RESUMEN
The authors studied 30 patients with bleeding from esophageal varices due to portal hypertension. They underwent the disconnection of portal and azygos veins and splenectomy. The immediate postoperative complications were: portal thrombosis in four patients (13.3%); subphrenic abscess in two (6.6%); pulmonary embolism in one (3.3%) and esophageal perforation in one (3.3%). The manifestations of portal thrombosis were ascites, and fever (without leukocytosis). One patient with portal thrombosis who had intractable ascite was submitted to peritoneovenous shunting.
Asunto(s)
Várices Esofágicas y Gástricas/cirugía , Hemorragia Gastrointestinal/cirugía , Hipertensión Portal/cirugía , Vena Porta , Trombosis/etiología , Adolescente , Adulto , Vena Ácigos/cirugía , Várices Esofágicas y Gástricas/etiología , Femenino , Hemorragia Gastrointestinal/etiología , Humanos , Hipertensión Portal/complicaciones , Masculino , Persona de Mediana Edad , Vena Porta/cirugía , Complicaciones PosoperatoriasRESUMEN
Operative ligation of portosystemic shunts is effective in controlling chronic portosystemic encephalopathy (CPSE) but is associated with significant mortality. Review of the records of five patients with CPSE treated with radiologic occlusion procedures showed that these are suitable alternatives to surgery. Three patients had alcoholic cirrhosis, one had hepatic fibrosis from schistosomiasis, and one had post-necrotic cirrhosis. All had CPSE with progressive, severe cerebral impairment refractory to clinical treatment. Four patients had a spontaneous splenorenal shunt, and one had a surgically created mesocaval shunt (MCS). Partial splenic embolization was performed in two patients, direct shunt embolization was performed via percutaneous transhepatic portography in two other patients, and an MCS embolization was performed in one patient through the inferior vena cava. In four patients embolization controlled the CPSE. In the remaining patient it could not be evaluated because of his premature death from intraabdominal bleeding, a late complication of the procedure. Interventional radiologic procedures are effective in the control of CPSE in selected patients.
Asunto(s)
Embolización Terapéutica/métodos , Encefalopatía Hepática/terapia , Enfermedad Crónica , Embolización Terapéutica/instrumentación , Estudios de Seguimiento , Encefalopatía Hepática/diagnóstico por imagen , Encefalopatía Hepática/etiología , Humanos , Masculino , Persona de Mediana Edad , Vena Porta , Derivación Portosistémica Quirúrgica , Radiografía , Factores de Riesgo , Arteria Esplénica , Esplenomegalia/diagnóstico por imagen , Esplenomegalia/terapia , Vena Cava InferiorRESUMEN
This is a review of basic concepts on the etiopathogeny and treatment of hepatic encephalopathy focusing in more detail on the role of amino acids and neurotransmitters in precipitating the neurological picture.