RESUMEN
Among the collection strains of S. flexneri 10.5; 5.5; 2.6; 2.6 and 7.9% of strains were resistant to ampicillin, tetracycline, ceftryaxon, cefasoline, chloramphenycol, respectively. The maximum number of R-determinants of one strain was 4. The strains resistant to cefalosporynes were not revealed; among newly isolated strains of this agent, these strains resistant to ampicilline, tetracycline and chloramphenycol made 20%. Among the collection and newly isolated strains of S. flexneri, isolated 50 and more years ago, the part of colicinogenic ones was 10%. And, on the contrary both for the collection and newly isolated strains of S. sonnei colicinogenic activity is specific biological property (above 80%). Correlation relation between two tested pathogenic factors, certain serovars and biovars of the agents, was not revealed.
Asunto(s)
Antibacterianos/farmacología , Colicinas/biosíntesis , Farmacorresistencia Bacteriana/efectos de los fármacos , Shigella flexneri/efectos de los fármacos , Shigella sonnei/efectos de los fármacos , Escherichia coli K12/metabolismo , Shigella flexneri/aislamiento & purificación , Shigella flexneri/metabolismo , Shigella sonnei/aislamiento & purificación , Shigella sonnei/metabolismoAsunto(s)
Especificidad de Anticuerpos , Sueros Inmunes/farmacología , Mucosa Intestinal/inmunología , Animales , Relación Dosis-Respuesta Inmunológica , Epitelio/efectos de los fármacos , Epitelio/inmunología , Epitelio/ultraestructura , Inmunización , Mucosa Intestinal/efectos de los fármacos , Mucosa Intestinal/ultraestructura , Ratones , Microscopía Electrónica , ConejosRESUMEN
The present study has revealed that persons working at offal and bone processing plants show no specific pathology, peculiar to such plants, in the state of their health and severe mass diseases among these persons are absent. Nevertheless, rather frequent occurrence of erysipeloid should be noted. The survey of workers employed at different stages of the production process has revealed the presence of ornithosis, listeriosis and leptospirosis infections. No clinically manifest cases of these diseases have been detected. The infection of individual workers occurs in the process of production as the result of contacts with infected raw materials of animal origin. For preventing the possible spread of infection great attention should be paid to sanitary, hygienic and epidemiological measures.