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1.
Scand J Surg ; 106(4): 325-331, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-28737103

RESUMEN

PURPOSE: We report 3- to 8-year follow-up results for the first tarsometatarsal joint derotational arthrodesis. METHODS: A total of 70 patients (88 feet) with symptomatic flexible hallux valgus were operated between 2003 and 2009. In all, 66 patients (94.3%) with 84 (95.5%) feet were enrolled in retrospective analysis; of those, 58 (87.9%) patients with 76 (90.5%) feet were followed for a mean of 5.1 (range: 3.0-8.3) years. Preoperative, 6 week postoperative, and late follow-up weightbearing radiographs were evaluated along with clinical examination and questionnaires. RESULTS: The mean hallux valgus angle improved 13.4° (95% confidence interval: 11.6-15.1, p < .001) at the latest follow-up, while the mean intermetatarsal angle correction was 4.5° (95% confidence interval: 3.7-5.2, p < .001). There were three (4.0%) nonunions, and seven (9.2%) feet needed reoperation during follow-up. CONCLUSION: First tarsometatarsal joint derotational arthrodesis is an effective procedure for correcting flexible hallux valgus deformity and provides a satisfactory long-term outcome.


Asunto(s)
Artrodesis/métodos , Hallux Valgus/cirugía , Huesos Metatarsianos/cirugía , Huesos Tarsianos/cirugía , Articulaciones Tarsianas/cirugía , Adulto , Anciano , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento
2.
Eur J Neurol ; 12(2): 86-92, 2005 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-15679695

RESUMEN

Severe head injury in early adulthood may increase the risk of dementia in older age, but it is not known whether head injury in later life also increases the risk of dementia. A representative sample (82%) of persons aged 70 years or older with a Mini-Mental State Examination (MMSE) test score of > or =26 (n = 325) were followed-up for 9 years to record all their fall-related head injuries resulting in traumatic brain injury (TBI). At the end of the follow-up period, 152 persons (81% of the surviving population) were examined for clinical dementia, according to DSM-IV criteria. Eight persons sustained a TBI and 34 developed dementia. Brain injury was associated with younger age at detection of dementia even when adjusted for sex and educational status (low educational status significantly associated with dementia); age-specific hazard ratio (95% confidence interval) 2.80 (1.35-5.81). In a population scoring > or =28 points in the baseline MMSE an apolipoprotein E (ApoE) epsilon4 phenotype was also associated with younger age at the time of detecting dementia; 3.56 (1.35-9.34), and the effect of brain injury and ApoE epsilon4 phenotype was synergistic; 7.68 (2.32-25.3). We conclude that fall-related TBI predicts earlier onset of dementia and the effect is especially high amongst subjects who carry the ApoE epsilon4 allele.


Asunto(s)
Accidentes por Caídas , Lesiones Encefálicas/complicaciones , Lesiones Encefálicas/epidemiología , Demencia/etiología , Factores de Edad , Anciano , Apolipoproteína E4 , Apolipoproteínas E/genética , Lesiones Encefálicas/genética , Demencia/genética , Femenino , Humanos , Masculino , Factores de Riesgo
3.
Eur J Neurol ; 10(2): 175-81, 2003 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-12603294

RESUMEN

A small proportion of patients with mild head injury (MHI) develop post-concussion symptoms (PCSs). We searched simple measures for the early detection of patients who are probable to develop PCSs. We recorded signs and symptoms, history of previous diseases, medications, and lifestyle factors and measured serum protein S-100B on admission in a series of 172 consecutive MHI patients admitted into the emergency room of a general hospital. A modified Rivermead Post-Concussion Symptoms Questionnaire was used to identify the patients with and without PCSs 1 month after the injury. We identified 37 patients with MHI who developed PCSs (22%). Odds ratios (OR) and 95% confidence intervals (CI) after adjustment for possible confounding variables were calculated by logistic regression. Independent early risk factors for PCSs in the MHI patients were skull fracture (OR 8.0, 95% CI 2.6-24.6), serum protein S-100B >/= 0.50 microg/l (OR 5.5, 95% CI 1.6-18.6), dizziness (OR 3.1, 95% CI 1.2-8.0), and headache (OR 2.6, 95% CI 1.0-6.5). Serum protein S-100B proved to be a specific, but not sensitive predictor of PCSs. The presence of skull fracture, elevated serum protein S-100B, dizziness, and headache may help the emergency room physician to identify patients at risk of PCSs and to refer them for further examination and follow-up.


Asunto(s)
Síndrome Posconmocional/diagnóstico , Adolescente , Adulto , Factores de Edad , Mareo/fisiopatología , Femenino , Escala de Coma de Glasgow , Cefalea/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Factores de Crecimiento Nervioso , Síndrome Posconmocional/sangre , Valor Predictivo de las Pruebas , Factores de Riesgo , Subunidad beta de la Proteína de Unión al Calcio S100 , Proteínas S100/sangre , Fracturas Craneales/fisiopatología
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