RESUMEN
BACKGROUND: Many studies have investigated the efficacy and safety of matrine in treating malignant pleural effusion by thoracic perfusion. This study is an analytic value of available evidence. METHODS: Twelve studies were analyzed in this study. Pooled odds ratios and hazard ratio with 95 % confidence intervals were calculated using the fixed effects model. RESULTS: Overall response rate of matrine combined with other medications in treating malignant pleural effusion (MPE) was significantly higher than those of other medications alone (p < 0.05). Time to pleural effusion relief and quality of life were improved after the treatment of matrine combined with other medications (p < 0.05). Moreover, matrine combined with other medications had a lower incidence of adverse reactions (p < 0.05). CONCLUSIONS: Matrine combined with other medications improves the control of the malignant pleural effusions and decreases the incidence of adverse reactions.
Asunto(s)
Alcaloides/uso terapéutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias Pulmonares/prevención & control , Derrame Pleural Maligno/prevención & control , Calidad de Vida , Quinolizinas/uso terapéutico , Quimioterapia Adyuvante , Humanos , Metaanálisis como Asunto , Perfusión , Pronóstico , MatrinasRESUMEN
Objective To investigate the manage experience of “teaching clinic practical nurses”. Methods Our de-partment had taught sixty clinic practical nurses with taking stages teaching for everyone from June 2012 to May 2013. Results 98%of the practical nurses thought that the practical life was happy and what they had got from oncology was comprehensive,systematic.