RESUMEN
Central hemodynamics and myocardial contractility have been studied during intermittent peritoneal dialysis (PD) in 46 patients with severe poisoning with organophosphorus insecticides (OPI). The volume of liquid, administered into the abdominal cavity for 30-40 min, was 1.5-2 1. During PD no considerable disturbances in the parameters under study have been observed irrespective of the baseline blood pressure level. That is why PD is recommended in patients with most severe forms of OPI poisonings accompanied by marked disturbances in hemo- and cardiodynamics.
Asunto(s)
Hemodinámica/fisiología , Insecticidas/envenenamiento , Compuestos Organofosforados , Diálisis Peritoneal , Función Ventricular Izquierda/fisiología , Humanos , Intoxicación/fisiopatología , Intoxicación/terapia , Sístole/fisiologíaRESUMEN
The results of central hemodynamic and myocardial contractility studies during hemodialysis in 62 patients with severe fluoroorganic insecticide poisoning complicated by exotoxic shock are reviewed. It has been established that hemodynamic disturbances are manifested in progressing fall of venous pressure, stroke volume and cardiac output accompanied by the onset of phase myocardial hypodynamia syndrome. The leading role of hypovolemia resulting from ultrafiltration in the pathogenesis of the above hemodynamic disturbances has been revealed. The results obtained make it possible to outline approaches aimed at correction of intraoperative hemodynamic disturbances and to increase safety of extracorporeal hemodialysis.