RESUMEN
A male infant born at 23 weeks gestation with a birthweight of 660 grams presented with retinopathy of prematurity (ROP) that began progressing at 44 weeks. He subsequently developed Zone III, Stage 3, pre-plus disease in both eyes (OU), as well as scattered exudates in the macula, dragged vessels temporally, and an exudative retinal detachment temporally in the left eye after a period of regressing and stable ROP. After bilateral laser photocoagulation, there was regression of the neovascularization, resolution of the exudative detachment, and eventual stabilization of disease OU by 12 months postmenstrual age. [Ophthalmic Surg Lasers Imaging Retina. 2021;52:403-406.].
Asunto(s)
Desprendimiento de Retina , Retinopatía de la Prematuridad , Edad Gestacional , Humanos , Lactante , Recién Nacido de Bajo Peso , Recién Nacido , Coagulación con Láser , Masculino , Desprendimiento de Retina/diagnóstico , Desprendimiento de Retina/etiología , Desprendimiento de Retina/cirugía , Retinopatía de la Prematuridad/complicaciones , Retinopatía de la Prematuridad/diagnóstico , Retinopatía de la Prematuridad/cirugíaAsunto(s)
Hiperhomocisteinemia/complicaciones , Órbita/irrigación sanguínea , Trombosis de la Vena/etiología , Femenino , Humanos , Angiografía por Resonancia Magnética , Persona de Mediana Edad , Órbita/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Trombosis de la Vena/diagnósticoRESUMEN
Basal cell carcinoma accounts for 90% of malignant tumors of the eyelid. Basal cell carcinoma has been reported to rarely occur in conjunction with osteoma cutis or bone formation in the skin. The mechanism of this secondary osteoma cutis has yet to be explained. Herein, the authors present the case of a 68-year-old woman with a rapidly enlarging basal cell carcinoma with secondary osteoma cutis of the left lower eyelid.
Asunto(s)
Carcinoma Basocelular , Osteoma , Neoplasias Cutáneas , Anciano , Párpados , Femenino , Humanos , OsteogénesisRESUMEN
Calcifying nested stromal-epithelial tumor (CNSET) is a rare neoplasm. In the 31 reported cases, CNSET is predominantly found in young girls and women. Beckwith-Wiedemann syndrome (BWS) (OMIM #130650) is an overgrowth syndrome with an increased risk to develop cancer. Associations have been seen between BWS and embryonal tumors, especially Wilms tumor, hepatoblastoma, and adrenocortical carcinoma. Here we report on a female patient with BWS who presented with CNSET. Two other cases with the same association have been reported, with our case representing the third such reported in the literature. Although we recognize a potential reporting bias we speculate that CNSET may represent an unrecognized addition to the spectrum of BWS tumorigenesis.
Asunto(s)
Síndrome de Beckwith-Wiedemann/genética , Metilación de ADN/genética , Neoplasias Hepáticas/genética , Hígado/patología , Adolescente , Síndrome de Beckwith-Wiedemann/patología , Femenino , Impresión Genómica , Humanos , Neoplasias Hepáticas/patología , Células del Estroma/patología , Tumor de Wilms/genética , Tumor de Wilms/patologíaRESUMEN
This is a case of a newborn female with congenital pancreatic cysts discovered incidentally. The 5-week-old infant had multiple abdominal cysts originating from the pancreas. When the radiologist catheter placement failed to alleviate the symptoms, the infant underwent laparoscopic excision. The lesion, however, recurred 11 months after the first excision, leading to a second surgical procedure including excision and marsupialization. A review of the literature revealed that this is a rare condition. Herein, we discuss the characteristics of the case, including medical imaging, drainage catheter placement, surgical treatment, pathological findings, and follow-up. Differential diagnoses, clinical presentations, treatment options, and patient outcomes are also discussed. Although rare, congenital pancreatic cyst should be considered in the differential diagnosis of an infant with cystic lesion of the pancreas.
Asunto(s)
Quiste Pancreático/congénito , Quiste Pancreático/patología , Femenino , Humanos , Lactante , Quiste Pancreático/cirugía , RecurrenciaRESUMEN
Pediatric cardiac tumors are extremely rare and usually benign. We selected four unique cases of pediatric cardiac tumors from a 15-year period at our institution. The four chosen cases represent unique, rare primary tumors of the heart. Our selection includes a case of Rosai Dorfman disease without systemic involvement, which is, to our knowledge, the second case of isolated cardiac Rosai Dorfman disease in a child. We present a case of subtotal replacement of myocardium by granulocytic sarcoma with minimal bone marrow involvement, representing the first reported case in a child manifested as hypertrophic cardiomyopathy, as well as a case of a primary synovial sarcoma arising from the atrioventricular (AV) node, representing the fourth reported pediatric case of a cardiac synovial sarcoma, and it is the first to arise from the AV node. Finally, we present a primary congenital infantile fibrosarcoma of the heart, which is, to our knowledge, the first confirmed cardiac congenital infantile fibrosarcoma. These four cases represent the need for continued inclusion of rare cardiac conditions in a clinician's differential diagnosis. Furthermore, they present the need for more in-depth molecular and genomic analysis of pediatric cardiac tumors in order to identify their etiopathogenesis.
Asunto(s)
Fibrosarcoma/patología , Neoplasias Cardíacas/patología , Histiocitosis Sinusal/patología , Leucemia Mieloide Aguda/patología , Miocardio/patología , Sarcoma Sinovial/patología , Adolescente , Biomarcadores de Tumor/análisis , Biopsia , Niño , Ecocardiografía , Resultado Fatal , Fibrosarcoma/química , Fibrosarcoma/genética , Fibrosarcoma/terapia , Neoplasias Cardíacas/química , Neoplasias Cardíacas/genética , Neoplasias Cardíacas/terapia , Histiocitosis Sinusal/metabolismo , Histiocitosis Sinusal/terapia , Humanos , Inmunohistoquímica , Lactante , Leucemia Mieloide Aguda/metabolismo , Leucemia Mieloide Aguda/terapia , Masculino , Miocardio/química , Sarcoma Sinovial/química , Sarcoma Sinovial/terapia , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
Calcifying nested stromal-epithelial tumor (CNSET), an extremely rare tumor found in the liver, was first described in 2001 by Ishak et al. The characteristic imaging features include large size, well-circumscribed, enhancing mass with calcification. To our knowledge, since 2001, there have been 29 reported. Typically arising from the right hepatic lobe, it is primarily found in children and shows clear predilection for females. Emphasizing imaging, we report a 14-year-old female with Beckwith-Wiedemann syndrome who presented with CNSET.