomes of automated BAEP performed in different settings as well as the factors associated with the prevalence of hearing impairment. Methods Cross-sectional study conducted from October of 2014 to May of 2015. The sample consisted of 161 infants with at least one risk factor for hearing loss who underwent automated BAEP during the hospital stay or at the outpatient clinic. After 30 days, the altered cases were referred for BAEP diagnosis. Results One hundred and thirty-eight infants (86%) had a result of "pass" and 23 (14%) of "failure" in the automated BAEP. There was no statistically significant difference in the rate of "referred" results between examinations performed in different settings. The infants' ages did not influence the number of abnormal cases. All of the 23 infants who presented a "referred" result in the automated BAEP, unilateral or bilateral, were sent for BAEP diagnosis, and out of these, 9 (39%) remained with at least some degree of alteration. The average age of diagnosis was 2.7 months. Conclusion The results of the automated BAEP were similar when performed during hospitalization or after discharge. Neither the age at the examination nor the gender of the patient influenced the prevalence of hearing loss.

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Introduction For the population with risk factors for hearing loss, the first option to assess the hearing status is the performance of the automated brainstem auditory evoked potential (BAEP) test because of its efficacy in identifying retrocochlear hearing loss. Objective To verify the outcomes of automated BAEP performed in different settings as well as the factors associated with the prevalence of hearing impairment. Methods Cross-sectional study conducted from October of 2014 to May of 2015. The sample consisted of 161 infants with at least one risk factor for hearing loss who underwent automated BAEP during the hospital stay or at the outpatient clinic. After 30 days, the altered cases were referred for BAEP diagnosis. Results One hundred and thirty-eight infants (86%) had a result of "pass" and 23 (14%) of "failure" in the automated BAEP. There was no statistically significant difference in the rate of "referred" results between examinations performed in different settings. The infants' ages did not influence the number of abnormal cases. All of the 23 infants who presented a "referred" result in the automated BAEP, unilateral or bilateral, were sent for BAEP diagnosis, and out of these, 9 (39%) remained with at least some degree of alteration. The average age of diagnosis was 2.7 months. Conclusion The results of the automated BAEP were similar when performed during hospitalization or after discharge. Neither the age at the examination nor the gender of the patient influenced the prevalence of hearing loss.

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OBJECTIVE: To verify the effect of peri-intraventricular hemorrhage on the auditory pathway of preterm infants. METHOD: It is a non-concurrent cohort study. This study was conducted in a tertiary public. Preterm infants with peri-intraventricular hemorrhage comprised the study group, and preterm infants without peri-intraventricular hemorrhage were included as a comparison group, both were similar in relation to gestational age and risk indicators for hearing loss. Participants had to meet the following inclusion criteria: have been born at the study site, presence of otoacoustic emissions by transient stimulus in both ears and brainstem auditory evoked potentials with all components bilaterally identified. RESULTS: 44 infants with an average age of 3 months with peri-intraventricular hemorrhage and 2,6 months without peri-intraventricular hemorrhage met the inclusion criteria. Regarding the brainstem auditory evoked potentials results, a significant increase was observed in absolute latency values of waves I, III and V, as well as in the interpeak intervals I-III and I-V, bilaterally, in infants with peri-intraventricular hemorrhage. CONCLUSION: This study concluded that infants with peri-intraventricular hemorrhage presented a delay in the neural conduction of sound, which justifies the monitoring of the auditory function in these infants during the period of language development.

