RESUMEN
OBJECTIVES: To evaluate the use of a double balloon catheter in the termination of pregnancy with fetal death in the second and third trimesters, in comparison with the administration of extra-amniotic PGF2-alpha. METHODS: Twenty cases with IUFD at > 20 weeks of gestation were divided into two groups. Group I was subjected to the double balloon alone, while in Group II extra-amniotic instillation of PGF2-alpha via a Foley's catheter was used. RESULTS: There were no significant differences between the two groups with regard to induction-expulsion time, induction-delivery time and failure rate. CONCLUSIONS: The double balloon catheter proved to be an effective non-pharmacological method. The technique was simple and well tolerated by the patients. The side-effects of the prostaglandin and the cost of the medication were avoided.
Asunto(s)
Aborto Inducido/métodos , Cateterismo , Dinoprost/uso terapéutico , Muerte Fetal , Adulto , Femenino , Humanos , Embarazo , Segundo Trimestre del Embarazo , Tercer Trimestre del EmbarazoRESUMEN
Induction of labor was performed in 20 pregnant females with postmaturity (greater than 294 days) using either oral PGE2 tablets (0.5 mg) or i.v. oxytocin drip (each group n = 10). The induction-establishment interval was significantly shorter in the oxytocin group (P less than 0.005). Moreover, the uterine activity (in Alexandria units) at 3 h post-induction and at the end of the first stage of labor, was significantly higher with i.v. oxytocin (P less than 0.005). However, the induction-delivery interval did not differ in both groups. All cases delivered spontaneously with a satisfactory Apgar score.
Asunto(s)
Dinoprostona/administración & dosificación , Trabajo de Parto Inducido/métodos , Embarazo Prolongado/efectos de los fármacos , Administración Oral , Adulto , Dinoprostona/efectos adversos , Femenino , Monitoreo Fetal , Frecuencia Cardíaca Fetal/efectos de los fármacos , Humanos , Infusiones Intravenosas , Oxitocina/administración & dosificación , Oxitocina/efectos adversos , Embarazo , Contracción Uterina/efectos de los fármacosRESUMEN
Pilot studies showed that, i.v. infusions of the renal prostaglandin A1 (PGA1) induced a triad of beneficial clinical responses in severe pre-eclampsia; the blood pressure became normotensive, renal function was markedly improved and labour was successfully induced. The present study was an attempt to develop a therapeutic schedule of PGA1 administration in severe toxemia. Twenty one cases of severe pre-eclampsia (in 3 equal groups) received i.v. infusions of PGA1 in a dose range of 0.1-0.5 microgram/kgm/min for 12 - 24 hours and the B.P., uterine activity and FHR were continuously monitored during and for 12 hours following the infusion period. The 0.1 microgram/Kgm/min dose for 12 hours was inadequate while 0.5 microgram/Kgm/min for 12 hours induced a good hypotensive response and the cases delivered within 48 hours but a post-infusion rebound in hypertension was observed. The dose of 0.5 microgram/Kgm/min for 24 hours appeared to be optimal in clinical terms since a satisfactory effect on B.P. was recorded and all the subjects delivered normal babies during the infusion period with minimal or no post-infusion rebound rise in B.P. This approach holds a major potential in the treatment of severe pre-eclampsia.