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J Expo Sci Environ Epidemiol ; 25(3): 317-23, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25352161

RESUMEN

As personal care products (PCPs) are used in close contact with a person, they are a major source of consumer exposure to chemical substances contained in these products. The estimation of realistic consumer exposure to substances in PCPs is currently hampered by the lack of appropriate data and methods. To estimate aggregate exposure of consumers to substances contained in PCPs, a person-oriented consumer exposure model has been developed (the Probabilistic Aggregate Consumer Exposure Model, PACEM). The model simulates daily exposure in a population based on product use data collected from a survey among the Dutch population. The model is validated by comparing diethyl phthalate (DEP) dose estimates to dose estimates based on biomonitoring data. It was found that the model's estimates compared well with the estimates based on biomonitoring data. This suggests that the person-oriented PACEM model is a practical tool for assessing realistic aggregate exposures to substances in PCPs. In the future, PACEM will be extended with use pattern data on other product groups. This will allow for assessing aggregate exposure to substances in consumer products across different product groups.


Asunto(s)
Cosméticos/química , Exposición a Riesgos Ambientales/análisis , Contaminantes Ambientales/análisis , Modelos Estadísticos , Ácidos Ftálicos/análisis , Monitoreo del Ambiente , Humanos , Países Bajos , Medición de Riesgo/métodos
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