RESUMEN
108 patients with atherosclerosis of aorto-iliac segment have undergone various reconstructive operations on this segment. Depending on the treatment all the patients were divided in 2 groups (test group--54 patients, control group--54 patients). The patients of the control group received aspirin, rheopolyglucin and trental for correction of hemorheology and hemocoagulation disorders. In patients of the test group at the same time as this treatment, the indirect electrochemical blood oxidation by intravenous infusion of 0.03% sodium hypochlorite was applied. Regional hemodynamics, hemorheology and hemostasis indices were studied in all the patients. It was established that indirect electrochemical blood oxidation permits to significantly improve the hemorheology indices, to diminish thrombophilia phenomenon during the treatment and early postoperative period. It was noted that early thrombotic reocclusion and amputations rates were reduced in the test group.
Asunto(s)
Anticoagulantes/administración & dosificación , Aorta Abdominal , Enfermedades de la Aorta/cirugía , Arteriopatías Oclusivas/cirugía , Arteria Ilíaca , Oxidantes/administración & dosificación , Inhibidores de Agregación Plaquetaria/administración & dosificación , Complicaciones Posoperatorias/prevención & control , Hipoclorito de Sodio/administración & dosificación , Trombosis/prevención & control , Adulto , Anciano , Arteriopatías Oclusivas/sangre , Arteriopatías Oclusivas/fisiopatología , Aspirina/administración & dosificación , Dextranos/administración & dosificación , Electroquímica , Hemodinámica , Hemorreología , Humanos , Infusiones Intravenosas , Inyecciones Intravenosas , Persona de Mediana Edad , Oxidación-Reducción , Pentoxifilina/administración & dosificaciónAsunto(s)
Alérgenos/efectos adversos , Nativos de Hawái y Otras Islas del Pacífico , Vías Férreas , Adolescente , Adulto , Niño , Humanos , Hipersensibilidad/epidemiología , Hipersensibilidad/etiología , Persona de Mediana Edad , Nativos de Hawái y Otras Islas del Pacífico/estadística & datos numéricos , Prevalencia , Grupos Raciales , Siberia/epidemiologíaRESUMEN
The article provides a description of a new statistical information supply of a polyclinic based on a special registration form--"An ambulatory patient coupon". The peculiarities and advantages of this document are demonstrated, some findings are provided.
Asunto(s)
Instituciones de Atención Ambulatoria/organización & administración , Registros Médicos , Humanos , U.R.S.S.RESUMEN
A change was found in the correlation between donor and acceptor adsorptive sites on the collagen surface in NaCl solution treatment. The number of binding sites was estimated by the value of spin-spin interaction constant (alpha) of native and treated by 3% NaCl solution; it accounts for 12,5 sites per 100 amino acid residues. A non-specific effect of water freezing after Na+ and K+ ions penetration was noticed.
Asunto(s)
Colágeno/metabolismo , Sodio/metabolismo , Animales , Sitios de Unión , Bovinos , Humanos , Cinética , Potasio/metabolismo , Unión Proteica , Ratas , Cloruro de Sodio , TermodinámicaRESUMEN
The state of water protons and peptide chains in natural collagen was investigated by the method of nuclear magnetic resonance. The study of orientation and temperature dependence of collagen PMR spectra allows us to mage a conclusion about the considerable disorder of mutual orientation in the polypeptide chains at the temperature above -4 degrees C. Under these conditions it was observed that natural collagen was near to the liquid-crystal. The phasic transition at -4 degrees C was discovered, the latter was followed by an abrupt change of the character of water proton mobility and by the change of orientation of collagen fibres order. The thermal effect of transition was measured, the latter presents 18k/gr of the whole specimen.