RESUMEN
Intradermal nodular fasciitis is a rare but not extraordinary pathological finding with approximately 100 cases reported since originally described in 1990. Intradermal proliferative fasciitis, however, has only been reported twice and both arose in the postauricular region. Herein, we report a third case of intradermal proliferative fasciitis and the first to occur on the finger. This case was also unusual in its slow growth, and complete lack of smooth muscle actin expression that has only been reported once before.
Asunto(s)
Fascitis/patología , Dedos/patología , Femenino , Humanos , Persona de Mediana EdadAsunto(s)
Enfermedades Cutáneas Papuloescamosas/diagnóstico , Piel/patología , Treponema pallidum/aislamiento & purificación , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Cutáneas Papuloescamosas/patología , Serodiagnóstico de la Sífilis , Sífilis Cutánea/diagnósticoRESUMEN
Multiple clustered dermatofibromas describes a confluence of dermatofibromas in one anatomic location. We describe a 32-year-old man who presented for evaluation owing to skin papules and plaques and concerns about malignancy. Repeat histopathological evaluation found no evidence for dermatofibrosarcoma protuberans. Our case presents this relatively rare condition and discusses observation along with potential treatment options.
Asunto(s)
Histiocitoma Fibroso Benigno/patología , Neoplasias Cutáneas/patología , Adulto , Atrofia , Biopsia , Humanos , Masculino , Muslo/patologíaAsunto(s)
Granuloma Piogénico/patología , Enfermedades de la Piel/patología , Niño , Femenino , Humanos , RecurrenciaRESUMEN
Cutaneous metastases are infrequently encountered in dermatology. We describe a rare case of a urolethial carcinoma metastatic to the skin in an elderly female. The metastasis expanded rapidly and was thought to possibly be infectious on her initial evaluation by her primary team. We were called in as consultants and biopsied this mass to confirm our concern for metastatic disease. In this case there was an unknown primary tumor. Histologic staining patterns were used to suggest that the tumor may have originated from her urinary bladder.
Asunto(s)
Carcinoma de Células Transicionales/secundario , Neoplasias Primarias Desconocidas/patología , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/secundario , Anciano de 80 o más Años , Femenino , Humanos , Metástasis Linfática , Neoplasias Cutáneas/química , Negativa del Paciente al TratamientoRESUMEN
We present a case of a primary cutaneous carcinosarcoma (PCS). Histopathologically, PCS is defined as a biphasic tumor composed of malignant epithelial (carcinoma) and mesenchymal (sarcoma) elements. The diagnosis of PCS can be challenging, not only because of its rarity but also because superficial biopsies can result in sampling errors. Accurate diagnosis is essential, as PCS carries a higher recurrence and metastatic rate than epithelial carcinomas, thus requiring wider excision or Mohs micrographic surgery as well as closer clinical follow-up.
Asunto(s)
Carcinosarcoma/patología , Neoplasias de Cabeza y Cuello/patología , Cuero Cabelludo , Neoplasias Cutáneas/patología , Carcinosarcoma/cirugía , Neoplasias de Cabeza y Cuello/cirugía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cutáneas/cirugíaAsunto(s)
Cistoadenoma/diagnóstico , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Siringoma/diagnóstico , Adulto , Cistoadenoma/congénito , Cistoadenoma/patología , Femenino , Humanos , Neoplasias de las Glándulas Sudoríparas/congénito , Neoplasias de las Glándulas Sudoríparas/patología , Siringoma/congénito , Siringoma/patología , Muslo/patologíaRESUMEN
Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that typically has low-grade malignant potential. Although recurrences do occur, only approximately 25 cases of metastasizing AFX have been reported. Herein a patient with an AFX that metastasized and eventuated in death is described. Although AFX remains a diagnosis of exclusion, through this pedagogic case, the clinical, immunohistochemical, and genetic features that can assist in diagnosis are discussed.
