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1.
Eur J Ophthalmol ; 30(1): 175-180, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30644317

RESUMEN

AIM: To find out and compare various predictors of glaucoma-related visual impairments in primary and secondary glaucoma. METHODS: A prospective observational study of patients, who were above 30 years of age. They were diagnosed as primary/secondary glaucoma with visual acuity <20/200 Snellen's/visual field showing less than 20° isopter in at least one eye, with a minimum follow-up of one year at a tertiary center. Patients were classified into advanced and end-stage glaucoma and outcome was assessed according to visual acuity and visual fields to see predictors of visual impairments. RESULTS: There were 169 (99 primary/70 secondary) glaucoma patients with mean age of 62.67 ± 11.9 and 54.65 ± 15.26 years, respectively. Trauma (21.4%), complicated cataract surgery (15.7%), and silicon oil tamponade (14.3%) were common causes of secondary glaucoma. There was significant delay in diagnosis in primary compared to secondary glaucoma (57.57% vs 32.85%) and non-compliance was significantly higher in primary glaucoma (34.3% vs 17.1%, p = 0.01). In univariate analysis, literacy, income status, locality, and delayed or missed diagnosis were found to be significant (p < 0.05) according to visual acuity criteria. Out of the 33 patients who had undergone glaucoma filtration surgery, 18 (54.5%) were in the end-stage group. While 105 (77.2%) of 136 patients who were not subjected to any glaucoma filtration surgery reached end-stage glaucoma as per visual fields criteria (p = 0.011). CONCLUSION: Lack of awareness, delayed diagnosis, low literacy, and income were associated with poor visual outcome. Patients who underwent glaucoma filtration surgery had significantly better visual outcome in comparison to patients managed medically.


Asunto(s)
Glaucoma de Ángulo Cerrado/diagnóstico , Glaucoma de Ángulo Abierto/diagnóstico , Trastornos de la Visión/diagnóstico , Adulto , Anciano , Femenino , Cirugía Filtrante , Glaucoma de Ángulo Cerrado/fisiopatología , Glaucoma de Ángulo Cerrado/cirugía , Glaucoma de Ángulo Abierto/fisiopatología , Glaucoma de Ángulo Abierto/cirugía , Humanos , India , Presión Intraocular/fisiología , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Centros de Atención Terciaria , Trastornos de la Visión/fisiopatología , Trastornos de la Visión/cirugía , Agudeza Visual/fisiología , Campos Visuales/fisiología , Personas con Daño Visual
2.
Indian J Ophthalmol ; 67(6): 824-827, 2019 06.
Artículo en Inglés | MEDLINE | ID: mdl-31124495

RESUMEN

Purpose: To analyze the causes for late presentation in a series of patients with advanced retinopathy of prematurity (ROP) in a tertiary eye care institute in Eastern India. Methods: We analyzed our medical records and ROP database retrospectively from 2007 to 2015 and prospectively thereafter till 2017 to identify the factors for late presentation in babies with advanced ROP (stages 4 and 5). Results: A total of 71 eligible subjects were analyzed. The mean chronological age was 15.1 months (2 months to 14 years). The three important barriers were: (1) the system and neonatal care policy failure (n = 45; 63.3%), (2) parental negligence and ignorance (n = 19; 26.7%), and (3) ophthalmologist's misdiagnosis or unavailability (n = 7; 10%). Majority of the babies (63.3%) were admitted in the neonatal care unit when they were due for ROP screening with an average duration of stay of 35.5 days. Conclusion: The main barriers to early screening for ROP were related to availability of trained human resources, ignorance of "parents and health care personnel," and distance from the point of care. This calls for training of ophthalmologists, advocacy with neonatologists and parents, and create systems for better coordination and compliance of the care providers.