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RESUMO Objetivo Determinar os indicadores de risco para deficiência auditiva, que afetam as diferentes etapas de avaliação de um programa de triagem auditiva neonatal universal. Métodos Estudo retrospectivo longitudinal de triagem auditiva neonatal, realizado em 832 neonatos nascidos em hospital público terciário, no período de janeiro a dezembro de 2012. O exame de Emissões Otoacústicas Evocadas por Estímulo Transiente foi realizado na primeira avaliação auditiva de todos os neonatos. Nos casos de "falha" na primeira avaliação, foi aplicado um reteste e, quando houve a permanência da "falha", foi realizado o Potencial Evocado Auditivo de Tronco Encefálico (PEATE). Os neonatos com indicador de risco para deficiência auditiva realizaram o PEATE independente do resultado das emissões otoacústicas. Resultados A presença de, ao menos, um indicador de risco para deficiência auditiva, associado ou não a malformações craniofaciais, síndromes genéticas e peso menor que 1500 g ao nascimento, aumentaram significativamente as chances de "falha" na avaliação por emissões otoacústicas. Meningite e malformações craniofaciais aumentaram de maneira expressiva as chances de PEATE alterado. Dois neonatos com emissões otoacústicas normais apresentaram diagnóstico de neuropatia auditiva. Conclusão A malformação craniofacial é um indicador fortemente associado ao diagnóstico da surdez, independente de a triagem auditiva ter sido realizada por emissões otoacústicas ou por PEATE em suas diferentes etapas, o que justifica o monitoramento contínuo e sistemático do serviço de triagem, na busca da melhoria da qualidade do programa de saúde auditiva do neonato.

ABSTRACT Purpose To determine risk indicators for hearing loss affecting different evaluation steps of a universal newborn hearing screening program. Methods Longitudinal, retrospective study of newborn hearing screening in a tertiary public hospital, including 832 newborns born between January and December 2012. Transient evoked otoacoustic emissions were measured at the first hearing evaluation in all newborns and retested in cases of "failure". When a "failure" result persisted, auditory brainstem responses (ABR) was performed. All newborns with risk indicator for hearing loss were evaluated with ABR screening regardless of the outcome of the otoacoustic emissions test. Results The presence of at least one risk indicator for hearing loss, associated or not with craniofacial malformations, genetic syndromes and birth weight below 1500 g significantly increased the chances of "failure" in the otoacoustic emissions test. Meningitis and craniofacial malformations significantly increased the odds of an abnormal ABR. Two newborns with normal otoacoustic emissions were diagnosed with auditory neuropathy. Conclusion Craniofacial malformation was an indicator strongly associated with a diagnosis of deafness, regardless of the hearing screening being performed by otoacoustic emissions or ABR at different steps of a universal newborn hearing screening program. This finding justifies continuous and systematic monitoring of the screening service seeking quality improvement of the newborn health hearing program.

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INTRODUCTION: Early diagnosis of hearing loss minimizes its impact on child development. We studied factors that influence the effectiveness of screening programs.OBJECTIVE: To investigate the relationship between gender, weight at birth, gestational age, risk factors for hearing loss, venue for newborn hearing screening and "pass" and "fail" results in the retest.METHODS: Prospective cohort study was carried out in a tertiary referral hospital. The screening was performed in 565 newborns through transient evoked otoacoustic emissions in three admission units before hospital discharge and retest in the outpatient clinic. Gender, weight at birth, gestational age, presence of risk indicators for hearing loss and venue for newborn hearing screening were considered.RESULTS: Full-term infants comprised 86% of the cases, preterm 14%, and risk factors for hearing loss were identified in 11%. Considering the 165 newborns retested, only the venue for screening, Intermediate Care Unit, was related to "fail" result in the retest.CONCLUSIONS: Gender, weight at birth, gestational age and presence of risk factors for hearing loss were not related to "pass" and/or "fail" results in the retest. The screening performed in intermediate care units increases the chance of continued "fail" result in the Transient Otoacoustic Evoked Emissions test.

