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BACKGROUND: Chronic kidney disease (CKD) predispose to viral coinfections in patients submitted to renal replacement therapy (RRT); nevertheless, few reports have been performed to elucidate the current epidemiology within this population in Mexico. AIM: To estimate the prevalence of HBV, HCV, and HIV coinfection and to explore factors associated with prevalent coinfection in patients living with renal failure undergoing to RRT. METHODS: A multicenter cross-sectional recruitment across 21 units at the Mexican Institute of Social Security (IMSS) at the State of Mexico was performed during 2019. A standardized clinical questionnaire was performed to elucidate individual and relatives-related conditions. A treatment facility questionnaire was applied to the chief responsible of each unit to explore treatment facility variables. Serological testing, clinical, biochemical, and anthropometrical parameters were extracted from clinical records. RESULT: In 1,304 patients (57.5% male, mean age 45.5 (SD: 15.6) years, and 95.8% in hemodialysis), the prevalence of any viral coinfection was 3.14% (95% CI: 2.32%-4.23%). The highest viral coinfection prevalence were for HCV, HBV, and HIV, in which men and subjects diagnosed after 2010's had the highest rates. We identify that being submitted to peritoneal dialysis, being treated in a surrogated dialysis center and living with a close relative with prior hepatitis coinfection were associated factors for any viral coinfection. CONCLUSION: In patients submitted to RRT, the prevalence of viral coinfection remains high compared with general population. Screening strategies, medical awareness and targeted public healthcare policies should prioritize better care practices within patients submitted to RRT in Mexico.
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Coinfección , Infecciones por VIH , Hepatitis B , Hepatitis C , Humanos , Masculino , Persona de Mediana Edad , Femenino , Coinfección/epidemiología , Estudios Transversales , México/epidemiología , Diálisis Renal , Hepatitis C/complicaciones , Hepatitis C/epidemiología , Hepacivirus , Hepatitis B/complicaciones , Hepatitis B/epidemiología , Infecciones por VIH/complicaciones , Infecciones por VIH/epidemiología , Terapia de Reemplazo Renal , VIHRESUMEN
INTRODUCCIÓN: La Coordinación de Investigación en Salud del Instituto Mexicano del Seguro Social promueve acciones para la realización del Foro Sur de Investigación en Salud del Instituto Mexicano del Seguro Social (FSIS-IMSS), entre las que destacan la presentación de reportes de investigación. OBJETIVO: Analizar la actividad científica del FSIS-IMSS de 1995 a 2018 a través de los reportes de investigación publicados en el marco del Foro Sur. MATERIAL Y MÉTODOS: Estudio bibliométrico de los reportes de investigación publicados. Se elaboró una base de datos en el gestor EndNote X8 y se exportó a Excel para su análisis. Se empleó el Manual Metodológico de Indicadores Médicos 2017 para estandarizar la temática de investigación. Variables: productividad, colaboración, concentración y dispersión. Análisis: frecuencia y media, pruebas de Olmstead Tukey modificada por García de León, Shapiro-Wilk, r de Spearman y ji al cuadrado. RESULTADOS: 15,249 investigadores (el 53% mujeres) publicaron 6166 reportes de investigación. Ley de Price con ecuación: y = 130.13 e0.048x. Ley de Lotka conforma 45 grandes investigadores, 2899 medianos y 12,305 pequeños (p < 0.05). Colaboración alta: índice Subramanyan 0.8860 y tres autores como extensión (p < 0.05). Concentración temática moderada: índice Price 0.4922. Categoría temática dominante: diabetes mellitus. El modelo de Bradford explica la contribución de investigadores adscritos a 58 tipos de unidades, 10/58 aportaron 2054 reportes frente a 2061 de 57/58. CONCLUSIONES: La actividad científica del FSIS-IMSS en 1995-2018 tuvo mayor participación de mujeres y colaboración múltiple. Se observa una extensión de reportes constante de crecimiento exponencial y concentración de autores de reporte único. Discreta dispersión temática. Alta productividad de las unidades médicas de alta especialidad, los hospitales generales de zona y las instituciones educativas. BACKGROUND: The Health Research Coordination of the Mexican Institute of the Mexican Institute of Social Security promotes actions for the realization of the Southern Forum of Health Research of the Mexican Institute of Social Security (FSIS-IMSS), among which the presentation of research reports stands out. OBJECTIVE: Analyze the scientific activity of FSIS-IMSS from 1995 to 2018, through the research reports published in the framework of the Southern Forum. MATERIAL AND METHODS: Bibliometric study of published research reports. The database was created in the EndNote X8 manager and exported to Excel for analysis. Methodological Manual of Medical Indicators 2017 used to standardize research topics. Variables: productivity; collaboration; concentration; dispersion. Analysis: frequency, mean. Olmstead Tukey tests modified by García de León, Shapiro Wilk, r Spearman, Chi square. RESULTS: 15,249 researchers (53% women) published 6166 scientific reports. Law of Price with equation: y = 130.13 e0.048x. Lotka's law consists of 45 large researchers, 2899 medium and 12,305 small (p < 0.05). High collaboration: Subramanyan index 0.8860 and three authors as extension (p < 0.05). Moderate thematic concentration: Price index 0.4922. Olmstead Tukey test modified by García de León exposes dominant thematic category: diabetes mellitus. Model of Bradford explains: 10/58 different types of units according to secondment of researchers contributed 2054 reports; 57/58 contributed 2061. CONCLUSIONS: Scientific activity of the FSIS-IMSS, from 1995-2018 shows greater participation of women, multiple collaboration and extension of constant reports of exponential growth and concentration of single report authors. Discrete thematic dispersion. High productivity of high specialty medical units, general zone hospitals and educational institutions.