Asunto(s)
Atención a la Salud/organización & administración , Tamizaje Neonatal/métodos , Tiempo de Tratamiento/estadística & datos numéricos , Selección Visual/métodos , Adolescente , Niño , Preescolar , Femenino , Estudios de Seguimiento , Edad Gestacional , Humanos , Incidencia , India/epidemiología , Recién Nacido , Masculino , Pronóstico , Retinopatía de la Prematuridad/diagnóstico , Retinopatía de la Prematuridad/epidemiología , Estudios Retrospectivos , Factores de Riesgo
3.
Ophthalmic Surg Lasers Imaging Retina ; 49(7): 544-547, 2018 07 01.
Artículo en Inglés | MEDLINE | ID: mdl-30021044

RESUMEN

A prematurely born baby underwent lens-sparing vitrectomy for Stage 4B retinopathy of prematurity (ROP) in the left eye. This child had a stormy neonatal course, referred late, and was treated with intravitreal anti-vascular endothelial growth factor and laser in both eyes in the past. The surgery was uneventful, and the retina was attached until a month after surgery. Later, there was development of a break that led to the occurrence of rhegmatogenous retinal detachment in the operated eye. The retinal detachment increased with time during the course of 6 weeks. Surprisingly, the hole disappeared with spontaneous attachment of retina in the following weeks, with multiple depigmented spots over the posterior pole. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:544-547.].


Asunto(s)
Retina/fisiopatología , Desprendimiento de Retina/fisiopatología , Retinopatía de la Prematuridad/cirugía , Vitrectomía/efectos adversos , Femenino , Estudios de Seguimiento , Edad Gestacional , Humanos , Recien Nacido con Peso al Nacer Extremadamente Bajo , Recién Nacido de Bajo Peso , Recién Nacido , Recien Nacido Prematuro , Remisión Espontánea , Desprendimiento de Retina/etiología , Retinopatía de la Prematuridad/clasificación , Estudios Retrospectivos
4.
Br J Ophthalmol ; 102(9): 1232-1237, 2018 09.
Artículo en Inglés | MEDLINE | ID: mdl-29217515

RESUMEN

PURPOSE: To analyse the clinical characteristics and treatment outcomes of choroidal neovascular membranes (CNVM) in paediatric subjects at three paediatric retina referral centres. METHODS: Medical charts of patients aged 18 years or less with a diagnosis of CNVM were retrospectively reviewed. The demographic profile, laterality, presenting complaint, corrected vision, underlying pathology, fundus, fundus fluorescein angiogram and optical coherence tomogram (OCT) were analysed. CNVM type, frequency, treatment indications, recurrences and final visual acuity were noted. RESULTS: There were a total of 35 subjects (43 eyes) with a mean age of 11.2 years. The CNVMs were mostly type 2 (90.0%), classic (90.9%), subfoveal (59.09%) and active (84.1%). Best vitelliform macular dystrophy was found to be the most common association (32.5%). Intravitreal injection of an anti-vascular endothelial growth factor (VEGF) agent was the initial therapy of choice in all. Eyes with CNVMs responsive to anti-VEGF alone required a mean of 2.11 injections. Patients with recurrent disease (21.21%) had an average of 1.14 episodes per eye. While 50% of recurrent CNVMs stabilised with repeat anti-VEGF treatment, the remaining patients required photodynamic therapy, laser or surgery. CONCLUSION: Paediatric CNVMs in this series differed from those in the adult population with regard to aetiology, OCT and angiographic characteristics, treatment response and rate of recurrence.


Asunto(s)
Bevacizumab/administración & dosificación , Coroides/patología , Neovascularización Coroidal/diagnóstico , Fotoquimioterapia/métodos , Vasos Retinianos/patología , Adolescente , Inhibidores de la Angiogénesis/administración & dosificación , Neovascularización Coroidal/tratamiento farmacológico , Femenino , Angiografía con Fluoresceína/métodos , Estudios de Seguimiento , Fondo de Ojo , Humanos , Inyecciones Intravítreas , Masculino , Estudios Retrospectivos , Tomografía de Coherencia Óptica/métodos , Resultado del Tratamiento , Factor A de Crecimiento Endotelial Vascular/antagonistas & inhibidores , Agudeza Visual
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