INTRODUÇÃO: O diagnóstico precoce da surdez minimiza impactos no desenvolvimento infantil. Fatores que interferem na efetividade dos programas de triagem são estudados.OBJETIVO: Verificar a relação entre sexo, peso ao nascimento, idade gestacional, presença de risco para deficiência auditiva, local de realização da triagem auditiva neonatal e resultados "passa" e "falha" no reteste.MÉTODO: Estudo de coorte prospectiva, em hospital de referência terciário. A triagem foi realizada em 565 neonatos, por meio das emissões otoacústicas evocadas transientes, em três unidades de internação antes da alta hospitalar e o reteste, no ambulatório. Sexo, peso ao nascimento, idade gestacional, presença de indicadores de risco para deficiência auditiva e local de realização do exame foram considerados.RESULTADOS: Nasceram a termo 86%, prematuros 14% e risco para deficiência auditiva, 11%. Dentre os 165 neonatos retestados, apenas o local de realização do exame, Unidade de Cuidados Intermediários, se relacionou com manutenção da "falha" no reteste.CONCLUSÕES: Sexo, peso ao nascimento, idade gestacional e presença de indicadores de risco para deficiência auditiva não se relacionaram com "passar" e/ou "falhar" no reteste. A realização do exame em unidades de cuidados intermediários aumenta a chance de permanência de "falha" no exame de Emissões Otoacústicas Evocadas Transientes.

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INTRODUCTION: Early diagnosis of hearing loss minimizes its impact on child development. We studied factors that influence the effectiveness of screening programs. OBJECTIVE: To investigate the relationship between gender, weight at birth, gestational age, risk factors for hearing loss, venue for newborn hearing screening and "pass" and "fail" results in the retest. METHODS: Prospective cohort study was carried out in a tertiary referral hospital. The screening was performed in 565 newborns through transient evoked otoacoustic emissions in three admission units before hospital discharge and retest in the outpatient clinic. Gender, weight at birth, gestational age, presence of risk indicators for hearing loss and venue for newborn hearing screening were considered. RESULTS: Full-term infants comprised 86% of the cases, preterm 14%, and risk factors for hearing loss were identified in 11%. Considering the 165 newborns retested, only the venue for screening, Intermediate Care Unit, was related to "fail" result in the retest. CONCLUSIONS: Gender, weight at birth, gestational age and presence of risk factors for hearing loss were not related to "pass" and/or "fail" results in the retest. The screening performed in intermediate care units increases the chance of continued "fail" result in the Transient Otoacoustic Evoked Emissions test.

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INTRODUCTION: Patients undergoing hematopoietic stem cell transplantation receive high doses of chemotherapy and radiotherapy, which cause severe immunosuppression. OBJECTIVE: To report an oral disease management protocol before and after hematopoietic stem cell transplantation. METHODS: A prospective study was carried out with 65 patients aged > 18 years, with hematological diseases, who were allocated into two groups: A (allogeneic transplant, 34 patients); B (autologous transplant, 31 patients). A total of three dental status assessments were performed: in the pre-transplantation period (moment 1), one week after stem cell infusion (moment 2), and 100 days after transplantation (moment 3). In each moment, oral changes were assigned scores and classified as mild, moderate, and severe risks. RESULTS: The most frequent pathological conditions were gingivitis, pericoronitis in the third molar region, and ulcers at the third moment assessments. However, at moments 2 and 3, the most common disease was mucositis associated with toxicity from the drugs used in the immunosuppression. CONCLUSION: Mucositis accounted for the increased score and potential risk of clinical complications. Gingivitis, ulcers, and pericoronitis were other changes identified as potential risk factors for clinical complications. .

INTRODUÇÃO: Pacientes submetidos a transplante de células hematopoiéticas recebem altas doses de quimioterapia e radioterapia que podem causar imunossupressão e doenças orais graves. OBJETIVO: Apresentar um protocolo de avaliação de doenças orais antes e após transplante de células hematopoiéticas. MÉTODO: Estudo clínico prospectivo de 65 pacientes com idade acima de 18 anos, com doenças hematológicas submetidas a transplante de células hematopoiéticas, divididos em dois grupos: A (transplante alogênico, 34 pacientes) e B (transplante autólogo). Foram realizadas três avaliações odontológicas: período antes do transplante (momento 1), uma semana (momento 2) e 100 dias após o transplante (momento 3). Em cada momento as alterações orais foram pontuadas e classificadas como leve, moderada e grave. RESULTADOS: As alterações orais mais frequentes foram: gengivite, pericoronite do terceiro molar e úlceras. Entretanto nos momentos dois e três a principal doença foi a mucosite associada a toxicidades das drogas usadas na imunossupressão. CONCLUSÃO: Mucosite foi principal alteração, com a pontuação mais alta e com maior risco de complicações. Gengivites, úlceras e pericoronites foram outras alterações com risco menor de complicações. .

