RESUMEN
In this case report the authors describe histomorphological findings of acute lung injury with laboratory-confirmed influenza type A(H1N1) pneumonia leading to the death of a 30 year-old unvaccinated man after 27 days of hospitalisation. Histologically all three types of acute lung injuries were unusually present (diffuse alveolar damage, acute interstitial pneumonia, organizing pneumonia) in different phases of resorption and reparation with transition to extensive fibrosis.
Asunto(s)
Lesión Pulmonar Aguda , Subtipo H1N1 del Virus de la Influenza A , Gripe Humana , Neumonía , Fibrosis Pulmonar , Lesión Pulmonar Aguda/complicaciones , Adulto , Humanos , Gripe Humana/complicaciones , Pulmón , Masculino , Neumonía/complicaciones , Fibrosis Pulmonar/complicacionesRESUMEN
The trend during the past years is to prefer natural drugs to synthetically prepared medicines. Due to its important antiphlogistic, antiseptic and antihidrotic effects, Salvia officinalis L. has a wide use in medicine, pharmacy and cosmetics in various dosage forms. The aim of this research was the formulation of Salvia officinalis L. in the form of a tincture to hydrogels. Gels were parallelly prepared on the basis of the natural polymer chitosan and the synthetic polymer Carbopol 940. The evaluation was focused on the influence of the anionic polymer and the cationic polymer in different concentrations on hydrogel flow properties. Glycerol functioning as a humectant was used in various percentage ratios. On the basis of the determination of rheological parameters and flow curves lapses the most suitable hydrogel from the application point of view was selected.
Asunto(s)
Fitoterapia , Preparaciones de Plantas , Salvia officinalis , Química Farmacéutica , Humanos , HidrogelesRESUMEN
The authors evaluated surveillance of acute respiratory infections (ARI), influenza and influenza-like illnesses (ILI) in the Slovak Republic (SR). They analyze morbidity, age-specific morbidity, complications, mortality, number of influenza viruses isolations and vaccination coverage rates in the SR in the years 1993-2008. They focus mainly on the analysis during the epidemic. Most epidemics have been caused by influenza virus A subtype H3N2. The age group mostly affected by morbidity during the year were children at the age of 0-5, while during the epidemic, the highest morbidity was recorded among school children at the age of 6-14. A complicated clinical course of the disease was reported in 1,422,836 patients (5.1%). Since the 2002/2003 influenza season, the sentinel physicians have participated in taking biological material, which ensures monitoring of influenza viruses circulating in the SR. As of the 2006/2007 season, the ARI/ILI have been reported separately in the SR in accordance with the monitoring requirements set by the European Influenza Surveillance Scheme (EISS) project, and the calculation of morbidity is done from the number of persons, who are in care of the reporting physicians: Vaccination coverage in SR is still very low in comparison with other European Union (EU) countries.
Asunto(s)
Vigilancia de la Población , Infecciones del Sistema Respiratorio/epidemiología , Enfermedad Aguda , Adolescente , Adulto , Distribución por Edad , Niño , Preescolar , Epidemias , Femenino , Humanos , Lactante , Recién Nacido , Vacunas contra la Influenza/administración & dosificación , Gripe Humana/complicaciones , Gripe Humana/epidemiología , Masculino , Persona de Mediana Edad , Morbilidad , Infecciones del Sistema Respiratorio/complicaciones , Infecciones del Sistema Respiratorio/virología , Eslovaquia/epidemiología , Adulto JovenRESUMEN
Influenza illnesses and positive laboratory tests for the presence of influenza virus in recent years in the districts of Kosice I-IV and surroundings have only occurred during the winter season. In May to July 2010 only one positive laboratory test for the presence of influenza virus A/H1N1-2009 was reported. In 2011, during the same period, a total of 29 positive laboratory tests recorded the presence of influenza virus A/ H1N1-2009 in individuals with typical clinical symptoms of influenza. Of 29 clinical cases, 27 were diagnosed as influenza and 2 as SARI; 4 cases involved children.