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Aim and objective: To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex). Materials and methods: This study included 64 primary molars with irreversible pulpitis indicated for single visit pulpectomy. After obtaining informed consent from the parents, all the teeth were randomly allocated to one of four groups. Pulpectomy was performed using rubber dam isolation and was obturated. The samples were categorized into the four groups based on obturation material namely, group A: curcumin with calcium hydroxide in equal proportions, group B: curcumin, group C: calcium hydroxide, and group D: Metapex. Clinical and radiographic outcomes were evaluated at time intervals of 10 days, 1 month, 3 months, and 6 months. Data was subjected to statistical analysis. Chi-square tests were used compare the groups. Results: At the end of 6 months, clinical and radiographic success rates of groups A, B, and C showed 81.3%, 61.5%, and 93.8%, respectively, while group D had 100% success rate. Conclusion: Among the four groups, the hierarchy of success rates are as follows: Metapex > calcium hydroxide > curcumin and calcium hydroxide > curcumin. However, various formulations and combinations of curcumin can still be extended with larger sample size. Clinical significance: Curcumin and calcium hydroxide paste can be used as an obturating material with further follow-up studies. How to cite this article: Bommareddy CS, Ramkumar H, Dakshinamurthy S, et al. Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15(S-1):S35-S39.
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INTRODUCTION: "Lesion sterilization and tissue repair" (LSTR) is a non-instrumentation endodontic treatment modality that has recently gained popularity with promising results in several clinical trials. However, there is a dearth of evidence regarding the concentration of modified triple antibiotic paste (MTAP) to be used for the procedure. AIM AND OBJECTIVE: To compare the clinical and radiographic efficacy of 1 mg/mL and 1 g/mL concentrations of MTAP (ciprofloxacin, metronidazole, and clindamycin) used in LSTR of primary molars. MATERIALS AND METHODS: Sixty-four infected primary molars in children between 4 years and 10 years of age were randomly allocated to two groups. Lesion sterilization and tissue repair at 1 mg/mL concentration of MTAP (group I) and 1 g/mL concentration of MTAP (group II) was performed. Clinical and radiographic outcomes were evaluated using Coll and Sadrian's criteria at 10 days, 1 month, and 3 months and the results were tabulated. STATISTICAL ANALYSIS: The data obtained were subjected to statistical analysis with IBM. SPSS statistics software 23.0 Version. To test the significance in categorical data, a Chi-square test was used. The probability value of 0.05 was considered significant. RESULTS: At the end of 3 months review, clinical success rates of group I and group II were 84.4 and 90.6%, respectively, and radiographic evaluation showed group I-78.1% and group II-90.6%. CONCLUSION: Both 1 mg/mL and 1 g/mL concentrations of MTAP used in LSTR of primary molars had similar success rates with no statistically significant difference. CLINICAL SIGNIFICANCE: Lesion sterilization and tissue repair when found to be equally effective in less concentration may aid in achieving adequate infection control with the least detrimental effect on the remaining vital pulp and periradicular structures. In addition, this circumvents the systemic administration of potent antibiotics thus combating antibiotic resistance. HOW TO CITE THIS ARTICLE: Shankar K, Ramkumar H, Dhakshinamoorthy S, et al. Comparison of Modified Triple Antibiotic Paste in Two Concentrations for Lesion Sterilization and Tissue Repair in Primary Molars: An In Vivo Interventional Randomized Clinical Trial. Int J Clin Pediatr Dent 2021;14(3):388-392.