RESUMEN
BACKGROUND/AIMS: It was speculated that there was a relationship between the intensity of tissue eosinophilic infiltration in colonic malignancies and their prognosis. This retrospective study aimed to investigate the frequency and intensity of tissue eosinophilia in various colonic neoplasms, including serrated adenomas. METHODS: We evaluated 448 colonic neoplasms to determine eosinophilic infiltration: 96 hyperplastic polyps, 50 serrated adenomas, 19 flat adenomas, 154 tubular adenomas, 71 tubulovillous adenomas, 13 villous adenomas and 45 adenocarcinomas. The eosinophilic infiltration was categorized into three groups by evaluating the percentage of eosinophils relative to total stromal inflammatory cells: mild (0-5%), moderate (5-40%), and marked (>;40%). Chi-square and Fisher's exact tests were used for analyses. P value <0.05 was considered statistically significant. RESULTS: Moderate (46.7%) and marked (52.9%) intensity were noted in all colonic adenomas. Most of the hyperplastic polyps (96%) and adenocarcinomas (75.6%) showed mild intensity. Mostly moderate eosinophilic infiltration was observed in serrated adenomas. CONCLUSIONS: Our findings suggest that the intensity of tissue eosinophilia is most prominent in adenomas including serrated adenomas and is diminished from adenoma to carcinoma. This finding may be used as a diagnostic indicator.
Asunto(s)
Neoplasias del Colon/patología , Eosinofilia/patología , Distribución de Chi-Cuadrado , Humanos , Estudios Retrospectivos , Índice de Severidad de la EnfermedadRESUMEN
The lateral meniscus tends to have more developmental variation than the medial counterpart. This is a report of an accessory discoid layer of lateral meniscus. All arthroscopic, magnetic resonance imaging and histopathological views are presented.