RESUMEN

The use of manganese bacteriopheophorbide characterized by a high relaxation capacity and selectively accumulating in the tumor as a contrast agent for magnetic resonance tomography significantly improves tumor contrasting against the background of normal tissues. The pharmacokinetics and selectivity of accumulation were studied by diffuse reflection spectroscopy.

Asunto(s)

Bacterioclorofilas/química , Medios de Contraste/química , Imagen por Resonancia Magnética/métodos , Compuestos de Manganeso/química , Animales , Bacterioclorofilas/farmacocinética , Carcinoma de Ehrlich/diagnóstico por imagen , Carcinoma de Ehrlich/metabolismo , Carcinoma de Ehrlich/patología , Medios de Contraste/farmacocinética , Compuestos de Manganeso/farmacocinética , Ratones , Ratones Desnudos , Cintigrafía