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CONTEXT: Certain medications have higher chances of causing adverse effects in geriatric age group. Evidence is against prescribing these medications to the elderly. A list of such medications is called Beers criteria, which was revised by the American Geriatrics Society in 2015. AIMS: Using the Beer's list as reference, the researchers intend to find the extent and prevalence of potentially inappropriate medication (PIM) in geriatric population residing in different settings. SETTINGS AND DESIGN: The researchers analyzed prescription pattern of 200 individuals with age ≥65 years, 100 individuals from old-age homes (OAHs) and 100 individuals from a tertiary care hospital. After collecting data, the researchers tallied each prescription with list of drugs in Beers criteria to find all the possible PIMs in both the groups. RESULTS: It was found that the average age of residents of OAHs was significantly higher (P < 0.002) than the corresponding group from a tertiary care hospital. The residents of OAHs were also a receiving significantly higher (P < 0.0001) number of PIM than their counterparts from the tertiary care hospital. The average number of PIMs prescribed to females in OAHs was also significantly higher than those in the other group. About 55% of residents of OAHs received at least one PIM, compared to just 26% in the other group. At least 27% of individuals of OAHs received two or more PIMs, compared to just 2% in a tertiary care hospital. Lorazepam was the most commonly prescribed PIM in OAHs, whereas ranitidine was the most common PIM in a tertiary care hospital. Ibuprofen was the second most common PIM, with 15% of OAHs residents receiving this drug, while none of the patients from a tertiary care hospital received ibuprofen. CONCLUSION: All the results point toward a poor prescription pattern in the residents of OAHs compared to those receiving care from a tertiary care hospital.

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INTRODUCTION: A strong association between posttraumatic stress disorder (PTSD) and problematic alcohol use has been demonstrated among Veteran populations exposed to combat trauma. Several traits, such as higher levels of risk-taking propensity (RTP) and impulsivity (e.g., negative urgency [NU]), are associated with both increased PTSD symptom-atology and greater alcohol use problems. METHODS: The present study examined the effects of NU and RTP on alcohol use (measured by average weekly alcohol consumption and number of binge drinking days in 1 month), as well as their potential moderating effects on the association between PTSD symptom severity and alcohol use in a sample of Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) US Veterans. We hypothesized that NU and RTP would both significantly predict alcohol use and moderate the relation between PTSD symptom severity and alcohol use, such that the association between PTSD symptoms and alcohol use would be greater among individuals high compared to low in NU and RTP. RESULTS: As hypothesized, the main effects of RTP and NU were significantly positively associated with average weekly alcohol consumption and the number of binge drinking days in the past month. However, neither NU nor RTP moderated the relation between PTSD and either alcohol variable. DISCUSSION: NU and RTP may represent transdiagnostic risk markers for PTSD and alcohol use problems; however, the current study did not support an exploratory role of NU or RTP in the association between PTSD and alcohol use phenotypes.

INTRODUCTION: On constate une forte association entre le trouble de stress post-traumatique (TSPT) et la consommation problématique d'alcool dans les populations de vétérans exposés au combat. Plusieurs caractéristiques, telles qu'une plus grande propension à prendre des risques (PPR) et l'impulsivité (p. ex., l'urgence négative [UN]), sont liées à la fois à l'augmentation des symptômes de TSPT et à de plus grands problèmes de consommation d'alcool. MÉTHODOLOGIE: La présente étude a évalué les effets de l'UN et de la PPR sur la consommation d'alcool (mesurés d'après la moyenne hebdomadaire de consommation d'alcool et le nombre de journées de beuverie en un mois) de même que leurs effets modérateurs potentiels sur l'association entre la gravité des symptômes de TSPT et la consommation d'alcool dans un échantillon de vétérans américains de l'Opération Liberté immuable, de l'Opération Liberté irakienne et de l'Opération Aube nouvelle. Les chercheurs ont postulé que l'UN et la PPR seraient à la fois d'importants prédicteurs de la consommation d'alcool et un modérateur de la relation entre la gravité des symptômes de TSPT et la consommation d'alcool. Ainsi, l'association entre les symptômes de TSPT et la consommation d'alcool serait plus marquée chez les personnes ayant une UN et une PPR importantes que chez celles qui ayant de légers comportements de ce type. RÉSULTATS: Comme on l'a postulé, les principaux effets de la PPR et de l'UN avaient une corrélation positive significative avec la consommation hebdomadaire d'alcool et le nombre de journées de beuverie au cours du mois précédent. Cependant, ni l'UN ni la PPR ne modéraient la relation entre le TSPT et ces deux variables liées à l'alcool. DISCUSSION: L'UN et la PPR peuvent être des marqueurs de risque transdiagnostiques de TSPT et de problèmes de consommation d'alcool. Cependant, cette étude ne soutenait pas le rôle exploratoire de l'UN ou de la PPR dans l'association entre le TSPT et les phénotypes de consommation d'alcool.