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INTRODUCTION: In 2000, malignant tumors were responsible for 12% of nearly 56 million deaths that occurred in the world from all causes. OBJECTIVE: To determine the incidence of cancer in a Cancer Care Unit of IMSS in Toluca, Mexico. MATERIAL AND METHODS: Prospective cross-sectional study; we identified the primary tumor, age, family history of cancer, comorbidities, risk factors, and ECOG in patients with newly diagnosed cancer. RESULTS: We identified 446 cases, 66.1% were women. The age group of age 50 to 59 had the highest number of cases (98). The most common cancers in women are breast, cervical, and ovarian cancer, and in men, testicular, prostate, and colorectal cancer. CONCLUSIONS: The most common cancers in both sexes were breast cancer, cervical cancer, colorectal cancer, ovarian cancer, and testicular cancer.
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Neoplasias/epidemiología , Academias e Institutos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Estudios Transversales , Femenino , Humanos , Incidencia , Masculino , México/epidemiología , Persona de Mediana Edad , Estudios Prospectivos , Factores de Riesgo , Seguridad Social , Adulto JovenRESUMEN
BACKGROUND: breast cancer (BC) is the leading cause of death secondary to malignancy in women. It ranks third in mortality in women in reproductive age, produced by non-modifiable (genetic and hormonal) and modifiable factors. Our objective was to describe and analyze the epidemiological characteristics of deaths from BC in the State of Mexico. RESULTS: of 273 verbal autopsies, the most common age (23.07 %) was between 40 and 49 years. The educational level of schooling were complete elementary school (20.51 %), incomplete elementary school (19.04 %) and complete high school (13.91 %). the institution with the highest number of patients was the Instituto Mexicano del Seguro Social with 139 (50.91 %). The towns with a higher frequency were Malinalco, Ayapango, Atizapán, Zacualpan and Apaxco. The Mortality was higher in Valle de Bravo, Coatepec Harinas and Toluca. CONCLUSIONS: the increase in BC has permitted the emergence of a new hypothesis known as endocrine disruption, according to this premise, this results from exposure to chemicals introduced into the environment by human activity capable of altering the hormonal balance.
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Neoplasias de la Mama/mortalidad , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias de la Mama/epidemiología , Estudios Transversales , Femenino , Humanos , México/epidemiología , Persona de Mediana Edad , Adulto JovenRESUMEN
BACKGROUND: One in eight women has risk to developing breast cancer in long life (12.2%) one out of each 28 is in risk of death by this disease. The most recognized risk factors are hormonals, genetics and environmentals. OBJECTIVE: To identify the frequency of risk factors for breast cancer patients. PATIENTS AND METHODS: A cross-sectional study was conducted in the Ambulatory Care Medical Unit 231, IMSS, in the medical records of 272 breast cancer patients in order to identify the major risk factors. RESULTS: 272 patients were studied, out of which 63 (23.1%) had no risk factor; 174 (64%) had 1 to 2 factors, 35 (12.9%) had 3 to 4 factors. The most common age group was 50-59 years. 80 women were menopausal, 28 (35%) had > 54 years, obesity was present in 35% of postmenopausal patients; with 29.8% of smokers, 16.9% had pregnancies long term > 30 years old. 14.3% were diabetics prior to breast cancer, and 12.2% had used exogenous hormones for > 5 years, 10.7% had experienced menarche < 11 years. Family background in first degree was 6.6% and for another cancer 32.4%. The detection by self examination was 91.5% and 1.1% by mastography. CONCLUSIONS: The most frequent risk factors included: overweight, obesity, smoking, exogenous hormones and pregnancy long term > 30 years. The method most frequently used for detection was self examination.