Asunto(s)
Neoplasias Pulmonares/diagnóstico , Sarcoma/diagnóstico , Neoplasias Cutáneas/diagnóstico , Antígenos CD/análisis , Antígenos de Diferenciación Mielomonocítica/análisis , Biopsia , Cara , Resultado Fatal , Humanos , Neoplasias Pulmonares/secundario , Neoplasias Pulmonares/cirugía , Masculino , Persona de Mediana Edad , Mitosis , Cirugía de Mohs , Neprilisina/análisis , Sarcoma/secundario , Sarcoma/cirugía , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/cirugía , Vimentina/análisisRESUMEN
The term "signet ring" is used to describe a cell with an eccentric nucleus that is compressed to the periphery of the cell by a large cytoplasmic vacuole or by a substance accumulated within the cytoplasm. In pathology, these cells have been traditionally associated with adenocarcinomas. We describe two cases of cutaneous tumors that contained signet ring-like cells. Because of the morphology of the cells and the fact that one patient had a past history of lung cancer, the possibility of metastatic adenocarcinoma was considered. Upon further investigation, the tumors proved to be a primary cutaneous squamous cell carcinoma and a basal cell carcinoma; surgical management was curative. Because signet ring changes may pose a diagnostic challenge, we review the various benign and malignant cutaneous lesions that have been reported to contain signet ring cells and we explore the possible causative mechanisms of this phenomenon.
Asunto(s)
Carcinoma Basocelular/patología , Carcinoma de Células en Anillo de Sello/patología , Carcinoma de Células Escamosas/patología , Neoplasias Cutáneas/patología , Anciano , Anciano de 80 o más Años , Carcinoma Basocelular/cirugía , Carcinoma de Células Escamosas/cirugía , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Neoplasias Cutáneas/cirugíaAsunto(s)
Encefalitis por Varicela Zóster/diagnóstico , Foliculitis/diagnóstico , Herpes Zóster/diagnóstico , Herpesvirus Humano 3 , Infecciones Oportunistas/diagnóstico , Enfermedades Cutáneas Papuloescamosas/diagnóstico , Biopsia , Foliculitis/patología , Folículo Piloso/patología , Humanos , Queratinocitos/patología , Linfoma de Células B/complicaciones , Masculino , Persona de Mediana EdadAsunto(s)
Granuloma Anular/patología , Granuloma/patología , Escleromixedema/diagnóstico , Humanos , MasculinoRESUMEN
We describe two full-term infants who presented with congenital cutaneous candidiasis (CCC) and compare their clinical presentation and outcome with that of neonatal candidiasis and chronic mucocutaneous candidiasis. Although candidal vulvovaginitis occurs in up to one-third of pregnancies, CCC is uncommon and can be confused with more-serious pustular disorders that present in neonates. Greater awareness of CCC is essential to make an early diagnosis and distinguish it from other infections.
Asunto(s)
Candidiasis Cutánea/congénito , Candidiasis Cutánea/diagnóstico , Enfermedades del Recién Nacido/diagnóstico , Enfermedades del Recién Nacido/microbiología , Diagnóstico Diferencial , Femenino , Edad Gestacional , Dermatosis de la Mano/diagnóstico , Dermatosis de la Mano/microbiología , Humanos , Lactante , Recién Nacido , Masculino , Onicomicosis/diagnóstico , Onicomicosis/microbiologíaAsunto(s)
Enfermedades del Colágeno/patología , Dermatosis de la Mano/patología , Anciano , Femenino , HumanosAsunto(s)
Alopecia/etiología , Ácido Aminolevulínico/efectos adversos , Enfermedad de Bowen/tratamiento farmacológico , Fármacos Fotosensibilizantes/efectos adversos , Neoplasias Cutáneas/tratamiento farmacológico , Anciano , Enfermedad de Bowen/cirugía , Femenino , Humanos , Cirugía de Mohs , Fotoquimioterapia , Cuero Cabelludo , Neoplasias Cutáneas/cirugía , Insuficiencia del Tratamiento , Resultado del TratamientoRESUMEN
Although yaws is rare in developed countries, as worldwide travel has become commonplace, it is essential to recognize this condition when evaluating patients who traveled from endemic regions. Herein, we discuss a case of secondary yaws presenting as extensive expanding annular lesions to raise awareness of this condition.