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INTRODUCTION: Patients undergoing hematopoietic stem cell transplantation receive high doses of chemotherapy and radiotherapy, which cause severe immunosuppression. OBJECTIVE: To report an oral disease management protocol before and after hematopoietic stem cell transplantation. METHODS: A prospective study was carried out with 65 patients aged>18 years, with hematological diseases, who were allocated into two groups: A (allogeneic transplant, 34 patients); B (autologous transplant, 31 patients). A total of three dental status assessments were performed: in the pre-transplantation period (moment 1), one week after stem cell infusion (moment 2), and 100 days after transplantation (moment 3). In each moment, oral changes were assigned scores and classified as mild, moderate, and severe risks. RESULTS: The most frequent pathological conditions were gingivitis, pericoronitis in the third molar region, and ulcers at the third moment assessments. However, at moments 2 and 3, the most common disease was mucositis associated with toxicity from the drugs used in the immunosuppression. CONCLUSION: Mucositis accounted for the increased score and potential risk of clinical complications. Gingivitis, ulcers, and pericoronitis were other changes identified as potential risk factors for clinical complications.

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Objetivo: Avaliar os efeitos da asfixia perinatal sobre os níveis de resposta das emissões otoacústicas por estímulo transiente em lactentes. Métodos: Foi realizado, para comparação, o registro das emissões otoacústicas transientes em 154 neonatos: 54 bebês que sofreram asfixia perinatal, medida pela escala de Apgar e diagnóstico médico ao nascimento, e 100 bebês sem risco. Escores abaixo de 4 no primeiro minuto e/ou menores que 6 no quinto minuto foram considerados "Apgar baixo". A análise estatística do conjunto de dados foi efetuada utilizando-se os testes não paramétricos de Kruskal, Wilcoxon e Mann-Whitney. Resultados: Foram observados menores níveis de resposta nas emissões otoacústicas transientes para o grupo que sofreu asfixia perinatal, com valores estatisticamente significantes para as frequências de 2000, 3000 e 4000Hz na orelha direita e 2000 e 4000Hz na orelha esquerda. Conclusão: A análise das características intrínsecas do exame de emissões otoacústicas transientes mostrou baixo desempenho das células ciliadas externas em neonatos que tiveram asfixia perinatal, o que pode afetar o desenvolvimento das habilidades auditivas nessa população...

Objective: To evaluate the effects of perinatal asphyxia on the level of the response to transient otoacoustic emissions in infants. Methods: Otoacoustic emissions in 154 neonates were performed: 54 infants who suffered asphyxia at birth, measured by Apgar score and medical diagnosis, and 100 infants without risk were compared. Scores less than 4 in the first minute and/or less than 6 in the fifth minute were considered as "low Apgar". Statistical analysis of the data was performed using the Kruskal, Wilcoxon, and Mann-Whitney nonparametric tests. Results: Lower levels of response were observed in transient otoacoustic emission in the group that suffered perinatal asphyxia, with significant values for the frequencies 2,000, 3,000, and 4,000 Hz in the right ear, and 2,000 and 4,000 Hz in the left ear. Conclusions: The analysis of the intrinsic characteristics of the otoacoustic emissions evidenced low performance of outer hair cells in neonates who had perinatal asphyxia, which may affect the development of listening skills in this population...

