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1.
Res Vet Sci ; 92(3): 427-34, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21561634

RESUMEN

Immune characteristics in 65 calves were evaluated in response to a Bacillus-based direct-fed microbial (DFM) provided in electrolyte scour treatment. Blood samples were analyzed for cell surface markers and α(1)-acid glycoprotein (AGP) concentration. AGP increased in scouring calves given electrolyte containing Bacillus at day 7 post-placement compared to scouring calves administered electrolyte alone and non-scouring calves, enhancing the inflammatory response for pathogen clearance. The Bacillus promotes T cell subsets including greater proportions of activated, mature cells (CD8(-)CD25(+), CD8(-)CD45RO(+), CD8(-)TCR1(+)) in calves given electrolyte containing Bacillus than scouring calves administered electrolyte alone and non-scouring calves. Also, the Bacillus may be alleviating inflammation at day 3 post-placement as the proportion of monocytes and granulocytes lacking L-selectin (CD172a(+)CD62L(-)) was greater in scouring calves given electrolyte compared to the other groups. Electrolyte containing Bacillus administered at the onset of scours influences components of innate and adaptive immune development during and following the scouring event.


Asunto(s)
Alimentación Animal/análisis , Bacillus subtilis/fisiología , Bovinos , Dieta/veterinaria , Electrólitos/uso terapéutico , Animales , Bovinos/inmunología , Enfermedades de los Bovinos/tratamiento farmacológico , Industria Lechera , Diarrea/tratamiento farmacológico , Diarrea/veterinaria , Suplementos Dietéticos , Glicoproteínas/metabolismo , Inflamación , Subgrupos Linfocitarios/efectos de los fármacos , Subgrupos Linfocitarios/fisiología , Masculino , Probióticos/uso terapéutico
2.
Probiotics Antimicrob Proteins ; 1(1): 36-44, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-26783130

RESUMEN

A Bacillus-based direct-fed microbial (DFM), Omni-BosCB™, added to an electrolyte was evaluated as a therapy for scours. Fecal shedding of presumptive Clostridium perfringens at day 7 was reduced in scouring calves treated with electrolyte plus DFM compared to scouring calves treated with electrolyte alone. Total therapeutic treatment costs during the first 2 weeks were significantly reduced by supplementing the electrolyte with the DFM: $18.69 and $21.57 for electrolyte plus DFM and electrolyte treated calves, respectively. Electrolyte treated calves experienced more severe scours than electrolyte plus DFM treated calves as additional therapy with Lactated Ringer's Solution was only necessary for electrolyte treated calves. The DFM may have other ancillary benefits after supplementation has ended, as evidenced by decreased recurrence of a second scouring event. This is the first report demonstrating efficacy of a DFM used therapeutically for mitigating calf scours. These findings have implications as alternatives to chemical interventions for disease control.

3.
Clin Nurs Res ; 7(4): 379-89, 1998 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-9919094

RESUMEN

This descriptive, correlational study examined the relationship of sleep in the hospital to the new mother's progression through Rubin's phases of taking-in and taking-hold in 120 women who had delivered vaginally. The Martell and Mitchell Postpartum Questionnaire, which measured taking-in and taking-hold, was completed the evening of delivery and the following two mornings. The Verran and Snyder-Halpern Visual Analog Sleep Scale was completed each morning. Both taking-in and taking-hold were present on the evening of delivery. There were small decreases in taking-in and small increases in taking-hold between the evening of delivery and the first morning. Sleep disturbance was high, and sleep effectiveness was low, on the first evening. Neither sleep measure was a predictor of change in taking-in or taking-hold. Findings indicate that taking-in and taking-hold are both present on the day of delivery and that increases in taking-hold take place despite high levels of sleep disturbance.


Asunto(s)
Adaptación Psicológica , Hospitalización , Conducta Materna , Madres/psicología , Trastornos Puerperales/psicología , Trastornos del Sueño-Vigilia/psicología , Adolescente , Adulto , Femenino , Humanos , Recién Nacido , Investigación Metodológica en Enfermería , Personal de Enfermería en Hospital , Atención Posnatal/psicología , Embarazo , Trastornos Puerperales/etiología , Trastornos Puerperales/enfermería , Trastornos del Sueño-Vigilia/etiología , Trastornos del Sueño-Vigilia/enfermería , Encuestas y Cuestionarios , Factores de Tiempo
4.
J Anim Sci ; 57(5): 1067-76, 1983 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-6643311

RESUMEN

One hundred sixty-eight Angus X Hereford crossbred beef steers were utilized to evaluate the influence of two levels of monensin (0 or 33 ppm) on three levels of dietary protein (9, 11 or 13% on a dry matter basis). The study was divided into a growing phase when steers received ad libitum corn silage and the needed protein supplement to supply the appropriate protein level. The finishing diet consisted of 85% dry corn and 15% corn silage plus a protein supplement to yield an 11% protein diet fed to all steers. Estimates of carcass composition were made at the beginning, at the end of the growing phase and at completion of the study. During the growing phase, growth rate (GR), dry matter intake (DMI) and efficiency of gain (F/G) were all improved (P less than .01) with increasing protein level, while monensin reduced (P less than .01) DMI and improved (P less than .01) F/G, with the greatest improvement coming on the 9% protein diet. The rate of protein deposition was increased (P less than .05) with increasing protein level and was increased (P less than .01) on the 9% protein diet while being reduced on the 13% protein diet when monensin was included in the diet. Previous protein level influenced steer performance during the finishing phase, with the steers previously receiving the 13% protein diet having the poorest GR and F/G while those having received the 11% protein diet having the highest GR.(ABSTRACT TRUNCATED AT 250 WORDS)


Asunto(s)
Peso Corporal/efectos de los fármacos , Bovinos/fisiología , Proteínas en la Dieta/metabolismo , Furanos/farmacología , Monensina/farmacología , Animales , Composición Corporal/efectos de los fármacos , Proteínas en la Dieta/administración & dosificación , Aditivos Alimentarios , Masculino , Monensina/administración & dosificación
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