RESUMEN
On the basis of clinical observation over 521 patients who underwent operations in the clinic for perforating gastric and duodenal ulcer, the authors determined the frequency of massive gastrointestinal hemorrhage (3.2%) in the early postoperative period and the mortality rate in this complication. It is shown that the performance of radical surgical interventions instead of simple closure of the perforating ulcer with sutures, in the absence of life-threatening concomitant diseases and the terminal phase of peritonitis, may improve the results of operative management of this disease.
Asunto(s)
Úlcera Duodenal/complicaciones , Gastrectomía/efectos adversos , Hemorragia Gastrointestinal/etiología , Úlcera Péptica Perforada/cirugía , Complicaciones Posoperatorias/etiología , Úlcera Gástrica/complicaciones , Vagotomía/efectos adversos , Úlcera Duodenal/cirugía , Hemorragia Gastrointestinal/cirugía , Humanos , Úlcera Péptica Perforada/etiología , Complicaciones Posoperatorias/cirugía , Úlcera Gástrica/cirugía , Técnicas de SuturaRESUMEN
Blood toxicity was estimated with the use of Tetrahymena pyriformis strain GL in patients with diffuse peritonitis. The time of the infusoria survival in the blood serum was a criterion of toxemia level. Infusoria life span was found to depend on peritonitis severity and serum concentration of medium-molecular peptides.
Asunto(s)
Peritonitis/sangre , Tetrahymena pyriformis/efectos de los fármacos , Toxemia/diagnóstico , Toxinas Biológicas/farmacología , Adulto , Animales , HumanosRESUMEN
Perforated ulcers of the duodenum complicated by peritonitis, its terminal phases excluded, should be treated by the same radical surgical interventions as other complications of the disease. The intervention must consist of vagotomy and draining operations on the stomach, its risk being not higher than risk of palliative operation of suturing the perforation.
Asunto(s)
Úlcera Duodenal/complicaciones , Úlcera Péptica Perforada/cirugía , Peritonitis/cirugía , Complicaciones Posoperatorias/cirugía , Vagotomía/métodos , Humanos , Úlcera Péptica Perforada/complicaciones , Peritonitis/etiología , Complicaciones Posoperatorias/etiología , Técnicas de Sutura , Vagotomía/efectos adversosRESUMEN
Detoxicating therapy is necessary to patients with diffuse purulent peritonitis and acute ileus. One of the simplest methods of detoxication is an intraintestinal administration of sorbents, Enterodesis in particular. The application of this drug reduced toxicity of blood serum controlled by protozoa which facilitated rapid recovery of the intestine function. Most pronounced effect of enterosorption was observed in cases with acute ileus. In more severe cases the dosage of the medicine was greater without visible sequellae in the patients. The effect of detoxication was positive as a whole.