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INTRODUCTION: Chronic kidney disease (CKD) is defined as the presence of renal injury that leads to the slow and progressive loss of kidney function. AIM: To compare audiological tests between patients with CKD receiving different types of treatment. MATERIAL AND METHOD: This was a clinical and experimental study. Groups were divided according to treatment: hemodialysis (n = 35), peritoneal dialysis (n = 15), and conservative (n = 51), and were compared to 27 healthy controls. Patients older than 60 years; those with congenital hearing loss, genetic syndromes, and middle-ear infections; and those who had been submitted to a kidney transplant were excluded. Audiologic evaluation included pure-tone audiometry, transient evoked otoacoustic emissions, and auditory brainstem response (ABR). The variables considered were gender, age, diagnosis of arterial hypertension, time since the diagnosis of diabetes and hypertension, CKD stage, duration of CKD, and duration of treatment. RESULTS: The variables age, presence of arterial hypertension, and time of CKD were statistically significant and controlled. The auditory thresholds measured by pure-tone threshold audiometry were worse for the conservative treatment group, and the III-V interval of the ABR of the conservative treatment group was significantly greater than that of the hemodialysis groups. CONCLUSION: The conservative treatment group presented worse audiological tests, regardless of hypertension and diabetes, reinforcing that patients need to undergo a complete hearing assessment for better understanding of the disease and its effects on the auditory system.

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Introdução: Doença renal crônica (DRC) é definida pela presença de lesão renal levando à perda lenta e progressiva da função renal. Objetivo: Comparar testes auditivos entre pacientes com DRC submetidos a diferentes método de tratamento. Material e método: Estudo clínico transversal. Os grupos foram divididos de acordo com o método de tratamento: hemodiálise (n = 35), diálise peritoneal (n =15), conservador (n = 51) e 27 pacientes saudáveis (controle). Pacientes com idade superior a 60 anos, perda auditiva congênita, síndromes genéticas, infecções de orelha média e transplante renal foram excluídos da pesquisa. A avaliação audiológica incluiu audiometria tonal, emissões otoacústicas evocadas transientes e Potencial Evocado Auditivo de Tronco Encefálico (PEATE); e as variáveis avaliadas foram: sexo, idade, diagnóstico de hipertensão arterial e diabetes, estádio da DRC, tempo de diagnóstico do diabetes e da hipertensão arterial, duração da DRC e do tratamento. Resultados: A idade, presença de hipertensão arterial e tempo de DRC foram estatisticamente significantes e controlados. O grupo conservador apresentou piores limiares auditivos na audiometria tonal e o intervalo III-V do PEATE significativamente maior que o da hemodiálise. Conclusão: O tratamento conservador mostrou piores resultados na avaliação auditiva, independente de diabetes e de hipertensão, reforçando que os pacientes submetidos a tratamento para DRC devem realizar avaliação auditiva completa para melhor compreensão da doença e de seus efeitos sobre o sistema auditivo. .

Introduction: Chronic kidney disease (CKD) is defined as the presence of renal injury that leads to the slow and progressive loss of kidney function. Aim: To compare audiological tests between patients with CKD receiving different types of treatment. Material and method: This was a clinical and experimental study. Groups were divided according to treatment: hemodialysis (n = 35), peritoneal dialysis (n = 15), and conservative (n = 51), and were compared to 27 healthy controls. Patients older than 60 years; those with congenital hearing loss, genetic syndromes, and middle-ear infections; and those who had been submitted to a kidney transplant were excluded. Audiologic evaluation included pure-tone audiometry, transient evoked otoacoustic emissions, and auditory brainstem response (ABR). The variables considered were gender, age, diagnosis of arterial hypertension, time since the diagnosis of diabetes and hypertension, CKD stage, duration of CKD, and duration of treatment. Results: The variables age, presence of arterial hypertension, and time of CKD were statistically significant and controlled. The auditory thresholds measured by pure-tone threshold audiometry were worse for the conservative treatment group, and the III-V interval of the ABR of the conservative treatment group was significantly greater than that of the hemodialysis groups. Conclusion: The conservative treatment group presented worse audiological tests, regardless of hypertension and diabetes, reinforcing that patients need to undergo a complete hearing assessment for better understanding of the disease and its effects on the auditory system. .

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