RESUMEN
BACKGROUND: An Asthma Adherence Pathway (AAP) application, which is an Internet application that combines patient and clinician education strategies to promote adherence to asthma therapy, has been developed. OBJECTIVE: The primary objective of this pilot study was to evaluate the effectiveness of the AAP application with electronic adherence monitors on asthma control. Secondary objectives evaluated the effect of AAP and monitors on medication adherence, asthma symptoms, quality of life, psychosocial factors, and barriers to treatment. METHODS: Adult patients with asthma were randomly assigned either to intervention (n = 19) or control (n = 20) groups in this 3-month prospective study, and they completed the Asthma Control Questionnaire (ACQ). Intervention patients completed the AAP software and were given barrier-specific motivational interviewing adherence strategies and a SmartTrack device to monitor mometasone furoate/formoterol (MF/F) use. Clinicians in the interventional group received adherence management training. Interventional patients were given feedback regarding adherence findings at each visit. Treatment adherence was determined by the mean of 4 measures of doses taken over 3 months. Control patients were not monitored for MF/F adherence. RESULTS: The mean MF/F adherence in the intervention group was 81%. The intervention and control groups did not differ on the mean baseline ACQ. Thirteen intervention patients achieved the minimal important difference (defined as an improvement ≥0.5 units on the ACQ) compared with 6 control patients (P = .016). The intervention group showed greater improvement in the ACQ (0.75) than the control group (0.19) representing a moderate-to-large effect size of d = 0.638. CONCLUSIONS: The AAP was effective in promoting adherence and helped to improve asthma control. These findings provide preliminary validation of the AAP model.
Asunto(s)
Albuterol/uso terapéutico , Asma/tratamiento farmacológico , Broncodilatadores/uso terapéutico , Intervención basada en la Internet , Cumplimiento de la Medicación , Combinación Furoato de Mometasona y Fumarato de Formoterol/uso terapéutico , Entrevista Motivacional/métodos , Educación del Paciente como Asunto/métodos , Adulto , Anciano , Alergólogos/educación , Asma/fisiopatología , Educación a Distancia , Equipos y Suministros , Femenino , Humanos , Masculino , Persona de Mediana Edad , Proyectos Piloto , Neumólogos/educación , Adulto JovenRESUMEN
In the United States, venous thromboembolism is associated with high mortality and morbidity affecting as many as 900 000 people (1-2 per 1000) each year. Estimates suggest that 60 000 to 100 000 Americans die of deep venous thrombosis/pulmonary embolism and 10% to 30% die within 1 month of diagnosis, with sudden death being the first symptom in approximately 25% of population with pulmonary embolism. One-half of the patients with deep venous thrombosis will have postthrombotic syndrome, which includes swelling, pain, discoloration, and scaling in the affected limb. Approximately 33% of patients will have a recurrence within 10 years. It is important to understand the anatomy of the pulmonary circulation and the pathophysiology of the disease as it leads to understanding of the potential devastating clinical consequences.
Asunto(s)
Pulmón/anatomía & histología , Pulmón/fisiología , Circulación Pulmonar/fisiología , Tromboembolia Venosa/fisiopatología , Humanos , Morbilidad , Embolia Pulmonar/mortalidad , Factores de Riesgo , Estados Unidos , Tromboembolia Venosa/epidemiología , Tromboembolia Venosa/mortalidad , Trombosis de la Vena/mortalidadRESUMEN
Venous thromboembolisms are major risk factors for many of our hospitalized patients. These events, however, can be prevented with prophylactic measurements when administered appropriately and on a timely basis. As patients are admitted, discharged, transferred, and scheduled for procedures on an hourly basis, anticoagulation and deep vein thrombosis prophylaxis are held or discontinued in anticipation for possible procedures. This results in delay of care and intervals where patients may not be covered with any prophylactic measurements. Similarly, alterations in clinical status can quickly change such as an increase in creatinine levels or the development of a new bleed, thus requiring a revision in their deep vein thrombosis prophylaxis. Nurses, therefore, play an integral role in not only administering the medicine but also routinely assessing the patients' clinical status and, therefore, their deep vein thrombosis prophylactic regimens as well. This article will review the indications, scoring systems, common prophylactic methods, and special populations at increased risks for venous thromboembolisms.
Asunto(s)
Anticoagulantes/uso terapéutico , Embolia Pulmonar/tratamiento farmacológico , Tromboembolia Venosa/tratamiento farmacológico , Tromboembolia Venosa/fisiopatología , Trombosis de la Vena/tratamiento farmacológico , Humanos , Aparatos de Compresión Neumática Intermitente , Neoplasias , Evaluación en Enfermería , Factores de Riesgo , Medias de CompresiónRESUMEN
Advanced therapies are available for both deep venous thrombosis and pulmonary embolism when anticoagulation alone is not sufficient to improve clinical outcomes. In some cases, clinical deterioration ensues despite anticoagulation, and this requires unique techniques that can ameliorate the clinical course. Such advancements are described in this upcoming article.
Asunto(s)
Catéteres , Terapia Trombolítica/métodos , Tromboembolia Venosa/epidemiología , Tromboembolia Venosa/fisiopatología , Tromboembolia Venosa/terapia , Anticoagulantes/uso terapéutico , Hospitalización , Humanos , Embolia Pulmonar/terapia , Trombosis de la VenaRESUMEN
Respiratory failure is a condition in which the respiratory system fails in one or both of its gas exchange functions. It is a major cause of morbidity and mortality in patients admitted to intensive care units. It is a result of either lung failure, resulting in hypoxemia, or pump failure, resulting in alveolar hypoventilation and hypercapnia. This article covers the basic lung anatomy, pathophysiology, and classification of respiratory failure.
Asunto(s)
Insuficiencia Respiratoria/clasificación , Insuficiencia Respiratoria/fisiopatología , Cuidados Críticos , Humanos , Hipercapnia/complicaciones , Hipoxia/complicaciones , Unidades de Cuidados Intensivos , Insuficiencia Respiratoria/etiología , Fenómenos Fisiológicos RespiratoriosRESUMEN
The management of acute respiratory failure varies according to the etiology. A clear understanding of physiology of respiration and pathophysiological mechanisms of respiratory failure is mandatory for managing these patients. The extent of abnormality in arterial blood gas values is a result of the balance between the severity of disease and the degree of compensation by cardiopulmonary system. Normal blood gases do not mean that there is an absence of disease because the homeostatic system can compensate. However, an abnormal arterial blood gas value reflects uncompensated disease that might be life threatening.